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BackgroundCerebral small vessel disease (CSVD) is one of the most important causes of cognitive decline. Only a few previous studies have evaluated lung function measures in relation to brain neuropathological changes, and even less studies on specific lesions and areas that could shed light on mechanisms of CSVD.ObjectiveThe aim was to study the association between lung function and CSVD in the g

Communicating in the Face of Global Crises explores the complex ways organizations and their strategic practices are communicatively constituted in relation to the ethical expectations of global publics.Positioning organizational strategies as communicative accomplishments, an international team of authors redirect attention to the important role of communication in constituting responses to globa

BACKGROUND: Aortic pulse wave velocity (PWV) is an indicator of vascular aging and has proven to be effective in adult cardiovascular risk assessment. To use it in young people to identify those who may be at increased cardiovascular disease risk, reference values need to be determined. The Youth Vascular Consortium is a large, international database which was established to investigate vascular a

Imminent crises and the much-needed transition to a sustainable society bring knowledge about de-implementation to the fore. Using case studies with inspiration from process tracing, and with tools from Charles Tilly’s theory on Durable inequality, we identify mechanisms that generate inequality and counteract the implementation of recovery – and strength-based practices. Our case studies of socia

BACKGROUND: Haemophilus influenzae community-acquired pneumonia (CAP) is common, and it is equally common to Streptococcus pneumoniae in some settings. The purpose of this study was to provide additional data on patients affected by H. influenzae CAP and their outcomes.METHODS: Streptococcus pneumoniae-caused CAP (111 cases) was compared to CAP with H. influenzae (53 cases). Patients were adults (

Community-acquired pneumonia (CAP) is a significant health threat for adults. Although conjugate vaccines have reduced pneumococcal CAP incidence in children, Streptococcus pneumoniae-related CAP remains prevalent among older adults. The nasopharynx acts as a reservoir for S. pneumoniae, yet the interplay between this pathogen and the nasopharyngeal microbiome during and after pneumonia remains po

Attosecond pulses, produced through high-order harmonic generation in gases, have been successfully used for observing ultrafast, subfemtosecond electron dynamics in atoms, molecules and solid state systems. Today’s typical attosecond sources, however, are often impaired by their low repetition rate and the resulting insufficient statistics, especially when the number of detectable events per shot

Background: It is important to identify and evaluate cardiovascular risk factors at an early stage to address them accordingly. Among the younger population, the metabolic syndrome is less common than in older ages. However, each separate metabolic risk factor still has an additive effect on cardiovascular risk factor burden. Non-metabolic risk factors that occur in the younger population include

Multimorbidity, i.e., the presence of two or more long-term health conditions, is challenging for healthcare systems worldwide. A related term is comorbidity. This denotes any condition that has existed or may occur during the clinical course of a patient who has the index disease under study. Moreover, frailty is also inter-related with multimorbidity but represents a distinct clinical concept. F

Rationale: According to the Global Initiative for Obstructive Lung Disease (GOLD), the FEV1/FVC ratio is used to confirm the presence of airflow obstruction in the diagnosis of chronic obstructive pulmonary disease (COPD), whereas FEV1 percent predicted normal value (FEV1%pred) is used for grading its severity. The STaging of Airflow obstruction by the FEV1/FVC Ratio (STAR), and its prediction of

Working from anywhere, often associated with digital nomadism, is a growing trend that blurs the boundaries between work and leisure, with individuals choosing to work from tourist destinations. The phenomenon has caught the attention of academics, who mainly focus on the lifestyle aspects of digital nomadism. However, destination management organizations, as well as the tourism and hospitality in

ObjectiveIndividuals with neurodevelopmental and/or neurocognitive disorders (NNDs) have complex, long-term care needs. In Bangladesh, India, and Pakistan, informal carers shoulder the responsibility and strain of providing care for people with NNDs. Intense care demand, societal and cultural care expectations, and lack of support infrastructure often lead to psychosocial strain in this inadequate

Introduction:Knowledge about long-time residual symptoms, disabilities, and psychological health in complex regional pain syndrome (CRPS) is limited.Objectives:The aim was to evaluate outcome, focusing on physical symptoms, disability, and psychological health, in individuals with CRPS through a cross-sectional survey study.Methods:Individuals with a confirmed diagnosis of CRPS were identified thr

AbstractObjectivesThe aim of this systematic review and meta-analysis was to analyse and summarize studies on the effects of polypharmacy on people living with dementia (PwD). The study aimed to categorize these effects, evaluate the quality of the studies, and estimate the pooled effect sizes of these consequences using meta-analysis.MethodA systematic literature review was conducted following th

INTRODUCTION: Cardiovascular drug use may help prevent dementia; however, current evidence is mixed. Using a case–control design, we investigated the association between duration and combination of multiple cardiovascular drug classes and incident dementia. METHODS: From the Swedish national registers, we included 88,065 incident dementia cases aged ≥ 70 at diagnosis between 2011 and 2016 and 880,

The COVID-19 pandemic put a lot of strain on healthcare organizations. Nurses accountfor over 50% of healthcare staff, and how nurses perform in their work is influenced by a number ofhuman and work environmental factors. However, to our knowledge, there has not been a previousstudy with the intention to look at all areas that affect a sustainable working life and how theseimpact nurses’ mental we