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The age-dependent association of risk factors with pancreatic cancer

BACKGROUND: Pancreatic cancer presents as advanced disease in >80% of patients; yet, appropriate ages to consider prevention and early detection strategies are poorly defined. We investigated age-specific associations and attributable risks of pancreatic cancer for established modifiable and non-modifiable risk factors.PATIENTS AND METHODS: We included 167 483 participants from two prospective US

Perioperative systemic chemotherapy in peritoneal carcinomatosis of lymph node positive colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is the preferred treatment of peritoneal carcinomatosis (PC) of colorectal carcinoma. Patients with positive lymph node status have worse survival after CRS-HIPEC, which is probably due to higher rates of systemic failure. In this study, we analysed the effect of administration and timing of systemic chemot

Randomized study on adjuvant chemotherapy in stage I high-risk ovarian cancer with evaluation of DNA-ploidy as prognostic instrument

PURPOSE: Adjuvant chemotherapy versus observation and chemotherapy at progression was evaluated in 162 patients in a prospective randomized multicenter study. We also evaluated DNA-measurements as an additional prognostic factor.PATIENTS AND METHODS: Patients received adjuvant carboplatin AUC 7 every 28 days for six courses (n = 81) or no adjuvant treatment (n = 81). Eligibility included surgicall

Nuclear Nonproliferation Objectives of Permanence with Accountability at Stake : The Role of International Law in the Interlude Between the Tenth and the Eleventh Review Conference of the Parties to the Treaty on the Non-proliferation of Nuclear Weapons

This chapter aims to discuss the meaning and implication, in terms of international law, of the concept of permanence with accountability in the framework of the tenth Review Conference of the States party to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) and in the interval between this and the next Review Conference. After contextualizing the concept of permanence with accountabili

ErbB2 status and the benefit from two or five years of adjuvant tamoxifen in postmenopausal early stage breast cancer

AIM: We aimed to study the importance of erbB2 status in early stage postmenopausal breast cancer for patients who participated in a trial of five vs. two years of adjuvant tamoxifen.PATIENTS AND METHODS: We analysed the erbB2 status of the tumours from 577 patients participating in the trial, either by a DNA amplification assay (n = 181) or by measurement of the protein level with flow cytometry

Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair

PURPOSE: Acquired chemoresistance is a frequent event in small cell lung cancer (SCLC), one of the deadliest human malignancies. Histone deacetylase inhibitors (HDACi) have been shown to synergize with different chemotherapeutic agents including cisplatin. Accordingly, we aimed to investigate the dual targeting of HDAC inhibition and chemotherapy in SCLC.EXPERIMENTAL DESIGN: The efficacy of HDACi

A Biological Signature for Breast Ductal Carcinoma In Situ to Predict Radiotherapy Benefit and Assess Recurrence Risk

PURPOSE: Ductal carcinoma in situ (DCIS) patients and their physicians currently face challenging treatment decisions with limited information about the individual's subsequent breast cancer risk or treatment benefit. The DCISionRT biological signature developed in this study provides recurrence risk and predicts radiotherapy (RT) benefit for DCIS patients following breast-conserving surgery (BCS)

Importance of individual residues in hydrophobic patch PLVIVGL (1481-1487) in FV-Short for synergistic TFPIα cofactor activity with protein S, an alanine-scanning study: AlphaFold-mediated prediction of FV-Short/TFPIα/protein S trimolecular complex structure

BackgroundIn the splice variant factor (F)V-Short, 702 residues are deleted from the B domain, resulting in exposure of an acid region (AR2; 1493-1537) that binds TFPIα. FV-Short and protein S serve as synergistic TFPIα cofactors in inhibition of FXa. In the preAR2 region, a hydrophobic patch PLVIVGL (1481-1487) is crucial for synergistic TFPIα-cofactor activity and assembly of FV-Short, TFPIα, an

Pursuing drawdown- carbon sequestration potential of arable land in Södertälje by alternative management practices

Connected to the ongoing global challenges relating to soil fertility loss and food security, there has been a recent upswing of alternative management practices (AMPs) within the agricultural sector. These methods are often focused on maximising soil health by safeguarding the below ground ecosystem and by increasing soil organic content. Consequently, AMPs tend to build resilience towards distur

Vårdslös rådgivning – Vad innebär vårdslös rådgivning vid finansiell rådgivning samt investeringsrådgivning?

