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Swedish Normative Scores for the BREAST-Q Reduction/Mastopexy Module

Background: Norm values for patient reported outcomes, that is knowledge about how the general population of women rate their breast-related satisfaction and quality of life, are necessary to interpret the meaning of scores. The aims of this study were to create Swedish normative values for the BREAST-Q reduction/mastopexy module and to describe what healthy women are most satisfied/dissatisfied w

Fever therapy in febrile adults : systematic review with meta-analyses and trial sequential analyses

Objective: To investigate the effects of fever therapy compared with no fever therapy in a wide population of febrile adults. Design: Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. Data sources: CENTRAL, BIOSIS, CINAHL, MEDLINE, Embase, LILACS, Scopus, and Web of Science Core Collection, searched from their inception to 2 July 2021. Eligibility cr

Analysis of thermal efficiency of a corrugated double-tube heat exchanger with nanofluids

This research investigated convective heat transfer and hydraulic resistance of smooth and corrugated double-tube heat exchangers at various flow rates from 60 L/h to 200 L/h. The inner tube with a thread structure is designed with three pitches, i.e., 4 mm, 6 mm and 8 mm. Nanofluids are used as tube-side fluids to analyze the enhancement of heat transfer on the inner tube side. Results show that

Heat transfer and field synergy characteristics in a rectangular unit channel under mechanical vibration

The internal heat exchangers of a vehicle in driving are excited by forced vibration due to road bumps. But the effect of this phenomenon on the thermal-hydraulic performance of the heat exchanger has not been systematically studied. To investigate the influence of this vibration on the heat transfer characteristics, a numerical model of the rectangular heat exchanger unit channel under vibration

Improved 223Ra Therapy with Combination Epithelial Sodium Channel Blockade

[223Ra]RaCl2 is the first approved a-particle-emitting therapy and is indicated for treatment of bonemetastatic castration-resistant prostate cancer. Approximately half the dose is absorbed into the gastrointestinal tract within minutes of administration, limiting disease-site uptake and contributing to toxicity. Here,we investigated the role of enteric ion channels and their modulation for improv

Energy transfer in multi-funnel systems quantitatively assessed by two-dimensional polarization imaging and single funnel approximation : From single molecules to ensembles

Two-dimensional polarization imaging (2D POLIM) is an experimental method where correlations between fluorescence excitation- and fluorescence emission-polarization properties are measured. One way to analyze 2D POLIM data is to apply a so-called single funnel approximation (SFA). The SFA allows for quantitative assessment of energy transfer between chromophores with identical spectra [homo-FRET (

Circulating Growth Differentiation Factor 15 Levels Are Associated With Risk of Both Intracerebral and Subarachnoid Hemorrhage

Background: Growth differentiation factor 15 (GDF-15) has been associated with the risk of developing major bleedings, including but not restricted to intracranial hemorrhages, in patients on oral anticoagulants or dual antiplatelet therapy. We hypothesized that there may be an association of GDF-15 with incidence of hemorrhagic strokes in the general population, which has not been investigated be

Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers

Importance: Novel plasma biomarkers, especially phosphorylated tau (p-tau), can detect brain tau aggregates in Alzheimer disease. Objective: To determine which plasma biomarker combinations can accurately detect tau pathological brain changes in Down syndrome (DS). Design, Setting, and Participants: The cross-sectional, multicenter Alzheimer's Biomarker Consortium-Down Syndrome study included adul

Health locus of control and all-cause, cardiovascular, cancer and other cause mortality : A population-based prospective cohort study in southern Sweden

The aim was to investigate associations between health locus of control (HLC) and all-cause, cardiovascular (CVD), cancer and other cause mortality. A public health postal questionnaire was distributed in the autumn of 2008 to a stratified random sample of the 18–80 year old adult population in Scania in southernmost Sweden. The participation rate was 54.1%, and 25,517 participants were included i

Extreme variation in recombination rate and genetic diversity along the Sylvioidea neo-sex chromosome

Recombination strongly impacts sequence evolution by affecting the extent of linkage and the efficiency of selection. Here, we study recombination over the Z chromosome in great reed warblers (Acrocephalus arundinaceus) using pedigree-based linkage mapping. This species has extended Z and W chromosomes (“neo-sex chromosomes”) formed by a fusion between a part of chromosome 4A and the ancestral sex

HIV self-testing for men who have sex with men in Sweden. A cross-sectional study concerning interest to use HIV self-tests

Background: HIV self-testing (HIVST) has been found to have high acceptability among men who have sex with men (MSM) internationally and might contribute to increase testing frequencies, but many countries, including Sweden, lack policies for using HIVST. Objective: To examine interest to use and willingness to pay for HIVST, and associated factors, among MSM attending HIV testing venues in Sweden

Performance improvement of proton exchange membrane fuel cells with wavy flow channels : An experimental study

The gas flow field design plays a vital role in the cell performance of proton exchange membrane fuel cells, especially at high current densities. In this study, wavy flow channels are designed and adopted on the cathode side to enhance the mass transport process. Results demonstrate that the wavy flow channels proposed in this paper significantly improve cell performance at high current densities

Fluid flow and heat transfer in a rectangular ribbed channel with a hierarchical design for turbine blade internal cooling

For internal cooling of a turbine blade, various advanced rib turbulators can markedly contribute to the heat transfer enhancement while suffering a great increase in pressure loss. In those designs, ribs with the same configuration are periodically and evenly mounted on the channel wall. In this context, this work proposes a hierarchical design concept to optimize the rib arrangement with the des

PERSON-CENTREDNESS IN HYPERTENSION MANAGEMENT USING INFORMATION TECHNOLOGY (PERHIT) : A RANDOMISED CONTROLLED TRIAL IN PRIMARY HEALTH CARE

OBJECTIVE: Few studies address results from use of new technology and patient participation in hypertension management. The PERHIT Study is a multicentre randomised controlled trial with the aim to evaluate the effects of a person-centred approach using a web-based, interactive self-management system through the patient´s own mobile phone on blood-pressure and well-being. Primary aim is the degree

Graphene: Applications in Surface Science Studies

This thesis addresses how graphene can be a valuable asset for surface science studies. Using a combination of X- ray photoelectron spectroscopy, scanning tunneling microscopy, and low-energy electron diffraction, we take advantage of graphene’s sensitivity to changes in its chemical environment to obtain an atomic scale understanding of different reactions occurring above and below the film.As a

Outcomes and interventions in patients transported to hospital with ongoing CPR after out-of-hospital cardiac arrest - An observational study

INTRODUCTION: The main objective was to present characteristics and outcome of patients without sustained field return of spontaneous circulation (ROSC) transported to hospital with ongoing cardiopulmonary resuscitation (CPR). Our secondary objectives were to investigate hospital-based interventions and the performance of the universal Termination of Resuscitation-rule (uTOR).METHODS: In this retr