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Doxorubicin (DOX) is a cornerstone drug in the treatment of osteosarcoma. However, achieving sufficient concentration in the tumor tissue after systemic administration with few side effects has been a challenge. Even with the most advanced nanotechnology approaches, less than 5% of the total administered drug gets delivered to the target site. Alternatives to increase the local concentration of DO
Background: Despite early referral of uraemic patients to nephrological care, suboptimal dialysis initiation (SDI) remains a common problem associated with increased morbimortality. We hypothesized that SDI is related to pre-dialysis care.Methods: In the 'Peridialysis' study, time and reasons for dialysis initiation (DI), clinical and biochemical data and centre characteristics were registered dur
Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional treatment strategies. In this study, we used a calcium sulphate hemihydrate (CSH)/nanohydroxyapatite (nH
Background: High expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate, with prolonged survival in several malignant diseases and with the benefit of platinum-based chemotherapy in ovarian cancer. The aim of this study was to evaluate RBM3 in metastatic colorectal cancer (mCRC) as a prognostic factor for overall survival and in relation to benefit of first-line chemother
Background: It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF. Methods and Results: In this nationwide study of the Swedish population, patients with AF and t
Objective: Atherosclerosis is characterized by accumulation of lipids, cells and extracellular matrix (ECM) proteins in the arterial wall. Collagen type I (COL1), a component of the arterial ECM, is cleaved by matrix metalloproteinases (MMPs) and known to be remodelled in atherosclerosis. We explored whether the MMP-mediated COL1 biomarker, C1M, was associated with cardiovascular events, cardiovas
LL_SMMS10_prel160802 Reading list for Service Management: Theory – Development and Traditions, 15 hp, SMMS10. Preliminary version Book about writing literature reviews, ca 200 pages Choose one of four: Hart, C (1998) Doing a literature review: releasing the social science research imagination, Sage: London. 230 pp. Jesson, J; Matheson, L & Lacey, F.M (2011) Doing your literature review: traditio
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/ll_smms10_prel160802_0.pdf - 2026-07-17
Syllabus SMMX15 Introduction to Sustainability This is a translation of the syllabus which was established in Swedish. Faculty of Social Sciences SMMX15, Introduction to Sustainability, 7.5 credits Introduktion till hållbarhet, 7,5 högskolepoäng Second Cycle / Avancerad nivå Details of approval The syllabus was approved by the board of the Department of Service Management and Service Studies on 20
https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2026-01/Kp_SMMX15_eng_HT26_251023_1.pdf - 2026-07-17
Mass migrations are a phenomenon of all times. Notably, following the Second World War, there have been huge migration movements and decolonisation processes, particularly by the Germans and the Jews, but also by Roma and other groups. Parallel to that, in 1963, Protocol No. 4 to the Convention was signed, with Article 4 prohibiting the collective expulsion of aliens. In 2020, 3,6% of the populati
This thesis takes its starting point in the Green Paper on the Modernisation of EU Public Procurement Policy Towards a More Efficient European Procurement Market, in which the Commission made interesting remarks concerning the interlinks between the Union’s 2020 Strategy, public procurement and State aid. Assessing these interlinks have been an objective of this thesis. As for public procurement a
Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on
