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Culturing and patch clamping of Jurkat T cells and neurons on Al 2 O 3 coated nanowire arrays of altered morphology

Nanowire substrates play an increasingly important role for cell cultures as an approach for hybrid bio-semiconductor junctions. We investigate Jurkat T cells and neurons from mice cultured on Al 2 O 3 coated ordered and randomly distributed nanowires. Cell viability was examined by life/membrane staining reporting comparable viability on planar and nanowire substrates. Imaging the hybrid inter

Hydrated Electron Generation by Excitation of Copper Localized Surface Plasmon Resonance

Hydrated electrons are important in radiation chemistry and charge-transfer reactions, with applications that include chemical damage of DNA, catalysis, and signaling. Conventionally, hydrated electrons are produced by pulsed radiolysis, sonolysis, two-ultraviolet-photon laser excitation of liquid water, or photodetachment of suitable electron donors. Here we report a method for the generation of

In situ XAS study of the local structure and oxidation state evolution of palladium in a reduced graphene oxide supported Pd(ii) carbene complex during an undirected C-H acetoxylation reaction

In situ X-ray absorption spectroscopy (XAS) investigations have been performed to provide insights into the reaction mechanism of a palladium(ii) catalyzed undirected C-H acetoxylation reaction in the presence of an oxidant. A Pd(ii) N-heterocyclic carbene complex π-stacked onto reduced graphene oxide (rGO) was used as the catalyst. The Pd speciation during the catalytic process was examined by XA

Technology for biocomputational devices based on molecular motors

For many multivariable problems there are no efficient algorithms for finding solutions. To this day, conventional electronic computers mainly solve problems in a sequential manner. This sequential operation prevents problem-solving within a reasonable time-frame due to superpolynomial, and sometimes even exponential, time complexities. Developing powerful parallel computation techniques has there

Prevalence of Survival Without Major Comorbidities Among Adults Born Prematurely

Importance: Preterm birth has been associated with cardiometabolic, respiratory, and neuropsychiatric disorders in adulthood. However, the prevalence of survival without any major comorbidities is unknown. Objective: To determine the prevalence of survival without major comorbidities in adulthood among persons born preterm vs full-term. Design, Setting, and Participants: National cohort study of a

Imputing missing data of function and disease activity in rheumatoid arthritis registers : What is the best technique?

Objective To compare several methods of missing data imputation for function (Health Assessment Questionnaire) and for disease activity (Disease Activity Score-28 and Clinical Disease Activity Index) in rheumatoid arthritis (RA) patients. Methods One thousand RA patients from observational cohort studies with complete data for function and disease activity at baseline, 6, 12 and 24 months were sel

Microfluidic Particle Sorting in Concentrated Erythrocyte Suspensions

An important step in diagnostics is the isolation of specific cells and microorganisms of interest from blood. Since such bioparticles are often present at very low concentrations, throughput needs to be as high as possible. In addition, to ensure simplicity, a minimum of sample preparation is important. Therefore, sorting schemes that function for whole blood are highly desirable. Deterministic l

Detecting parity effect in a superconducting device in the presence of parity switches

We present a superconducting device showing a clear parity effect in the number of electrons, even when there is, on average, a single nonequilibrium quasiparticle present and the parity of the island switches due to quasiparticles tunneling in and out of the device at rates on the order of 100 Hz. We detect the switching by monitoring in real time the charge state of a superconducting island conn

Associations between being 'locked-in' and health - an epidemiological study

Objective. The aim of this study was to investigate associations between an individual's level of perceived control over labor market position (locked-in and not locked-in) and self-rated health and psychological well-being. Methods. A representative sample (n = 11,675) of the working population in southern Sweden responded to a questionnaire. Results. Sixty-seven percent of the respondents worked

Radiation Tolerant Nanowire Array Solar Cells

Space power systems require photovoltaics that are lightweight, efficient, reliable, and capable of operating for years or decades in space environment. Current solar panels use planar multijunction, III-V based solar cells with very high efficiency, but their specific power (power to weight ratio) is limited by the added mass of radiation shielding (e.g., coverglass) required to protect the cells

