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Hematopoietic stem cells (HSCs) are of great importance for the body and can be used to treat diseases such as leukemia or autoimmune conditions. To be able to use HSCs more extensively in therapies we need to know more about how they are being regulated, one way to do this is by knocking down genes with RNA interference. In this project we test a new micro RNA (miRNA), called miR30E, to investiga
Defects in the mitochondrial protein frataxin are responsible for Friedreich ataxia, a neurodegenerative and cardiac disease that affects 1:40,000 children. Here, we present the crystal structures of the iron-free and iron-loaded frataxin trimers, and a single-particle electron microscopy reconstruction of a 24 subunit oligomer. The structures reveal fundamental aspects of the frataxin mechanism.
Cells continuously export, import, and recycle molecules over the plasma membrane. Internalization, i.e. cellular import of extracellular material, is a fundamental process, which provides cells with nutrients and enables the immune cells of higher organisms to remove debris, sample their surroundings for antigens and to fight microbes. Moreover, internalization regulates complex cellular signalli
Achieving QoS-based broadband wireless access means a lot for the people living in the information age. WiMAX has evolved now into a stage that we can say it can meet this demand. From among the various fields to study in this domain, call admission and scheduling are the strongest tools in our hand to ensure QoS. On the other side, exploiting mesh topology is a good technique to increase the netw
The use of volatile anaesthetics has increased in situations where conventional anaesthetic machines are inadequate or unavailable, for example, cardiac surgery and intensive care. The disposable anaesthetic conserving device, AnaConDa (R), allows vaporization of liquid volatile anaesthetics from a syringe pump and rebreathing of exhaled anaesthetic. Clinical use requires understanding of device-s
Inhaled antibiotic treatment of cystic fibrosis-related bacterial biofilm infections is challenging because of the pathological environment of the lungs. Here, we present an "environment-adaptive" nanoparticle composed of a solid poly lactic-co-glycolic acid (PLGA) core and a mucus-inert, enzymatically cleavable shell of d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) for the site-specifi
Despite the initial promise of immunotherapy for CNS disease, multiple recent clinical trials have failed. This may be due in part to characteristically low penetration of antibodies to cerebrospinal fluid (CSF) and brain parenchyma, resulting in poor target engagement. We here utilized transcranial macroscopic imaging to noninvasively evaluate in vivo delivery pathways of CSF fluorescent tracers.
Background: Serially interconnected microfluidic devices enable advanced applications such as multi-step chemical processing and multi-organ-on-chip systems. However, managing these systems presents challenges due to interdependent fluid dynamics in their connecting channels, where even minor disturbances can propagate throughout the network, affecting overall system performance. Methods: This stu
MILJÖVETENSKAP Preliminärt schema 2022-10-05 Kurs: MVEN16 Klimatpolitik, samhällsstyrning och kommunikation, HT22 Kursansvarig: RH: Roger Hildingsson, Statsvetenskapliga inst; roger.hildingsson@svet.lu.se Lärare: CD: Carl Dalhammar, IIIEE; carl.dalhammar@iiiee.lu.se KH: Karl Holmberg, Statvetenskapliga inst; karl.holmberg@svet.lu.se JK: Jamil Khan, Miljö- och energisystemanalys, LTH; jamil.khan@mi
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2022-10/Schema%20MVEN16%20HT22_PREL_5okt22.pdf - 2026-06-22
Centrum för miljö- och klimatforskning, CEC, Miljövetenskaplig Utbildning, Sölvegatan 37, 223 62 Lund ht t p:/ / www.miljovet enskap.lu.se/ Preliminärt Schema MVES04 - Miljöövervakning, 15p VT21 Kurstid: 24 mars - 31 maj Kurschef: Adam Kristensson, tel:046-2227645, email: adam.kristensson@nuclear.lu.se Yann Clough, tel: 046-2226831, email: yann.clough@cec.lu.se Lärare: Namn Email AKR Adam Kristens
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-02/MVES04_Schema%202021_210219.pdf - 2026-06-22
Background: Traumas to the head and neck are common in sports and often affects otherwise healthy young individuals. Sports-related concussions (SRC), defined as a mild traumatic brain injury (mTBI), may inflict persistent neck and shoulder pain, and headache, but also more complex symptoms, such as imbalance, dizziness, and visual disturbances. These more complex symptoms are difficult to identif
In this work the intermetallic systems formed by transition-metals from group 5 to 9 with Ga, In and Zn have been experimentally and theoretically studied in detail. Syntheses, compositional analyses, X-ray and neutron diffraction (single crystal as well as powder) and measurements of physical properties, e.g. magnetic susceptibility and resistivity has been made for all compounds. Electronic-stru
Nytt Schema Centrum för miljö- och klimatforskning, CEC, Miljövetenskaplig Utbildning, Sölvegatan 37, 223 62 Lund http://www.miljovetenskap.lu.se/ Preliminärt Schema MVES04 - Miljöövervakning, 15p VT21 Kurstid: 24 mars - 31 maj maj Kurschef: Adam Kristensson, tel:046-2227645, email: adam.kristensson@nuclear.lu.se Yann Clough, tel: 046-2226831, email: yann.clough@cec.lu.se Lärare: Namn Email AKR Ad
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-02/MVES04_Schema%202021_210219.xlsx - 2026-06-22
https://www.geriatrik.lu.se/geriatrics/education - 2026-06-23
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 15 v 17 - 2021. UNIVERSITETSGEMENSAMT Se rektors vårhälsning till medarbetare och studenter* Rektor Erik Renström tackar alla medarbetare och studenter för de insatser som gjorts under pandemin och allt tålam
https://www.cec.lu.se/sites/cec.lu.se/files/2021-05/LU-gemensamt%20Mejlutskick%20Nr%2015-v17-2021.pdf - 2026-06-23
Background We aimed to document international practices in small-bowel capsule endoscopy (SBCE), measuring adherence to European Society of Gastrointestinal Endoscopy (ESGE) technical and clinical recommendations. Methods Participants reached through the ESGE contact list completed a 52-item web-based survey. Results 217 responded from 47 countries (176 and 41,
