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Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(OH)D concentration is causally associated with blood pressure and hypertension risk.
Aim To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. Methods A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitants) participate in a National survey of out of hospital cardiac arrest. Results I
This article gives an overview of some ethical problems raised in connection to nutritional genomics, especially the use of knowledge from nutrigenomics as a basis for personalised nutrition after a genetic test.
The incidence of hip fracture in Sweden is substantially lower in immigrants than in the population born in Sweden. Thus, the use of a FRAXA (R) model in immigrants overestimates the risk of fracture, and the use of country of origin-specific models may be more appropriate. Introduction Age-specific fracture and mortality rates vary between countries so that FRAX tools are country-specific. In the
In elderly man, low serum 25-hydroxyvitamin D (25(OH)D) was associated with a substantial excess risk of death compared to 25(OH)D values greater than 50-70 nmol/l, but the association attenuated with time. The aim of the present study was to determine whether poor vitamin D status was associated with an increase in the risk of death in elderly men. We studied the relationship between serum 25(OH)
Postmenopausal women consistently have higher phosphorus levels than similarly aged men. As it is known that estradiol induces phosphaturia in rodents, we evaluated the cross-sectional association of sex hormones with serum phosphorus in 1346 community-living older men (mean age 76) of which 18% had moderate (stage 3) kidney disease. Using linear regression with serum phosphorus levels as the depe
BackgroundLow- and middle-income countries (LMICs), including Bangladesh, are experiencing a nutritional transition characterized by rising unhealthy food consumption (UFC), which increases the risk of nutrient deficiencies and chronic diseases in children. Despite this concern, research on UFC among Bangladeshi children aged 6–23 months is limited. Therefore, this study aims to estimate the preva
IntroductionUse of long-term oxygen therapy (LTOT) for more than 15 h per day does not reduce mortality or hospitalizations, but may increase the risk of adverse events. We evaluated the relationship between daily oxygen use duration and adverse events, symptoms, and health status in patients on LTOT.MethodsThis was a cross-sectional survey study of a random sample (N = 650) of adults with ongoing
Youth are one of the nine major groups of civil society for sustainable development formalized by Agenda 21. The Major Group of Children and Youth is an active independent mechanism facilitating youth involvement in the United Nations system. Youth representatives from various organizations increasingly engage in global sustainability politics but face challenges such as financial constraints, tok
OBJECTIVE: To qualitatively explore the perceptions of Para athletes, coaches and stakeholders of the implementation, use and effects of the health promotion intervention 'Safe and Healthy Para sport' (SHAPE). A secondary aim was to explore participants' perceptions of how safety and health in Para sport could be further developed.METHODS: As part of a process evaluation, this qualitative, descrip
This A-Z Guide offers an accessible and user-friendly overview of the essential concepts and terms needed to understand the implementation of the SDGs. Crafted in the form of an encyclopaedia, the volume presents 105 entries on important concepts and terms and their links to academic and policy debates. Each entry offers basic definitions of the concept or term at issue, followed by a brief discus
Background and purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by progressively destructive polyarthritis. Key autoimmune features include the presence of autoantibodies. The purpose of this review is to discuss the diagnostic and prognostic properties of rheumatoid factor (RF) and anti-citrullinated protein/peptide antibodies (ACPA), based on current use in Swe
Introduction Cluster analysis, a machine learning-based and data-driven technique for identifying groups in data, has demonstrated its potential in a wide range of contexts. However, critical appraisal and reproducibility are often limited by insufficient reporting, ultimately hampering the interpretation and trust of key stakeholders. The present paper describes the protocol that will guide the d
BackgroundEndostatin is a promising biomarker for predicting acute kidney injury (AKI) and mortality in the intensive care unit (ICU). We investigated plasma endostatin levels at ICU admission as predictors of new-onset AKI within 48 h after ICU admission, renal replacement therapy (RRT) within 7 days after ICU admission, and 30-day mortality.MethodsA retrospective multicentre study was performed
In the present study, copper surfaces were deposited with Cu-Zinc nanoparticles of 0.6 mg by an electrophoretic deposition method (EPD). Two deposition patterns were designed, i.e., fully deposition (EPD-F) and channel-pattern deposition (EPD-C). In the channel-pattern deposition, the smooth channel and the deposition channel occur alternatively, by keeping the width of the smooth channel as 3 mm,
I ett samhälle med ökad globalisering blir regler angående den internationella privat- och processrätten allt viktigare. Denna uppsats behandlar lagvalsregler, vilka går att finna i Romkonventionen. Romkonventionens huvudregel är lagvalsfrihet. Det finns dock bestämmelser i konventionen som inskränker denna möjlighet. Artikel 7 rörande internationellt tvingande regler är ett exempel på detta och ä
The interferon inducible protein TRIM22 has been identified as a p53 target gene, with possible involvement in proliferation and differentiation of leukaemia cells. Here, the expression levels of TRIM22 during haematopoietic differentiation are characterised. Expression of TRIM22 correlates inversely to differentiation, as TRIM22 is highly expressed in CD34(+) human bone marrow progenitor cells, b
Background and aims: In the elderly, balance and walking impairments are assumed to play an important role in causing falls. We have assessed prospectively the predictive ability of health, function and balance variables regarding falls and their location. Methods: Falls which occurred during one year in a random sample of 307 women aged 75 years and over (mean 80.8 years, response rate 74.5%) liv