Till följd av finanskrisen förlorade konsumenter genom placeringar i riskfyllda finansiella instrument stora delar av sina investeringar. Under åren 2008 och 2009 inkom fler klagomål till Finansinspektionen och Konsumentverket jämfört med tidigare år om att många konsumenter via rådgivning rekommenderats produkter som inte motsvarat den risk de varit beredda att ta eller att information om risken The aftermath of the financial crisis meant that many consumers lost parts of their investments because they had invested their savings in risky financial instruments. Between the years of 2008 and 2009, the Swedish Financial Supervisory Authority, Finansinspektionen, and the Swedish Consumer Agency, Konsumentverket, received more complaints, compared to previous years, regarding financial advisor

Design of an active orthosis for improved rehabilitation of stroke patients

Är exoskelett framtiden för stroke rehabilitering? Strokepatienter får ofta minskad rörlighet vilken i viss mån går att återfå genom rehabilitering. Exoskelett öppnar dörrar för nya möjligheter inom detta . Tänkt dig att du sitter i soffan med ditt morgonkaffe och gör dig redo för att återigen göra dina arm-övningar. Varför var det just du som skulle få den där stroken i somras? Hela ditt liv väTo regain mobility in an affected limb after a stroke it is important to be consistent with rehabilitation exercises. The purpose of this project was to create an active orthosis for the elbow joint. The intended use of the orthosis is to help stroke patients during rehabilitation and to enable the possibility to use the orthosis at home without the assistance of a physiotherapist or other help. T

nytt dok

nytt dok 1 Instuderingsfrågor till Lena Halldenius’ Liberalism Obs. svaren lämnas inte in. 1. Vad är en ideologi? 2. Vad utmärker nyliberalismen eller libertarianismen? 3. Vilken är liberalismens människosyn? 4. I vilket förhållande står liberalismen till värderelativismen? 5. Vad är en genuin preferens, enligt Halldenius? 6. Vilken syn på frihet måste varje liberal acceptera? 7. Vad kallas den to

https://www.fil.lu.se/media/utbildning/dokument/kurser/FPRA11/20141/Instuderingsfrgor_Halldenius.pdf - 2026-05-17

Löneprinciper

Löneprinciper | Akademikerföreningen vid Siemens Energy AB Hoppa till huvudinnehåll Öppna sökruta Öppna Huvudmeny Sök på saco.se Om oss Stadgar Kollektivavtal Bli medlem Nyheter Presentation "Will I be poor when I retire" Nyhetsbrev Löneskola 2026 Lecture "Swedish pension system", 15th of April 11:45 Lecture "Working in Sweden" 16th of December Presentationsmaterialet från pensionsföreläsningen 15

https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/privat/akademikerforeningen-vid-siemens-i-finspang/vart-uppdrag/lon/lonesamtal/loneprinciper/ - 2026-05-17

Sustainability-plan-for-lund-university-2020-2026-rev-2025

Sustainability Plan for Lund University 2020-2026 Sustainability Plan for Lund University 2020-2026 REVISED 2025 | APPROVED BY THE VICE-CHANCELLOR 19 JUNE 2025 REG. NO STYR 2025/1078 | LUND UNIVERSITY P H O T O C O V E R : JO H A N P E R S S O N | P H O T O : H Å K A N R Ö JD E R , K E N N E T R U O N A , JO H A N P E R S S O N Contents 1. INTRODUCTION 4 ...........................................

https://www.staff.lu.se/sites/staff.lu.se/files/2026-01/sustainability-plan-for-lund-university-2020-2026-rev-2025.pdf - 2026-05-17

CMI 33

CMI 33 1 COURSE MANAGEMENT INFO Version 3.1 – September 2020 2 1. INTRODUCTION If you are reading this, you are probably going to teach or even coordinate one of our courses – or you have some interesting plans for a course that you would want to pitch. In any case: Welcome to Graduate School! Glad to have you onboard! Any lingering questions after having read this document? Just ask! If you are s

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2020-09/CMI%2033.pdf - 2026-05-17

Maria Messing

Professor Contact details Email: maria [dot] messing [at] fysik [dot] lu [dot] se Phone: +46 46 222 36 91 Mobile: +46 70 640 61 94Organisation Solid State Physics Visiting address: Professorsgatan 1, Lund Room number: B102 Service point: 14 WebpageMaria Messings profile in Lund University research portalOther affiliations Coordinator LTH Profile Area: Nanoscience and Semiconductor Technology Membe

https://www.sljus.lu.se/maria-messing - 2026-05-17