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Sensory traits shape animal lifestyles due to the central role they play in retrieving and processing environmental information. However, being some of the most energetically expensive tissues to build and maintain, ecological demands often modulate investment in these organs. Evidence that ecology shapes the evolution of sensory traits is plenty, but is heavily biased towards vertebrates and has
Purpose. Continuous minor steps of improvement in the management of breast cancer have resulted in decreased mortality rates during the last decades. The aim of this study was to compare the clinical outcome of patients with stage I breast cancer diagnosed during two time periods that differed with respect to adjuvant systemic therapy. Material and methods. The studied population consisted of all
ESI-LC-MS/MS method with isotope dilution and SPE based on cation-exchange was developed for determination of free and total Nε-(1-Carboxymethyl)-l-Lysine (CML) and free Nε-(1-Carboxyethyl)-l-Lysine (CEL). The use of nonafluoropentanoic acid in mobile phase was omitted, SPE recoveries of 82±3% and 91±10% (n=6) for CML and CEL respectively and, calibration curves (R(2)>0.9985) were attained. The me
Background and purpose: Patients with focal cartilage lesions experience functional impairment. Results for biological treatments in the middle-aged patient is poor. Previous studies with focal prosthetic inlay resurfacing have shown a higher risk of conversion to total knee replacement at mid-term follow-up. A novel customized implant (Episealer, Episurf, Stockholm, Sweden) has been proposed to i
A search for pair production of bottom squarks in events with hadronically decaying τ-leptons, b-tagged jets, and large missing transverse momentum is presented. The analyzed dataset is based on proton-proton collisions at √s=13 TeV delivered by the Large Hadron Collider and recorded by the ATLAS detector from 2015 to 2018, and corresponds to an integrated luminosity of 139 fb−1. The observed da
Objective: This review aims to consolidate contemporary literature examining the impact of physical activity (PA) and exercise on sensitisation and pain perception in individuals with chronic non-specific low back pain (cLBP). Methods: A semi-systematic approach was employed, utilising Pubmed and PEDro databases for the period between 2013-2023. Eligibility criteria included randomised control tri
Policymakers are increasingly demanding that their investments in research and knowledge production should yield returns. The interest of evaluating the societal impact of research has grown rapidly as research funders request evidence that their investments lead to public benefits. This thesis is a study of how the Research Council of Norway has operationalized such demands into new evaluation pr
Purpose of this research The ability to quickly respond presupposes logistics systems designed to be responsive; supply chains must prepare to act if specific circumstances occur. By investigating ‘preparedness’ in a defence logistics context, the overall research objectives are to define ‘preparedness’ and to advance defence logistics as an academic research area. Design/methodology/approach We
Background: Some patients with atrial fibrillation (AF) cannot be treated with vitamin K antagonists (VKAs) and will therefore not receive effective thromboprophylaxis. The primary objective of the present Phase II trial (NCT00623779) was to assess the feasibility of conducting a study with a novel oral anticoagulant, the direct thrombin inhibitor AZD0837, in patients with AF unable or unwilling t
A search is presented for production of a heavy up-type quark (t') together with its antiparticle, assuming subsequent decay to a W boson and a b quark, t'(t) over bar' -> W(+)bW(-)(b) over bar. The search is based on 1.04 fb(-1) of proton-proton collisions at root s = 7 TeV collected by the ATLAS detector at the CERN Large Hadron Collider. Data are analyzed in the lepton + jets final state, chara
Background: von Willebrand disease (VWD) type 1 is a congenital bleeding disorder caused by genetic defects in the von Willebrand factor (VWF) gene and characterized by a reduction of structurally normal VWF. The diagnosis of type 1 VWD is difficult because of clinical and laboratory variability. Furthermore, inconsistency of linkage between type 1 VWD and the VWF locus has been reported. Objectiv
To improve, it’s crucial to see! Vital characteristics of Lean are visualisation and transparency, i.e. allowing everyone to see all what occurs in production. A common tool for this purpose is Value Stream Mapping (VSM). Due to varying flows, performing a successful VSM in construction confers additional challenges. In this paper, lessons learned from successful VSM studies in construction are pr
Objective: The aim of the study was to determine survival outcome in patients with serous cancer in the ovary, fallopian tube, peritoneum and of undesignated origin. Methods: Nation-wide population-based study of women. ≥. 18. years with histologically verified non-uterine serous cancer, included in the Swedish Quality Registry for primary cancer of the ovary, fallopian tube and peritoneum diagnos
Background: People in treatment for substance use disorder commonly have comorbid personality disorders, including antisocial personality disorder. Little is known about treatments that specifically address comorbid antisocial personality disorder. Methods: Self-rated help received for antisocial personality disorder was assessed during follow-ups at 3, 9 and 15 months post-randomization of a rand
Background Transcatheter aortic valve replacement (TAVR) has become an established therapeutic option for patients with symptomatic, severe aortic valve stenosis (AS) who are ineligible or at high risk for conventional valvular surgery. In Northwestern Europe, the TAVR technology is also increasingly used to treat patients with an intermediate risk profile. Methods and results The study was design
Background: Practices regarding hospitalisation of children at diagnosis of type 1 diabetes vary both within countries and internationally, and high-quality evidence of best practice is scarce. The objective of this study was to close some of the gaps in evidence by comparing two alternative regimens for children diagnosed with type 1 diabetes: hospital-based care and hospital-based home care (HBH
The present contribution focuses on the mathematical techniques used to solve steady state metabolic models for the case of an overdetermined system. Even when parts of the system are underdetermined it is possible to solve the model partially and obtain statistically meaningful results. This is illustrated with data gathered from a set of E. coli W3110.shik1 phosphate- or carbon-limited continuou
Stress-related disorders are a frequent cause for sick leave, with consequences such as great distress and adverse economic effects for the affected person and substantial costs for society. Identifying effective interventions that facilitate return to work is thus important. The aim of this study was to evaluate the effectiveness of the 16-week Redesigning Daily Occupations program as a work reha
This thesis studies how subject extractions are accepted in Scandinavian (Danish, Norwegian, Swedish and Fenno-Swedish) through an extensive acceptability judgment study. The results from the study were compared with previous research and analyzed against accounts on why subject extraction constraints occur and why the acceptance of subject extractions in Scandinavian vasty varies. The subject ext
