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Insulinlike growth factor. 1 (IGF-1) has growth-promoting effects on myeloma cells in vitro as well as in vivo. In this study, we measured the concentration of IGF-1 and its major binding protein, IGF-binding protein 3 (IGFBP-3), in serum from 127 patients with multiple myeloma. Serum had been drawn at the time of diagnosis, before treatment With highdose melphalan. IGFBP-3 in myeloma patients (1.
High-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare decisions oBackgroundHigh-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare d
MILJÖVETENSKAP Preliminärt schema MVEN24 Kurs: Tillämpad Miljövetenskap Kursansvarig: Håkan Wallander Lärare: Deniz Koca , Radhlinah Aulin , Per Erik Isberg , Linda Lundmark Lokaler: Vitmossan Litteratur: Ingen Studieteknik: Läs om studieverkstaden Studenträttigheter: Läs om dina rättigheter och skyldigheter som student Likabehandling: Läs Lunds Universitets likabehandlingsplan för studenter Pedag
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven24_ht19x.pdf - 2026-07-10
Namnlös Reading list for Sustainable Services (SEMA54), 7,5 credits The reading list was approved by the Board of the Department of Service Studies 2023-05-24. The reading list is valid from 2023-11-29. Högskolan i Borås (latest). Guide till Harvardsystemet. Borås: Högskolan i Borås. [51 p.]. Https://www.hb.se/biblioteket/akademiskt-sprak/referera-till-kallor/guide-till-harvardsystemet/ Benn, Suza
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2023-05/LL_SEMA54_eng_HT23_230524.pdf - 2026-07-10
Lithium-ion battery safety is a topic of large importance, and testing is associated with large costs. Safety evaluation is therefore needed also at an early stage in cell design and development, in order to evaluate potential short-comings or to screen large platforms of materials and cells. Previous thermal runaway tests on lab-scale cells have, however, indicated differences in heat release and
This paper employs a biopolitical framework to critically analyse Swedish International Development Cooperation Agency’s (Sida) development and humanitarian policies, focusing on how these align with broader biopolitical strategies aimed to shape the lives of populations in recipient countries. Through a critical discourse analysis of four key policy documents, the study addresses the central ques
KEFUs stöd till forskning med koppling till den skånska myllan kan delas in i två delar – basforskning och strategiska forskningsprojekt. KEFUs basforskningKEFUs basforskning syftar till att utveckla kunskap och aktiviteter rörande ledning, organisation och demokrati i kommunal och regional verksamhet och på så sätt stödja de anställdas arbete med dessa frågor.Inom ramen för basforskningen ingår k
https://www.ehl.lu.se/organisation/forskningsnatverk/kefu/forskning-kefu - 2026-07-09
This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3
The CRISPR/Cas9 system is a versatile tool for functional genomics and forward genetic screens in mammalian cells. However, it has been challenging to deliver the CRISPR components to sensitive cell types, such as primary human hematopoietic stem and progenitor cells (HSPCs), partly due to lentiviral transduction of Cas9 being extremely inefficient in these cells. Here, to overcome these hurdles,
In the present study, two types of micro-pin–fin configurations were fabricated on silicon surfaces by a dry etching method, i.e., staggered pin fins (#1) and aligned pin fins with empty areas (#2). The micro-pin–fin surfaces were then further modified by depositing FeMn oxide nanoparticles (∼35 nm) electrostatically for 8 h and 16 h, respectively, namely #1-8h, #1-16h, #2-8h and #2-16h. Subcooled
The anticipated growth in the aging population will drastically increase medical needs of society; of which, one of the largest components will undoubtedly be from orthopedic-related pathologies. There are several proposed solutions being investigated to cost-effectively prepare for the future-pharmaceuticals, implant devices, cell and gene therapies, or some combination thereof. Gene therapy is o
Understanding how cancer cells regulate endocytosis during the cell cycle could lead us to capitalize this event pharmacologically. Although certain endocytosis pathways are attenuated during mitosis, the endocytosis shift and regulation during the cell cycle have not been well clarified. The conventional concept of glucose-regulated proteins (GRPs) as protein folding chaperones was updated by dis
Objective: To validate the prediction model for successful vaginal birth after cesarean delivery (VBAC) based on variables easily obtainable at the first antenatal visit, in a Spanish population. Methods: Retrospective observational study. Women with a single live fetus in cephalic presentation with one previous low-transverse CD who underwent trial of labor after cesarean delivery (TOLAC) at ≥37
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
