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Identification of human glycosyltransferase genes expressed in erythroid cells predicts potential carbohydrate blood group loci

Glycans are biologically important structures synthesised by glycosyltransferase (GT) enzymes. Disruptive genetic null variants in GT genes can lead to serious illness but benign phenotypes are also seen, including antigenic differences on the red blood cell (RBC) surface, giving rise to blood groups. To characterise known and potential carbohydrate blood group antigens without a known underlying

Hospital differences in mortality rates after hip fracture surgery in Denmark

Background: Thirty-day mortality after hip fracture is widely used when ranking hospital performance, but the reliability of such hospital ranking is seldom calculated. We aimed to quantify the variation in 30-day mortality across hospitals and to determine the hospital general contextual effect for understanding patient differences in 30-day mortality risk. Methods: Patients aged ≥65 years with a

Dietary Pattern Specific Protein Biomarkers for Cardiovascular Disease : A Cross-Sectional Study in 2 Independent Cohorts

Background: Mechanisms related to the influence of diet on the development of cardiovascular disease are not entirely understood, and protein biomarkers may help to understand these pathways. Studies of biomarkers identified with multiplex proteomic methods and dietary patterns are largely lacking. Methods and Results: Dietary patterns were generated through principal component analysis in 2 popul

Transport dynamics of droplet impact on the wedge-patterned biphilic surface

Droplet impact on biphilic surfaces with a wettability contrast has been intensively studied in recent years. In this work the effects of tilting and apex angles on droplet transport dynamics after impacting on a wedge-patterned biphilic surface at low Weber numbers were investigated experimentally. The biphilic surface was fabricated by applying a hydrophobic polymer coating on a bare silicon sur

Heat Transfer in Aerospace Applications

DescriptionHeat Transfer in Aerospace Applications is the first book to provide an overall description of various heat transfer issues of relevance for aerospace applications. The book contains chapters relating to convection cooling, heat pipes, ablation, heat transfer at high velocity, low pressure and microgravity, aircraft heat exchangers, fuel cells, and cryogenic cooling systems.Chapters spe

Impaired kidney function is associated with lower cognitive function in the elder general population. Results from the Good Aging in Skåne (GÅS) cohort study

Background: A possible connection on vascular basis between impaired kidney function and cognitive dysfunction has been suggested in previous studies. Contradictory results regarding specific cognitive domains have been reported. The aim for this study was to investigate the association between kidney function and specific cognitive domains. Methods: In this cross-sectional design, data from the g

Magnetic Guinier law

Small-angle scattering of X-rays and neutrons is a routine method for the determination of nanoparticle sizes. The so-called Guinier law represents the low-q approximation for the small-angle scattering curve from an assembly of particles. The Guinier law has originally been derived for nonmagnetic particle-matrix-type systems and it is successfully employed for the estimation of particle sizes in

High Plasma Erythropoietin Predicts Incident Fractures in Elderly Men with Normal Renal Function : The MrOS Sweden Cohort

Preclinical studies on the role of erythropoietin (EPO) in bone metabolism are contradictory. Regeneration models indicate an anabolic effect on bone healing, whereas models on physiologic bone remodeling indicate a catabolic effect on bone mass. No human studies on EPO and fracture risk are available. It is known that fibroblast growth factor 23 (FGF23) affects bone mineralization and that serum

Third-trimester prediction of successful vaginal birth after one cesarean delivery—A Swedish model

Introduction: The objective was to create a clinically useful prediction model for vaginal birth in trial of labor after one cesarean section, appropriate for a third trimester consultation. Material and methods: Women with one cesarean section and at least one following delivery (N = 38 686) in the Swedish Medical Birth Register, 1998-2013, were studied. The women were randomly divided into one d

Experimental and numerical study of natural convection in bottom-heated cylindrical cavity filled with molten salt nanofluids

This paper combines numerical and experimental to study the heat transfer by free convection for nanofluids of molten salt within a cavity with cylindrical shape which is heated at the bottom and releases heat at the top. The aim is to acquire the free convection laws for nanofluids of molten salt in a cylindrical cavity. It is found that after adding nanoparticles, the molten salts have lower vis

Study of effects of axisymmetric endwall contouring on film cooling/heat transfer and secondary losses in a cascade of first stage nozzle guide vane

The film cooling and heat transfer on the endwall especially in the junction region of a vane/blade which encounters strong vortical flow is of great significance in turbomachinery. Achievement of excellent film cooling and aerodynamic performance by controlling the secondary flow in that region can lead to increased gas turbine efficiency. This study investigates axisymmetric endwall contouring p

Relationships Between Frequency of Moderate Physical Activity and Longevity : An 11-Year Follow-up Study

Objectives: Moderate physical activity gains survival. There are, however, several variables that may affect this relationship. In this study, the relationship between moderate physical activity and longevity was investigated, taking into account age, gender, smoking habits, cohabitation status, body mass index, leg strength and balance, education level and cognitive function. Method: A sample of

A 9-Year Follow-Up of Women and Men Reporting Pain: Results from The Swedish National Study Of Aging And Care - Blekinge

Background and aim: Pain is common in older adults, but its relationship with ageing is unclear. The aim was toinvestigate pain among adults aged 72 years and older by means of a population-based sample followed for aperiod of nine years.Methods: The Swedish National study on Aging and Care (SNAC) is conducted at four research centres. AtSNAC-Blekinge (B), 609 (60.6%) women and 396 (39.4%) men wer