Concept of Extremes in Vascular Aging

With advancing age, changes in the arterial wall contribute to what has been called vascular aging, and in some prematurely affected subjects even early vascular aging (EVA).1–5 Several years ago,1 we listed various components of EVA, including arteriosclerosis, atherosclerosis, and excess vasoconstriction, with their clinical expression: arterial stiffening and increased central pulse pressure, c

Attending Heart School and long-term outcome after myocardial infarction : A decennial SWEDEHEART registry study

Background: The Heart School is a standard component of cardiac rehabilitation after myocardial infarction in Sweden. The group-based educational intervention aims to improve modifiable risks, in turn reducing subsequent morbidity and mortality. However, an evaluation with respect to mortality is lacking. Aims: Using linked population registries, we estimated the association of attending Heart Sch

Risk-Adapted Starting Age of Screening for Relatives of Patients with Breast Cancer

Importance: Breast cancer screening guidelines acknowledge the need for earlier screening for women at increased risk but provide limited guidance for women with a family history of breast cancer. A risk-adapted starting age of screening for relatives of patients with breast cancer may help supplement current screening guidelines. Objective: To identify the risk-adapted starting age of breast canc

The impact of grade inflation on higher education enrolment and earnings

This study examines the consequences of grade inflation at the upper secondary education level on enrolment in higher education and earnings for Sweden. Although grade inflation is unfair and may imply inefficient allocation of human resources, current knowledge of grade inflation effects on individual outcomes is scarce. One explanation is probably the challenge of measuring and estimating causal

Controlled asymmetric photoelectron emission using electron wavepacket interference

Two-color ionization is a powerful method for characterizing light fields and investigating atomic and molecular physics with attosecond sources based on High Harmonic Generation (HHG). Depending on the time duration of the light fields, two main techniques have been established: streaking [1], appropriate in the regime where a single attosecond pulse is generated, and RABBIT, used instead when a

Optical far-field extinction of a single GaAs nanowire towards in situ size control of aerotaxy nanowire growth

A substrate-free approach of semiconductor nanowire growth has been achieved by the aerotaxy technique previously. In this work, we propose an in situ method to monitor the size of nanowires through non-destructive optical-extinction measurements. Our work aims to build a theoretical look-up database of extinction spectra for a single nanowire of varying dimensions. We describe the origin of possi

Filter function of graphene oxide : Trapping perfluorinated molecules

We need clean drinking water, but current water purification methods are not always sufficient. This study examines the binding and binding mechanisms when graphene oxide is used as a filter material for removing perfluorinated substances and trihalomethanes. We use density functional theory calculations to examine the binding of the harmful molecules on graphene oxide. Our results indicate that t

Infrared Photodetectors based on Nanowire Arrays with Embedded Quantum Heterostructures

Optical sensors operating in the infrared range of the electromagnetic spectrum are key components in a variety ofapplications including optical communication, night vision, medical diagnosis, surveillance, and astronomy.Semiconductor nanowires have great potential for realizing broadband infrared photodetectors with excellentresponsivity, low dark current and low noise, and a unique compatibility

Thermodynamic modelling of composition and crystal structure of ternary nanowires

An analytic expression for the composition of a ternary solid material nucleating from a quaternary liquid melt has been derived. This theory has been applied to Au-catalyzed and self-catalyzed, nucleation limited VLS growth of ternary III-V nanowires. Next, the developed model has been applied for the description of the composition dependence of the ZB/WZ polytypism in ternary nanowires.

Tailored emission to boost open-circuit voltage in solar cells

Recently, a lot of research focus has been on how to make solar cells more efficient. One direction is to enhance the open-circuit voltage Voc by optimizing the emission of photons in the cell, where emission is a necessary loss process due to the reciprocity between absorption and emission of light. Here, we performed a Shockley-Queisser detailed balance analysis to predict the benefit of managin