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Many neurons typically fire action potentials in brief, high-frequency bursts with specific consequences for their synaptic output. Here we have examined short-term plasticity engaged during burst activation using electrophysiological recordings in acute rat hippocampal slices. We show that CA3-CA1 glutamate synapses exhibit a prominent depression of presynaptic release probability for approximate
In rodent models of Parkinson disease in which transplants of dissociated rodent and human embryonic mesencephalic tissue, rich in dopamine neurons, have been studied, only 5-20% of the dopamine neurons survive the implantation procedure. We have investigated the effects of inhibiting free radical generation with two lazaroids, U-74389G and U-83836E, on the survival of embryonic rat dopamine neuro
Context. To use the data in the future Gaia catalogue it is important to have accurate estimates of the statistical uncertainties and correlations of the errors in the astrometric data given in the catalogue. Aims. In a previous paper we derived a mathematical model for computing the covariances of the astrometric data based on series expansions and a simplified attitude description. The aim of th
Aim: The purpose of this study was to investigate the relationship between maximum oxygen uptake (VO2PEAK) and body fat in young children on a population-based level. Methods: Participants were 586 children (311 boys and 275 girls) aged 6.8 +/- 0.4 years, recruited from a population-based cohort. VO2PEAK was measured by indirect calorimetry during a maximal exercise test. Percent body fat (BF%) wa
A cochlear implant (CI) is a device that provides individuals with severe to profound hearing impairment (SPHI) with auditory stimulation, which makes it possible for them to develop skills related to spoken communication. We have little knowledge about how hearing with a CI influences cognitive and communicative development and there is a need for development of methods for assessment. The genera
Background: Respiratory agents may be detected in the oropharynx of healthy individuals. The extent of this condition and the reasons behind it are largely unknown. The objective of this study was to determine the factors associated with the presence of respiratory agents in the oropharynx of adolescents healthy enough to attend school activities. Methods: On a single day in December, samples from
Environmental impacts from incineration, decentralised composting and centralised anaerobic digestion of solid organic household waste are compared using the EASEWASTE LCA-tool. The comparison is based on a full scale case study in southern Sweden and used input-data related to aspects such as source-separation behaviour, transport distances, etc. are site-specific. Results show that biological tr
Memory integration is how series of similar memories can merge into overlapping representations as one abstract model of behavior to anticipate present and future episodes – facilitating instrumental use of episodic experience for higher-order inferences. Previous research has showed that a novel memory of reward can travel backwards in time through episodic memory and generalize its contents to p
The continued increased exposure to chemicals and the increasing prevalence of allergic contact dermatitis makes it important to develop accurate testing methods and strategies to assess chemical sensitizers. The Genomic Allergen Rapid Detection (GARD) assay is an in vitro test method that uses the transcriptional response of a myeloid cell line, MUTZ-3, after exposure to test substances to assess
To utilize sugars as a feedstock for renewable industries, the feedstock often needs to be very pure. This is due to ionic species contaminating the sugar feedstock being potent catalyst poisons in many cases. To remove ionic species from the sugar feedstock, it is dissolved and purified using packed ion-exchange columns. In this report, a lab-scale setup of a large scale ion-exchange setup was co
Digitaliseringen har revolutionerat våra samhällen. Hur vi kommunicerar och interagerar med varandra och hur vi handlar produkter och tjänster har över de senaste åren varit föremål för drastiska förändringar. Bakom dessa förändringar står ett fåtal digitala jättar. Trots att förändringarna har ökat konsumentvälfärden och i regel varit positiva, har farhågor lyfts. Detta har inte minst uppmärksammDigitalization has revolutionized our societies. How we communicate and interact with one another and how we purchase goods and services has changed drastically. A select few technological giants are the driving force behind these changes. Despite the increase in consumer welfare and the overall heightened standard of living, concerns have been raised, especially within the discourse of competitio
Thesis purpose: This research investigates the effect of six specific consumers’ characteristics, i.e. fashion leadership, shopping enjoyment, instrumental and terminal materialism, green selfidentity, and social influence susceptibility, on consumers’ attitude towards a product-service system (a use-PSS) in the form of second-hand clothing rental. The relationship between attitude and consumers’
The main purpose of this thesis report is to examine the theory of ecosystems within the mobile industry and to create a framework that makes it possible to comprehend and manage the value creation in a practical setting. The theoretical part is characterized by mobile ecosystems since they are considered as a fast pace sector where new innovations are ruling the market. Due to these circumstance
In recent years, as Internet of Things (IoT) and machine learning technologies have advanced, there has been increasing interest in the study of energy-efficient and flexible architectures for embedded systems. To bridge the performance gap between microprocessors and memory systems, Near-Data Processing (NDP) was introduced. Although some works have implemented NDP, few of them utilize the microp
Population-based studies on contact allergy to p-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were interviewed, and a random sample (n = 2,739) was patch tested to PPD. Overall, 5,286 individuals (50.9%) reported having us
Male patients with terminal renal failure are often infertile and exhibit an abnormal sex hormone pattern in plasma. We studied patients in all chronic kidney disease (CKD) stages to determine plasma levels of anti-Müllerian hormone (AMH), a Sertoli cell-derived marker, and other sex hormones. Seventy-eight male patients with CKD stages 1-5 and a median age of 40 years (22-50 years), as well as 20
