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Background People living with serious respiratory illness experience a high burden of symptoms. This review aimed to determine whether multicomponent services reduce symptoms in people with serious illness related to respiratory disease. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) evaluating multicomponent services that enrolled patients due to sympto

BACKGROUND: Pharmaceutical expenditures (PE) are increasing worldwide raising concerns about sustainability. However, the current price index provides an incomplete picture of this trend due to the rapid introduction of new drugs on the market.OBJECTIVE: The aim of this study is to decompose PE into their components and investigate the development in Sweden from 1990 to 2022.METHODS: The PE index

https://www.svenskpsykiatri.se/wp-content/uploads/2024/12/SP-nr-4-2024-till-hemsidan.pdf

Background In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) testing GET (involving incremental increases in

In this thesis, a microfluidics platform with high-speed imaging system was built to investigate gas-liquid flow in single microchannel and interfacial instability in porous media with microchannel network:The mass transfer of slug flow in the rectangular and square microchannels was experimentally studied by using water as liquid phase and CO2 as gas phase. Depending on flow rates, flow patterns

Gas-liquid displacement in porous media widely exists in many terrestrial/extraterrestrial subsurface resource extraction and utilization applications. The typical fingering displacement during gas invading has been well identified through extensive research efforts. Yet, the evolution of fingering structures after invading breakthrough is rarely reported. Herein, through a joint approach of exper

Prior research has shown that companies in various industrial contexts need to achieve both exploitation of current knowledge and technologies to make profits today, and exploration of new knowledge and technologies to adapt to changing conditions and prepare for tomorrow’s demands. The capacity to achieve both exploration and exploitation is especially problematic in project based organizations d

Recent evidence suggests that targeting S100A9 reduces pathological inflammation in abdominal sepsis. Herein, we investigated the role of S100A9 in neutrophil extracellular trap (NET) formation in septic lung damage. NETs were detected by electron microscopy in the lung and by confocal microscopy in vitro. Stimulation of isolated mouse bone marrow-derived neutrophils with S100A9 triggered formatio

In 1798 the Royal Academy of Science instituted a classification of its members, designating the last class to be filled by those engaged with world of learning and beautiful arts. This study maps the population of this “erudite class” and analyzes the negotiation of epistemic virtues and merits linked to the nebulous field from which the class drew its members. The article argues that a previous

Systemic fungal infections are associated with significant morbidity and mortality, and Candida albicans is the most common causative agent. Recognition of yeast cells by immune cell surface receptors can trigger phagocytosis of fungal pathogens and a pro-inflammatory response that may contribute to fungal elimination. Nevertheless, the elicited inflammatory response may be deleterious to the host

Electrodeposition of metals in templates of nano-porous anodic aluminum oxide (NP-AAO) is a versatile way of fabricating ordered arrays of metal nanowires. Thanks to the self-arranged long-range hexagonal order of the pores, electrodeposition in NP-AAO is an easily scalable bottom-up synthesis route and an attractive alternative to traditional top-down fabrication methods such as electron beam lit

Understanding the impact of the geometry and material composition of electrodes on the survival and behavior of retinal cells is of importance for both fundamental cell studies and neuromodulation applications. We investigate how dissociated retinal cells from C57BL/6J mice interact with electrodes made of vertically-aligned carbon nanotubes grown on silicon dioxide substrates. We compare electrod

Background: Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metabolites potentially associated with multiple cancer types, while also allowing the investigation of cancer type-specific associations. Methods: We analysed targeted metabolomics data

We report on the evolution with the magnetic field and the temperature of the vortex lattice (VL) in fully oxygenated YBa2Cu3O7 as studied by time-of-flight small-angle neutron scattering. Using the High Field Magnet/Extreme Environment Diractometer beamline at Helmholtz-Zentrum Berlin, we have obtained data up to 25.9 T - much higher than data available previously. Our VL structure results are co

Background: Birds that forage while covering distance during migration should adjust traveling behaviors as the availability of foraging habitat changes. Particularly, the behavior of those species that depend on bodies of water to find food yet manage to migrate over changing landscapes may be limited by the substantial variation in feeding opportunities along the route. Methods: Using GPS tracki

Objectives: Acquired brain injury (ABI) has long-lasting effects, and patients and their families require continued care andsupport, often for the rest of their lives. For many individuals living with an ABI disorder, nonpharmacologicalrehabilitation treatment care has become increasingly important care component and relevant for informed healthcaredecision making. Our study aimed to appraise econ

AimTo achieve the sustainable development goals there is no doubt that we need to transform e-commerce into a sustainable system. Individual efforts are not enough. We need changes at the system level. We also know that research and innovation are crucial for tackling this global and complex societal challenge. How do we transform e-commerce into a sustainable system? What key areas and issues nee