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This study presents a novel application of multivariate iterative learning control (ILC) to the continuous, chromatographic ion-exchange purification of biopharmaceuticals for consistent and reliable production. The ILC algorithm used was based on a linearized model of the retention times of two compounds as functions of the starting and ending values of a linear salt gradient. Simulations of an i

In this article, we propose a novel solution to detect multiple targets using a distributed multiple-input multiple-output (MIMO) radar under the so-called 'defocused transmit-defocused receive' operating mode. The proposed method employs a grid-based data matching algorithm, aiming to associate the target responses to potential target locations, solving the resulting data puzzle that evaluates th

Methods for inference and simulation of linearly constrained Gaussian MarkovRandom Fields (GMRF) are computationally prohibitive when the number ofconstraints is large. In some cases, such as for intrinsic GMRFs, they may even beunfeasible. We propose a new class of methods to overcome these challenges in the common case of sparse constraints, where one has a large number of constraints and each o

Om måluppfyllelse ska kunna säkerställas för alla studenter behöver förutsättningar ges för lärandeprogression mot utbildningens mål. För att stärka dessa förutsättningar har progressionsplaner utvecklats för de naturvetenskapliga utbildningarna vid Lunds universitet. Progressionsplanen konkretiserar varje examensmål i etappmål med gradvis ökade krav och ger därigenom en överblick över den förvänt

Conservation properties of iterative methods applied to implicit finite volume discretizations of nonlinear conservation laws are analyzed. It is shown that any consistent multistep or Runge-Kutta method is globally conservative. Further, it is shown that Newton’s method, Krylov subspace methods and pseudo-time iterations are globally conservative while the Jacobi and Gauss-Seidel methods are not

Freight transport in urban areas needs to become more sustainable. There is much potential to reduce emissions by transitioning to electric freight vehicles (EFVs). The context of this study is Sweden, a country with ambitious goals for transitioning to fossil-free road transport that incentivizes the adoption of EFVs through regulations, subsidies and environmental zones. However, it seems that f

Leptons with essentially the same properties apart from their mass are grouped into three families (or flavours). The number of leptons of each flavour is conserved in interactions, but this is not imposed by fundamental principles. Since the formulation of the standard model of particle physics, the observation of flavour oscillations among neutrinos has shown that lepton flavour is not conserved

This paper introduces the first minimal solvers that jointly estimate lens distortion and affine rectification from the image of rigidly-transformed coplanar features. The solvers work on scenes without straight lines and, in general, relax strong assumptions about scene content made by the state of the art. The proposed solvers use the affine invariant that coplanar repeats have the same scale in

In this paper, we propose a novel 3-DOF visual odometry method to estimate the location and pose (yaw) of a mobile robot when the robot is navigating indoors. Particularly, we mainly aim at dealing with the corridor-like scenarios where the RGB-D camera mounted on the robot can capture apparent planar structures such as floor or walls. The novelties of our method lie in two-folds. First, to fully

In contrast to artificial systems, animals must forage for food. In biology, the availability of energy is typically both precarious and highly variable. Most importantly, the very structure of organisms is dependent on the continuous metabolism of nutrients into ATP, and its use in maintaining homeostasis. This means that energy is at the centre of all biological processes, including cognition. S

Multiple studies have examined the extent to which consumers’ hunger levels predict their food choices and preference patterns. These investigations often involve making binary choices between hedonic foods (e.g., ice cream) that primarily serve to provide sensory pleasure, and utilitarian foods (e.g., bread) that mainly fulfill functional purposes. However, most consumers entering a grocery store

We study steady axisymmetric water waves with general vorticity and swirl, subject to the influence of surface tension. This can be formulated as an elliptic free boundary problem in terms of Stokes' stream function. A change of variables allows us to overcome the generic coordinate-induced singularities and to cast the problem in the form “identity plus compact,” which is amenable to Rabinowitz's

Fakulteten noterar att förslag nu läggs – mer än ett år försenat – för genomförande av direktivet, men att ny lagstiftning inte avser att träda i kraft förrän den 1 juli 2002. Det är alltid beklagligt med förseningar i genomförandet av central gemenskapslagsstiftning. Utrymmet för den svenske lagstiftaren att skapa egna nya lösningar begränsas av det detaljerade direktivet. Sverige måste uppfylla

Past studies have repeatedly demonstrated the technical feasibility to produce polyhydroxyalkanoate (PHA) using bacterial biomass of mixed microbial cultures (MMCs). Commercial quality grades of poly(3-hydroxybutyrate-co-3-hydroxyvalerate), PHBV, can be produced with control of average monomer composition. However, demonstration of PHBV production and recovery with quality control of molecular wei