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Extending the dynamic range and endurance of ferroelectric tunnel junctions by conductance growth control

We use a closed-loop algorithm to accurately program hafnium zirconium oxide (HZO) ferroelectric tunnel junctions (FTJs) to arbitrary chosen target conductance values. The key enabler is suppression of conductance growth. We have identified two different mechanisms contributing to the total conductance of FTJs. By controlling both, we demonstrated an up to threefold increase of the usable conducta

Classification of 5-bit Binary Light Pulse Sequences Using Photoluminescence of Metal Halide Perovskite Memlumors

A memlumor is an innovative neuromorphic luminescent device with a state-dependent photoluminescence quantum yield (PLQY) designed for optical neuromorphic computing applications. Metal halide perovskite memlumors leverage charge trapping and photodoping to modulate the PLQY, making it dependent on the excitation light history. Here, we demonstrate the ability of perovskite memlumors to classify t

Ligand-Engineered All-In-One Cu(I) Iodide Complex Enables Near-Unity Photoluminescence and Advanced 3D X-ray Image Reconstruction

High-performance X-ray detectors are essential for 3D X-ray imaging in computed tomography (CT), but conventional systems require high radiation doses to achieve fine resolution. All-In-One (AIO) Cu(I) halide complexes, capable of forming both ionic and coordinate bonds within a single structure, offer efficient scintillation at lower doses, yet their performance remains limited by nonradiative en

Multi-Level Analog Computing-In-Memory FeFET-based Unit Cell for Deep Learning

This paper shows a FeFET-based analog multi-level unit cell for computing-in-memory applications for Deep Neural Networks (DNN). The FeFET-based unit cell performs input-weight multiplication with a Back-End-Of-Line (BEOL) ferro-electric HZO FeFET device on top of standard 180 nm CMOS circuits. The unit cell works with a feedback mechanism which combines an in-house FeFET device to store weights a

Cryo-optical setup for wide-field microscopy and spectroscopy of luminescent nanomaterials

Studying photoluminescence (PL) is essential for understanding and engineering light-emitting nanomaterials. Heterogeneous samples, such as thin films and microstructures, require characterization of the spatial distribution of PL intensity, spectra, lifetimes, and photon correlations at the microscale under variable temperatures. Here we describe a cryo-optical setup for micro-PL imaging, spec

ACS Nano Journal Cover

Depiction of sinusoidal displacement in nanocrystal superlattices through a minimum of geometric shapes and contrasting colors. This cover pays homage to the Bauhaus movement, celebrating human-made craftsmanship, clarity, and accessibility in scientific design, and remains faithful to its fundamental principle: less is more.

“Oxygen tone” drives stage-specific OPC phenotypes for cell-based stroke therapy

Oligodendrocyte precursor cells (OPCs) display functional plasticity beyond myelination. Kuwata et al. explore how hypoxia shapes OPC features after ischemic stroke. Combining single-cell transcriptomics with in vivo and ex vivo models, they reveal oxygen-dependent OPC phenotypes promoting angiogenesis and remyelination, highlighting OPC versatility and potential for novel stroke cell therapies.

Aducanumab binding to Aβ1-42 fibrils alters dynamics of the N-terminal tail while preserving the fibril core

Aducanumab, a human IgG1 antibody with plaque-clearing effects and modest clinical benefit, binds selectively to aggregated Aβ via the N-terminal region. Yet, the molecular details of how the antibody engages Aβ1-42 fibrils remain unresolved. Using magic-angle spinning NMR, we show that binding of aducanumab preserves the overall architecture of the Aβ1-42 fibril core while inducing significant st

Long-term exposure to black carbon and incident asthma and chronic obstructive pulmonary disease in adults : The Danish Nurse Cohort

Background: Air pollution is a known risk factor for chronic respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). However, evidence regarding the role of black carbon (BC) remains mixed and sparse. This study aimed to examine the association of long-term exposure to air pollution, focusing on BC, with incident asthma and COPD in adults. Method: We followed 28,73

Highly-destabilized ligand field excited states of iron carbene complexes and their relation to charge transfer state lifetimes

Lifetimes of photoexcited charge transfer (CT) states in transition metal chromophores are influenced by low-lying ligand field (LF) excited states, especially for 3d metal complexes. To manipulate interactions between LF and CT states, it is important to be able to control LF excited state energies using tunable synthetic variables. In this report, we use Fe 2p3d L3-edge resonant inelastic X-ray

Multiexciton absorption cross sections of CdSe@CdS nanorods studied using pump–repump–probe spectroscopy

While the multiexciton dynamics in semiconductor nanocrystals is widely explored, to determine the absorption cross sections for multiexcitons of varying order is still a challenge. In this study, we performed pump–repump–probe transient absorption (ppp-TA) spectroscopic measurements on CdSe@CdS nanorods to gain insights into the absorption cross sections for multiexcitons. By tuning the pump–repu

Self- and co-assembly of the amyloid suppressing chaperone DNAJB6b

The clustering of certain proteins into oligomers and fibrils, known as amyloids, underlies the pathology of diseases such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. These processes are counteracted by the cellular protein quality control system, which includes molecular chaperones that interact with disease-associated proteins. One such chaperone is DNAJB6b, which has gaine

How Antisolvent-Induced Ligand Stripping Shapes CsPbX3 Nanocrystals and Their Assemblies

Supercrystals of lead-halide perovskite nanocrystals combine the semiconducting properties of bulk perovskites with quantum confinement effects and extend them to the macroscopic scale. Supercrystals assembled via a two-layer phase diffusion process using an acetonitrile antisolvent were recently shown to be unusually robust. We investigate how the acetonitrile-assisted self-assembly process influ

An unusual case of Streptococcus pyogenes infective endocarditis demonstrating the usefulness of repeated echocardiography

Infective endocarditis (IE) is most often caused by alpha-hemolytic streptococci or Staphylococcus aureus and is characterized by the presence of vegetations on the heart valves. Here we present a case of IE caused by Streptococcus pyogenes, a distinctly uncommon IE-pathogen, where no vegetations could be visualized on repeated echocardiography. Diagnosis was instead evident from septic embolizati

Economic evaluation of diabetes prevention interventions in Bangladesh : A modelling study

Aim: To model the long-term cost-effectiveness of scaling up two prevention interventions against type 2 diabetes mellitus (T2DM), i.e. community mobilisation through participatory learning and action (PLA) and mHealth mobile phone messaging, implemented in rural Bangladesh as part of the “DMagic” trial. Methods: A health-economic Markov model of the three-arm, cluster-randomised controlled DMagic

National implementation of vaginal Natural Orifice Transluminal Endoscopic Surgery for benign hysterectomies : A historical cohort study of Swedish data 2021–2023

Introduction: Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a technique combining vaginal entrance to the abdomen with endoscopic overview. Previous studies have shown that vNOTES decreases operating time, hospitalization, postoperative complications, and pain. We aimed to present patient demographics, costs, and surgical outcomes following the implementation of vNOTES for be