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OBJECTIVE: To compare neurofilament light (NfL) and tau as blood-based biomarkers for acute sports-related concussion (SRC) and determine whether their concentrations at different time points after the injury are associated with prolonged time to return to play (RTP).METHODS: A total of 288 professional hockey players were followed longitudinally from September 1, 2012, to April 30, 2015. Data col
Purpose City logistics projects often include urban consolidation centres (UCCs) to reduce the environmental impact of transportation by consolidating the goods flow in cities. However, there is limited knowledge about the actual environmental effects of such consolidation, e.g. in terms of number of vehicles in a city and the congestion, nuisances and emissions. The purpose of the paper is to mea
Over the past decade, the number of ongoing bike-sharing programs has remarkably risen. In this framework, operators need appropriate methodologies to support them in optimizing the allocation of their resources to globally enhance the bike-sharing program, even without massive and costly interventions on the existing configuration of the system. In this paper, we propose an optimization model abl
Free-floating bike sharing systems are an emerging new generation of bike rentals, that eliminates the need for specific stations and allows to leave a bicycle (almost) everywhere in the network. Although free-floating bikes allow much greater spontaneity and flexibility for the user, they need additional operational challenges especially in facing the bike relocation process. Then, we suggest a m
The objective of this thesis is to investigate the synthesis of well-defined polymer nanohybrid materials bearing desirable functionality via surface-initiated atom transfer radical polymerization (SI-ATRP) for potential bioapplications.SI-ATRP is an excellent controlled radical polymerization (CRP) method for the synthesis of polymer nanohybrid by growing polymer brushes (chains) from an interfac
Objective: We endeavored to create a comprehensive course in global surgery involving multinational exchange. Design: The course involved 2 weeks of didactics, 2 weeks of clinical rotations in a low-resource setting and 1 week for a capstone project. We evaluated our success through knowledge tests, surveys of the students, and surveys of our Zimbabwean hosts. Setting: The didactic portions were h
1. IntroductionThe third wave of biotechnology – white biotechnology – started with the end of the 20th century with the goal to replace conventional chemical processes based on C2/C3 chemistry by biotechnological processes. In biotechnology fermentation is used as standard conversion process for the production of bulk fermentation products such as antibiotics, enzymes, bioethanol and organic acid
Objective: Zea m1 is one of the most common aeroallergens, causing allergy. This pollen allergen, present in maize, is responsible for type I hypersensitivity reaction. Despite having available X ray crystal structure of this pollen allergen, no definite vaccine has been developed for allergic disorder in humans. Method: In our present study, an epitope-based peptide vaccine against Zea m 1 pollen
Fuzzy approaches in a low-level image processing method to partition the homogeneous regions are important challenges in image segmentation. The analysis of the fuzziness in data produces comparable or improved solutions compared with the respective crisp approaches. The novel approach proposed in this chapter has been found to enhance the functionality of the fuzzy rule base and thus enhance the
An important approach for image classification is the clustering of pixels in the spectral domain. Fast detection of different land cover regions or clusters of arbitrarily varying shapes and sizes in satellite images presents a challenging task. In this article, an efficient scalable parallel clustering technique of multi-spectral remote sensing imagery using a recently developed point symmetry-b
Genome scans for quantitative trait loci (QTL) in farm animals have concentrated on primary production and health traits, and information on QTL for other important traits is rare. We performed a whole genome scan in a granddaughter design to detect QTL affecting body conformation and behavior in dairy cattle. The analysis included 16 paternal half-sib families of the Holstein breed with 872 sons
„White biotechnology“- the third and latest wave of biotechnology - is aiming to replace the well-established C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. One of the key concepts related to “white biotechnology” are so
The notion of warping the rate of time is explored in the context of differentially flat systems to enable time-optimal motion by convex optimisation. Examples are given with systems configured on the special Euclidean groups SE(2) and SE(3), with and without differential constraints. The proposed method complements classical methods of motion planning, may be used in a real-time context with guar
IntroductionIncreasing oil prices and growing environmental concerns in recent years have driven the development of renewable biofuels. Stimulated by this, the European production of bioethanol, which is produced by fermentation of sugar components in biomass, has nearly doubled in the last two years increasing from 913 million litres in 2005 to 1,565 million litres in 2006. The continuation of
Our everyday experiences show that the lack of needed information in various human affairs may give rise to consequences that we would like to avoid – e.g. the 2004 Tsunami in Southeast Asia. However, we still do not have a coherent theoretical body that addresses such experiences of information inadequacy as this changes everything in respect to the current conception of the information society,
Objectives: Constant infusion lumbar infusion test (LIT) is an important way to find which patients, of those with signs and symptoms corresponding to normal pressure hydrocephalus (NPH) who will improve from shunt operation. LIT is a stress test on the ability for cerebrospinal fluid re-absorbtion. The aim of this study is to show how the information from LIT can be improved by quantitative analy
