Sökresultat

Inom läkemedelssektorn, originalföretagen som investerar stora summor pengar i forskning och utveckling av nya läkemedel vanligtvis söker patent för flera skyddsområden. De försöker utnyttja det monopol ett patent ger för att skydda sina egna originalläkemedel mot generiska läkemedels marknadsinträde och utebliven vinst som det för med sig. Generiska företag för att kunna lansera sina generiska prIn the pharmaceutical sector, originator companies that invest large sum of money in R&D of new medicines usually file patent applications for several areas of protection. They try to take advantage of a monopoly that a patent grants to protect their medicines against generic entry on the market and consequently the loss of profits. Generic companies in order to be able to launch their generic

The European furniture industry is driven to change from linear to circular business models. Product-service systems (PSS) are considered to offer promising solutions that may enable the transition towards the circular economy. In the furniture industry, one example of a product-service system is the furnishing rental service. However, understanding of how such a service could be developed and imp

Studiens syfte är att undersöka hur flöjtpedagoger yrkesverksamma på kulturskolor i Sverige beskriver sin undervisning med fokus på utveckling av det flöjtistiska hantverket hos nybörjare. Forskningsfrågorna som besvaras är: Vilket/vilka mål har flöjtpedagogerna med sin undervisning? Vilka flöjtistiska byggstenar anser flöjtpedagogerna vara nödvändiga att grundlägga hos nybörjarna? Hur arbetar flöThe aim of this study is to examine how flute teachers, working in the municipal Swedish music schools, describe the music education, focusing on the development of the beginner's technical skills of flute playing from a hermeneutic point of view. The research questions are: What are the flute teachers´ aims of their teaching? What basic skills of flute playing do they consider as important in

Water for firefighting is often associated with drinking water, due to fire hydrants. Fire hydrants have been installed in towns for a long time and are one of the most common ways for the rescue service to get hold of water for extinguishing fires. This report evaluates the ways that the rescue service uses their water and how the get continuously water to the fire site. Other extinguishing metho

Inte bara potthål och andra korta gupp, utan även mycket långa ojämnheter på vägbanan skapar stora dynamiska laster då tunga fordon färdas där. Dessa laster skadar vägbanan och gör att slitaget ökar så att livslängden på vägbanan förkortas. Detta leder i sin tur till att kostnaden för att hålla vägbanan i acceptabelt skick ökar. Syftet med detta examensarbete är pröva en metod för att beräkna och

Brandskum som innehåller per- och polyfluorerade ämnen (PFAS), på engelska Aqueuous Film Forming Foam (AFFF), är en av de främsta källorna till föroreningarna i Sverige. Grundvattenförorening orsakat av användandet av AFFF under brandövningar har undersökts i Kallinge, Blekinge. I området har grundvattnet använts som råvatten vilket resulterat i förhöjda halter av PFAS i dricksvattnet. Liknande faAqueuous Film Forming Foam (AFFF) containing Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) is one of the major sources of groundwater contamination in Sweden. Groundwater contamination caused by the use of AFFF in correlation to fire training events was investigated in Kallinge, Sweden. At the site groundwater was previously used as a drinking water source consequently affecting the inhabit

Although prior falls are a well-established predictor of future fracture, there is currently limited evidence regarding the specific value of falls history in fracture risk assessment relative to that of other clinical risk factors and bone mineral density (BMD) measurement. We therefore investigated, across the three Osteoporotic Fractures in Men (MrOS) Study cohorts, whether past falls predicted

Objectives To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. Design Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. Setting 25 cohorts from Europe, United States, east Asia, and Australia with genome wide genotyping and fracture data. Participants A discover

Dyspnea is a common and highly distressing symptom in patients with advanced illnesses. Many patients continue to experience chronic dyspnea despite optimal management of underlying disease(s) and various non-pharmacologic interventions, necessitating the consideration of pharmacologic therapies for palliation of dyspnea. One commonly asked question by clinicians is whether benzodiazepines have a

BACKGROUND: Given the limited research focusing on psychotherapeutic interventions for suicide attempters, it is noteworthy that the Attempted Suicide Short Intervention Program (ASSIP) has demonstrated promising results in previous studies. In this investigation, we aim to evaluate the effectiveness of ASSIP across diverse healthcare settings, outlining the study design and planned evaluation.MET

Recently, dimpled surfaces have found great attention due to their abilities in energy management and heat transfer enhancement, low weight, small values of pressure drop penalty, simple fabrication, and small maintenance costs. Many experimental and numerical studies are accomplished to investigate the potentials of dimpled surface technology in energy management of various thermal energy systems

Fatal intoxications with opioids are known to be associated with an increased lung weight, as well as with brain and pulmonary edema and urinary retention. However, there is evidence to suggest that fatal intoxications with non-opioid substances are also associated with increased lung weight; however, the latter aspect has not been comprehensively analyzed. To determine to what extent opioid and n

The pandemic of chronic non-communicable diseases (NCDs) poses substantial challenges to the health financing sustainability in high-income and low/middle income countries (LMICs). The aim of this review is to identify the bottle neck inefficiencies in NCDs attributable spending and propose sustainable health financing solutions. The World Health Organization (WHO) introduced the "best buy" concep

INTRODUCTION: This study examines the link between daytime and nighttime excessive sleep and cognition, cognitive decline, and dementia in individuals with existing mild cognitive impairment (MCI).METHODS: Using data from the Swedish longitudinal study Good Aging in Skåne, participants aged 60-102 years were retrospectively classified as MCI based on cognitive testing. The average follow-up time w

Summary: Screening initiatives for osteoporosis must facilitate treatment of those at elevated fracture risk. In a randomized controlled trial of 24,229 women, those in the screening group with FRAX ≥ 15% were invited for DXA with AOM treatment offered as per national guidelines. Treatment initiation in the following year was 9.5 times higher compared with controls. Purpose: To determine if screen

Background: Eosinophil-derived neurotoxin (EDN), an eosinophil granule protein, is a candidate biomarker in asthma to reflect eosinophilic activation. Objective: We sought to characterize the distribution of serum and nasal lavage fluid (NLF) EDN levels in different adult population subgroups and assess the determinants of high EDN levels. Methods: Serum and NLF samples were collected from a popul

BackgroundLow- and middle-income countries (LMICs), including Bangladesh, are experiencing a nutritional transition characterized by rising unhealthy food consumption (UFC), which increases the risk of nutrient deficiencies and chronic diseases in children. Despite this concern, research on UFC among Bangladeshi children aged 6–23 months is limited. Therefore, this study aims to estimate the preva

IntroductionUse of long-term oxygen therapy (LTOT) for more than 15 h per day does not reduce mortality or hospitalizations, but may increase the risk of adverse events. We evaluated the relationship between daily oxygen use duration and adverse events, symptoms, and health status in patients on LTOT.MethodsThis was a cross-sectional survey study of a random sample (N = 650) of adults with ongoing

OBJECTIVE: To qualitatively explore the perceptions of Para athletes, coaches and stakeholders of the implementation, use and effects of the health promotion intervention 'Safe and Healthy Para sport' (SHAPE). A secondary aim was to explore participants' perceptions of how safety and health in Para sport could be further developed.METHODS: As part of a process evaluation, this qualitative, descrip