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The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study

Summary: In this prospective study in Swedish elderly men, PAD based on an ABI < 0.9 was associated with an increased risk of hip fracture, independent of age and hip BMD. However, after further adjustments for comorbidity, medications, physical function, and socioeconomic factors, the association diminished and was no longer statistically significant. Introduction: To examine if peripheral arteri

Folding lattice proteins with quantum annealing

Quantum annealing is a promising approach for obtaining good approximate solutions to difficult optimization problems. Folding a protein sequence into its minimum-energy structure represents such a problem. For testing new algorithms and technologies for this task, the minimal lattice-based [hydrophobic (H) or polar (P) beads] HP model is well suited, as it represents a considerable challenge desp

Research priority setting in emergency care : A scoping review

Objective: Priority areas for emergency care research are emerging and becoming ever more important. The objectives of this scoping review were to (1) provide a comprehensive overview of published emergency care priority-setting studies by collating and comparing priority-setting methodology and (2) describe the resulting research priorities identified. Methods: The Joanna Briggs Institute methodo

Managing exploration and exploitation in construction projects : Nordic Conference on Construction Economics and Organization : 12/06/2013 - 14/06/2013

Prior research has shown that companies in various industrial contexts need to achieve both exploitation of current knowledge and technologies to make profits today, and exploration of new knowledge and technologies to adapt to changing conditions and prepare for tomorrow’s demands. The capacity to achieve both exploration and exploitation is especially problematic in project based organizations d

Nuclear spin interactions and coherent control in rare-earth-ion-doped crystals for quantum computing

This thesis work concerns studies of two rare-earth-ions, praseodymium (Pr3+) and europium (Eu3+), doped into a yttrium orthosilicate (Y2SiO5) crystal for applications in quantum computing. The nuclear spin levels of these ions can have very long coherence times, up to several hours. Coherence can also be effectively transferred between the optical and hyperfine levels. These systems, therefore, h

Effectiveness of the BNT162b2 mRNA Vaccine Compared with Hybrid Immunity in Populations Prioritized and Non-Prioritized for COVID-19 Vaccination in 2021–2022 : A Naturalistic Case-Control Study in Sweden

The term hybrid immunity is used to denote the immunological status of vaccinated individuals with a history of natural infection. Reports of new SARS-CoV-2 variants of concern motivate continuous rethought and renewal of COVID-19 vaccination programs. We used a naturalistic case-control study design to compare the effectiveness of the BNT162b2 mRNA vaccine to hybrid immunity 180 days post-vaccina

Från vitterhet till vetenskap : En studie över Kungl. Vetenskapsakademiens lärdomsklass under 1800-talet

In 1798 the Royal Academy of Science instituted a classification of its members, designating the last class to be filled by those engaged with world of learning and beautiful arts. This study maps the population of this “erudite class” and analyzes the negotiation of epistemic virtues and merits linked to the nebulous field from which the class drew its members. The article argues that a previous

Prevalence and factors associated with faecal carriage of extended-spectrum β-lactamase-producing Enterobacterales among peripartum women in the community in Cambodia

BACKGROUND: In Southeast-Asia, where many conditions associated with dissemination of ESBL-producing Enterobacterales (ESBL-E) in the community are met, data from the community are scarce but show high ESBL-E carriage prevalence. Maternal ESBL-E colonization is considered a risk factor for neonatal colonization, which is the first step towards developing neonatal sepsis. Despite this, ESBL-E carri

Activity patterns throughout the annual cycle in a long-distance migratory songbird, the red-backed shrike Lanius collurio

Background: Long-distance migratory birds undergo complex annual cycles during which they must adjust their behaviour according to the needs and conditions encountered throughout the year. Yet, variation in activity throughout the entire annual cycle has rarely been studied in wild migratory birds. Methods: We used multisensor data loggers to evaluate the patterns of activity throughout the comple

Targeted proteomics identifies potential biomarkers of dysglycaemia, beta cell function and insulin sensitivity in Black African men and women

Aims/hypothesis: Using a targeted proteomics approach, we aimed to identify and validate circulating proteins associated with impaired glucose metabolism (IGM) and type 2 diabetes in a Black South African cohort. In addition, we assessed sex-specific associations between the validated proteins and pathophysiological pathways of type 2 diabetes. Methods: This cross-sectional study included Black So

Transition Towards Sustainable E-Commerce: A Design Thinking Approach

AimTo achieve the sustainable development goals there is no doubt that we need to transform e-commerce into a sustainable system. Individual efforts are not enough. We need changes at the system level. We also know that research and innovation are crucial for tackling this global and complex societal challenge. How do we transform e-commerce into a sustainable system? What key areas and issues nee

Towards Single-Ion Detection and Single-Photon Storage in Rare-Earth-Ion-Doped Crystals

Solid materials doped with rare-earth ions are considered an attractive platform for quantum information applications. One of the main reasons for this is the exceptionally long optical and hyperfine coherence times of the 4fn states, due to the shielding provided by the outer lying 5s and 5p electrons. This enables a large number of quantum operations before the system loses its coherence. Anothe

Digitaliseringen av svenskt tryck : Massdigitalisering, kritisk digitalisering och frågan om hur man skapar en representativ korpus

The Swedish National Library published together with the university libraries in Gothenburg, Lund, Stockholm, Umeå and Uppsala in January 2020 a Declaration of Intent where the goal to digitiz Swedish print from the 15th century until today was formulated. Based on this objective, the article discusses different digitization strategies in libraries. Mass digitization stands for the rapid digitizat

Generation, characterization and application of infrared few-cycle light pulses

In recent decades, laser systems emitting pulses of light containing only a few electric field oscillations under their envelope have become common in many ultrafast optics laboratories. Owing to unique temporal characteristics and achieving extreme field strengths, these so-­called few­-cycle pulses have been instrumental in unlocking new regimes of light-­matter interaction.The work presented in

The Evolution of Capabilities Underpinning Business Model Innovation for Sustainability in Large Incumbent Firms

Many studies in traditional business model (BM) literature acknowledge that it is hard for incumbent firms to change their business models, a finding echoed in the business model innovation for sustainability (BMIfS) literature. Large incumbent firms often lack or have weak capabilities needed for sustainability-driven business model innovation. This paper addresses how capabilities for such innov

Where did the finch go? Insights from radio telemetry of the medium ground finch (Geospiza fortis)

Movement patterns and habitat selection of animals have important implications for ecology and evolution. Darwin's finches are a classic model system for ecological and evolutionary studies, yet their spatial ecology remains poorly studied. We tagged and radio-tracked five (three females, two males) medium ground finches (Geospiza fortis) to examine the feasibility of telemetry for understanding t

Seasonal variations in sleep duration and sleep complaints : A Swedish cohort study in middle-aged and older individuals

Subjective sleep reports are widely used research tools in epidemiology. Whether sleep reports can differ between seasons is less clear. Using multivariable binary or multinomial logistic regression analyses, in the present Swedish cross-sectional two-centre cohort study (N = 19,254; mean age 61 years), we found that participants surveyed during the summer (June–August) were more likely to report