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The purpose with this project was to create future self-service points for Skånetrafiken. The ticket machines that are in use today are difficult to interact with and excluding to people who are sight impaired or uses a wheelchair. Since Skånetrafiken are going to implement new self-service solutions in 2019 they want suggestions on how it could be designed. We thought that this project was an exc
TV-on-Demand service has become one of the most popular Internet applications that continuously attracts higher user interests. With rapidly increasing user demand, the existing network conditions may not be able to ensure low start-up delay of video playback. Prefetching has been broadly investigated to cope with the start-up latency problem which is also known as user perceived latency. In this
Distributed e-Infrastructure is a key component of modern BIG Science. Service discovery in e-Science environments, such as Worldwide LHC Computing Grid (WLCG), is a crucial functionality that relies on service registry. In this paper we re-formulate the requirements for the service endpoint registry based on our more than 10 years experience with many systems designed or used within the WLCG e-In
Background: The risk of sustaining a graft rupture after anterior cruciate ligament reconstruction (ACLR) is high. Contributing risk factors are, however, still not clearly identified. Objective: The aim of this systematic review was to identify and quantify risk factors for graft rupture after ACLR. Methods: A systematic review with meta-analysis (PROSPERO CRD42020140129) based on PRISMA guidelin
Sponge phase nanoparticles are lipid-based particles with a porous structure, forming pores with sizes up to 13 nm in diameter. These particles have been proposed for drug delivery by loading cargo within the pores, similar to how ionisable nanoparticles are used today. The larger pores could allow for larger cargo to be delivered to cells. Sponge phase nanoparticles, 277 ± 29 nm in diameter, were
Due to rapid development of bacterial resistance against antibiotics, an emerging health crisis is underway, where ‘simple’ infections may no longer be treatable. Antimicrobial peptides (AMPs) constitute a class of substances attracting interest in this context. So far, research on AMPs has primarily focused on the identification of potent and selective peptides, as well as on the action mode of s
In this study, the use of cubosomes for topical delivery of the antimicrobial peptide (AMP) LL-37 was investigated. Topical delivery of AMPs is of great interest for treatment of skin infections caused by bacteria, such as Staphylococcus aureus. AMP containing cubosomes were produced by three different preparation protocols and compared: (i) pre-loading, where LL-37 was incorporated into a liquid
The controlled delivery of micronutrients to soil and plants is essential to increase agricultural yields. However, this is today achieved using fossil fuel-derived plastic carriers, posing environmental risks and contributing to global carbon emissions. In this work, a novel and efficient way to prepare biodegradable zinc-impregnated cellulose acetate beads for use as controlled release fertilize
Nanoparticle-based targeted drug delivery holds promise for treatment of cancers. However, most approaches fail to be translated into clinical success due to ineffective tumor targeting in vivo. Here, the delivery potential of mesoporous silica nanoparticles (MSN) functionalized with targeting ligands for epidermal growth factor receptor and C─C chemokine receptor type 2 is explored in lung tumors
Supramolecular hydrogels have attracted increasing attention in drug delivery, tissue engineering, and injectable biomaterials because of their high water content, good biocompatibility, and dynamic network structures. Cyclodextrin-based supramolecular systems can form network structures through host–guest interactions. These systems usually require mild cross-linking conditions and allow flexible
Protein therapeutics need to be formulated into an amorphous solid state to be stabilized, and this is efficiently done by spray drying together with a sugar matrix excipient. The characteristics of the produced powder are strongly dependent on process parameters, and therefore, spray drying offers the possibility of advanced particle engineering. In this thesis, trypsin was spray dried as a model
Protokoll fört vid årsstämma i LU Holding AB, org.nr 556500-1467, den 24 juni 2024 i Lund Närvarande aktieägare Antal aktier Antal röster Lunds universitet genom Erik Renström 100 __________ 100 __________ Summa 100 100 Dessutom var Kristina Eneroth och Christine Widstrand närvarande. § 1 Ordförande Stämman öppnades av Erik Renström som valdes till ordförande vid stämman. Noterades att ordföranden
Objective—To determine medium-term outcome after arterial switch operation for complete transposition in a population-based cohort.Design—Retrospective study of all 86 patients operated on at our institution from 1982 to 2000. Age at operation was 0-256 days (median 6 days); 28 (32%) had closure of a ventricular septal defect, 2 of whom had double outlet right ventricle. Additional surgery include
In this paper, we focus on uplink scheduling with the practical constraints imposed by the Long-Term Evolution/Long-Term Evolution-Advanced (LTE/LTE-A) standard. We consider multimedia traffic generated by mobile users with heterogeneous quality-of-service (QoS) requirements. To tackle the resulting time and frequency problem, we then propose an adaptive and potential aware scheduling scheme (APAS
This research aims to investigate nonionic hyperbranched polyesters (HBPs) derived from indole and lignin resources as new nontoxic antimicrobial coatings. Three nonionic HBPs with zero to two methoxy ether substituents on each benzene ring in the polymer backbones were synthesized by melt-polycondensation of three corresponding AB2 monomers. The molecular structures and thermal properties of the
