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Introduction: Mono(ADP-ribosyl)ation (MARylation) is a post tranlational modification with important roles in stress responses and cellular signaling. Mass spectrometry is an efficient tool for identifying modified amino acid residues, optimisation of parameters is desired to develop an efficient method for detection of MARylation on proteins using the recombinant protein NUDT16. Background: MAR
The number and complexity of modern software systems have increased substantially since their inception. This unrelenting growth is making manual code review more difficult year by year, and the gap between the amount of code and security verification creates a critical need for automated tools that can assist developers in detecting vulnerabilities. A possible solution to this is large language m
The task of matching fixed-order event generation with the parton shower is physically non-trivial and closely related to an efficiency bottleneck of event generators. In this thesis, we examine and implement two novel matching schemes in KrkNLO and MAcNLOPS for the LHC process p p > Z Z. As both schemes generate positive-definite event samples, they can be interesting alternatives to MC@NLO. The
What happens when the infrastructure designed to connect a city ends up dividing it instead? This thesis investigates the relationship between urban mobility and spatial justice, examining how roads, railways, and transit corridors generate barriers that are not only physical but social and cultural: separating communities, limiting access to opportunity, and reinforcing patterns of inequality ins
Dry powder inhalers (DPIs) are widely used to treat respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). The performance of DPI formulations is influenced by the properties of the active pharmaceutical ingredient (API), but systematic comparative studies of different APIs under the same processing conditions remain limited. This study investigated the effects of di
Micro- and nanoscale pollutants dispersed at low concentrations in the environment pose increasing threats to human health and ecosystems. However, investigating the properties of individual particles remains challenging because conventional characterization methods mainly rely on ensemble measurements. Optical tweezers provide a promising approach for single-particle trapping and open new possibi
In recent years, as 6G wireless systems continue to develop, high-accuracy indoor localization has become increasingly important for future wireless systems. At the same time, reliable indoor positioning is needed by many location-aware applications, such as robotic navigation, emergency healthcare, and smart transportation. Since indoor wireless measurements can vary over time due to multipath pr
HTTP-klienter används för att hämta data från servrar över ett nätverk. Det existerar flera olika användningsscenarier för dessa klienter. Detta examensarbete fokuserar på och undersöker användningen av tre olika HTTP-klienter i ett Spring Boot-system ur ett implementerings- och prestandaperspektiv. Systemet som användes var en mock-up skapad av IKEA för att efterlikna deras faktiska produktionssyHTTP clients are used to gather data from servers over a network. Several different usage scenarios for HTTP clients exist. This thesis focused on and investigated the usage of three different HTTP clients in a Spring Boot system from the perspective of implementation and performance. This system was a mock-up made by IKEA to mimic their real live Spring Boot system. The research focused on compar
Wind damage is one of the most economically and ecologically significant natural disturbances in European forests, yet the cloud cover that follows major storms routinely blocks optical satellite acquisitions for weeks, precisely when rapid damage mapping is most valuable. Synthetic aperture radar (SAR) circumvents this limitation through all-weather imaging, but pixel-level windthrow detection fr
Innovation concentrations are increasingly extending beyond metropolitan cores into urban peripheries through science parks, research infrastructures, advanced manufacturing sites, and innovation districts. Yet their physical presence does not necessarily generate long-term local development capacity. Existing research has explained innovation stability largely through agglomeration, proximity, in
Long-term university–industry strategic partnerships require continuous coordination across multiple activities, focus areas, roles, and governance levels. Using the Tetra Pak–Lund University (TP–LU) partnership as the empirical setting, this thesis aims to design a strategic partnership dashboard for governance support and to develop design-oriented knowledge for shared dashboard use in similar l
Patient-specific fluid-structure interaction (FSI) simulations can improve the understanding of mitral valve dysfunction and support preoperative planning. However, existing contracting left ventricular (LV) FSI models are often computationally demanding which limits their clinical applicability. This thesis addresses these limitations by developing a patient-specific contracting LV model within a
Traditional football analytics largely evaluates players through on-ball events such as shots, passes and dribbles, leaving the much longer periods of off-ball play poorly measured. This thesis develops a spatial framework for evaluating individual player contributions in crossing situations, where a cross is defined as an aerial or driven delivery from a wide area into the central penalty zone. T
Damaged or partially damaged pumps can cause issues that at best is an inconvenience and at worst a catastrophe. In order to prevent such issues it is necessary to catch any potential damage as early as possible. One possible solution is to use a sensor that can be placed on or near a pump in order to monitor it using audio. Audio based fault detection is still a relatively new field of research,
Preterm infants benefit from combined supplementation of arachidonic acid (ARA), docosahex-aenoic acid (DHA) and choline, but ARA/DHA-rich oils are highly susceptible to lipid oxida-tion. This project aimed to develop and evaluate choline-enriched DHA/ARA oil-in-water emulsions with suitable physical and oxidative stability. Emulsions were prepared by high-pressure homogenization using two AquaCel
Therapeutic peptides are a fast-increasing segment in the pharmaceutical industry, and GLP-1 analogues stood for two out of the three most sold drugs last year, 2025. The most common production method of peptides is based on Merrifield’s discovery of solid-phase peptide synthesis (SPPS), which uses large volumes of hazardous chemicals like N,N-dimethylformamide (DMF), piperidine, and trifluoraceti
Denna studie undersöker hur rollen som kommunal beredskapssamordnare konceptualiseras i kommunala rekryteringsannonser. Genom en kvalitativ innehållsanalys av 30 annonser analyseras vilka kunskaper, kompetenser och arbetsuppgifter som tillskrivs rollen. Resultatet visar att beredskapssamordnaren framställs som en hybridroll där specialistkunskap inom civil beredskap kombineras med generella kompet
Brädspel blir alltmer populära, vilket gör det ännu viktigare att deras regelböcker går att läsa och förstå. Denna uppsats syftar till att analysera språkbruket i strategiska brädspel i förhållande till klarspråk och forskning om instruerande text, men också att undersöka spelarnas uppfattning om spelens regelböcker. Metoden för undersökningen består av en textanalys av spelen Terraforming Mars, R
Today, digital pre-distortion (DPD) is the predominant technique for linearising the power amplifiers (PAs) used in telecommunication radio transmitters. However, conventional DPD implementations rely on power-hungry digital signal processing, making energy efficiency a critical concern. Compute in-memory (CiM) architectures have previously been demonstrated to provide significant efficiency gains
This thesis explores how large manufacturing companies in the Benelux region make sense of climate resilience and what they perceive as its key elements. Although ‘corporate climate resilience’ has gained increasing attention in academic and practitioner-oriented literature, the concept is characterised by ambiguity and fragmentation, resulting in inconsistent corporate interpretations and practic
