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Background: Previous in vitro studies have shown that mucin 4 (MUC4) confers resistance toward gemcitabine in pancreatic cancer cells. To date, there are few clinical studies corroborating these findings. The aim of this study was to evaluate the predictive impact of MUC4 expression on survival in patients with resectable pancreatic cancer receiving adjuvant gemcitabine. Materials and methods: MUC
Aim It is a constant challenge for people with type 1 diabetes to maintain appropriate levels of HbA1c, blood pressure and blood lipids in order to prevent or delay deleterious effects of their illness. This study sought to investigate if Sense of Coherence (SOC) is associated with clinical risk factors in people with type 1 diabetes. Methods Questionnaire data, including measure of SOC, was colle
How people wake up and regain alertness in the hours after sleep is related to how they are sleeping, eating, and exercising. Here, in a prospective longitudinal study of 833 twins and genetically unrelated adults, we demonstrate that how effectively an individual awakens in the hours following sleep is not associated with their genetics, but instead, four independent factors: sleep quantity/quali
BACKGROUND: Drug-resistant epilepsy (DRE) in selected individuals with the rare tuberous sclerosis complex (TSC) may benefit from resective epilepsy surgery. Furthermore, associated neuropsychiatric disorders (TAND) are common in patients with TSC; however, long-term data on how surgery affects neuropsychiatric comorbidities are sparse.MATERIALS AND METHODS: Two retrospective approaches were used
The cytoplasmic protein AXIN1 is involved in the Wnt signalling pathway and its expression is increased in patients with endometriosis compared with healthy controls. The aim of the present cross-sectional study was to further assess the levels of AXIN1 and other inflammatory biomarkers in patients with endometriosis. Patients with laparoscopy-verified endometriosis were recruited (n=172) and com
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 38 v 48 - 2020. CORONARELATERAT Undervisning och examination ska övergå ännu mer till digitalt Smittspridningen ökar i hela samhället och från den 24 november gäller i Sverige att allmänna sammankomster och o
https://www.cec.lu.se/sites/cec.lu.se/files/2021-01/LU-gemensamt%20Mejlutskick%20Nr%2038-2020-v48.pdf - 2026-07-13
Spinal cholinergic neurons are critical for motor function in both the autonomic and somatic nervous systems and are affected in spinal cord injury and in diseases such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy. Using two screening approaches and in situ hybridization, we identified 159 genes expressed in typical cholinergic patterns in the spinal cord. These include two g
A comparison between three different types of particle sizing instruments (fast mobility particle sizer, FMPS; electrical low pressure impactor, ELPI; and scanning mobility particle sizer, SMPS) and one condensation particle counter (CPC) was made to compare instrument response in terms of size distributions and number concentration. Spherical oil droplets in 39 different sizes, with geometric mea
I dagens samhälle kämpar företag för att höras och synas i det överflöd av information som finns tillgänglig. Ett särskiljande kännetecken har därmed blivit ett mycket viktigt kommunikationsmedel för företag. I detta kännetecken ligger ofta ett betydande värde i form av goodwill och image och attityd hos förbrukarna. Inte sällan är det hela koncept som förmedlas i ett komplicerat byggande av relat
BackgroundWe aimed to evaluate if optimization by maximizing QRS duration (QRSd) reduction is feasible in an all-comer cardiac resynchronization therapy (CRT) population, and if reduced, QRSd is associated with a better clinical outcome.MethodsPatients with LBBB receiving CRT implants during the period 2015–2020 were retrospectively evaluated. Implants from 2015–2017 were designated as controls. S
Background: Voluntary self-exclusion from gambling is a common harm reduction option for individuals with gambling problems. Multi-operator, nationwide self-exclusion services are rare, and a system introduced in the highly web-based gambling market of Sweden is a rare and recent example. However, where web-based casino gambling and web-based betting are the predominate gambling types in those see
MILJÖVETENSKAP Preliminärt schema 181009 Kurs: MVET01 Tillämpa Industriell Miljöekonomi Kursansvarig: Charlotte Leire Lärare: Torbjörn Brorson, Heather Schoonover, Åke Thidell, Lars Hansson, Beatrice Kogg, Anna Bruun Månsson, Philip Peck, Julia Nussholz, Katherine Whalen Lokaler: Mossen Öster i Ekologihuset (i några fall på IIIEE) Litteratur: Studieteknik: Läs om studieverkstaden Studenträttighete
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet01_2018_181009x.pdf - 2026-07-13
MILJÖVETENSKAP Preliminärt schema 181018 Kurs: MVET01 Tillämpa Industriell Miljöekonomi Kursansvarig: Charlotte Leire Lärare: Torbjörn Brorson, Heather Schoonover, Åke Thidell, Lars Hansson, Beatrice Kogg, Anna Bruun Månsson, Philip Peck, Julia Nussholz, Katherine Whalen Lokaler: Mossen Öster, Ekologihuset (i några fall IIIEE) Litteratur: Studieteknik: Läs om studieverkstaden Studenträttigheter: L
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet01_2018_181018.pdf - 2026-07-13
Objective. Costimulatory receptor CD226 plays an important role in T cell activation, differentiation, and cytotoxicity. This study was undertaken to investigate the genetic association of CD226 with susceptibility to systemic lupus erythematosus (SLE) and to assess the functional implications of this association. Methods. Twelve tag single-nucleotide polymorphisms (SNPs) in CD226 were typed in 1,
