Single-shot spatio-temporal characterization of petawatt laser pulses
A spectrally and polarization-resolved wavefront detector can measure the spatio-temporal vector electric field of ultrashort laser pulses in a single shot.
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A spectrally and polarization-resolved wavefront detector can measure the spatio-temporal vector electric field of ultrashort laser pulses in a single shot.
The expansion of the electric vehicle industry is driving increased demand for lithium-ion batteries (LIBs), which in turn creates challenges in material availability and waste management that more durable LIBs could address. Electrode surface coating helps extend LIB lifespan, with atomic layered deposition (ALD) as the preferred method due to its precise thickness control and ability to coat var
The growing complexity of urban energy systems, climate uncertainties, and geopolitical disruptions highlight the need for energy flexibility and smart management. Recent developments in smart buildings enable real-time adaptability and collective energy behavior through the deployment of Reinforcement Learning (RL), which optimizes energy use, integrates distributed resources, and enhances demand
The dispersion-scan technique (d-scan) is a well-established technique for the measurement of ultrashort laser pulses. While a single-shot version of d-scan is relatively easy to implement for sub-10 fs laser pulses, this becomes increasingly difficult as the pulse duration increases due to the need for a larger dispersion range, which scales quadratically with the Fourier transform limit (FTL). H
Insulin resistance (IR) contributes to atherogenic dyslipidemia and elevated ASCVD risk. Apolipoprotein A1 (ApoA1)-associated lipoproteins have diverse anti-atherogenic functions, but it is unclear whether IR drives adverse changes in their proteomic composition. We hypothesized that IR is associated with an atherogenic ApoA1 proteome and that insulin-sensitizing interventions would improve its co
Photonic topological insulators and self-induced nonreciprocity based on nonlinear effects in asymmetric structures have garnered increased attention due to their potential applications in quantum information technologies and advanced photonic integrated circuits. In this study, we combine these two fields and present asymmetric photonic crystal designs based on all-dielectric checkerboard structu
BACKGROUND: Digital technologies are increasingly central to supporting autonomy, health, and social participation in later life. However, disparities persist in the ability to keep up with technological developments, affecting individuals' opportunities to benefit from digital health and social innovations.OBJECTIVE: This study aimed to investigate factors associated with individuals' self-report
Objective Delivery of a small for gestational age (SGA) infant is a common pregnancy complication among women with SLE. Although disease activity and autoantibodies such as anti-Smith and anti-ribonucleoprotein associate with SGA, underlying pathological mechanisms remain unclear and reliable predictors are lacking. To address this, we applied a proteomic approach to identify proteins associated w
This work introduces a sustainable and versatile synthesis platform for nanosized metal–ceria catalysts with tunable composition, directly relevant to renewable energy conversion and CO2 utilization. The method enables parallel preparation of multiple catalysts in a single batch with high yield and reproducibility, while reducing environmental impact by 92% compared to conventional approaches, as
Background Preserved ratio impaired spirometry (PRISm) and restrictive spirometry pattern (RSP) are associated with increased morbidity and mortality, but the underlying mechanisms are unclear. Impulse oscillometry (IOS) measures small airway function more sensitively than spirometry. We aim to study the prevalence of abnormal IOS findings in relation to three spirometry patterns (obstructive, PRI
BACKGROUND: Cardiovascular calcification is a significant predictor and contributor to cardiovascular diseases. Vascular smooth muscle cell (SMC)-derived extracellular vesicles (EVs) play a crucial role in microcalcification formation. EVs can originate from the endosomal system, and PIKFYVE (1-phosphatidylinositol 3-phosphate 5-kinase), a lipid kinase, plays a key role in endomembrane maturation.
Carbon Black (CB), graphene, and nanodiamonds represent three classes of manufactured carbonaceous nanoparticles consisting almost exclusively of insoluble material. Particle-related Reactive Oxygen Species (ROS) have been linked to in vivo and in vitro toxicity and determining particle ROS activity is an efficient way of estimating nanomaterial toxicity and assist in the safe-by-design developmen
IntroductionSport-related concussion (SRC) is a pressing issue in Para sport, yet biomechanical mechanisms remain poorly understood. Athletes with visual impairment face elevated risks due to sport-specific demands, such as frequent collisions in blind football. This pilot study examined head acceleration responses in blind football players compared with non-disabled football players, and between
Introduction: It is well known that urinary tract infection (UTI) during pregnancy is associated with preterm birth, but information about the risk of preterm birth depending on gestational week of infection is sparingly described in the literature. Material and Methods: An observational study based on data from Swedish registers including women giving birth 2014–2020 (n = 684 595). Pregnant women
Objective: To describe longitudinal changes of Magnetic Resonance Imaging (MRI) features in the medial vs lateral tibiofemoral (TF) and patellofemoral (PF) compartments, in knees with no radiographic osteoarthritis (OA) at baseline. Design: In 340 individuals from the Osteoarthritis Initiative aged 45–55 years (51% women) with 430 knees at risk for OA and 250 not at risk, we assessed MRI scans of
Background: Pro-neurotensin (pro-NT) is the stable circulating precursor of neurotensin (NT), a neuropeptide expressed mainly in the central nervous system and small intestine that regulates key physiological processes like fatty acid absorption in the gut and suppresses appetite via central mechanisms. Studies in NT-deficient mice and humans implicate NT in obesity and insulin resistance, highlig
Hyperbolic phonon polaritons - hybridized modes arising from the ultrastrong coupling of infrared light to strongly anisotropic lattice vibrations in uniaxial or biaxial polar crystals - enable to confine light to the nanoscale with low losses and high directionality. In even lower symmetry materials, such as monoclinic (Formula presented.) -Ga2O3 (bGO), hyperbolic shear polaritons (HShPs) further
Background: Metformin is one of the most used drugs worldwide. Given the increasing use of proteomics in trials, bioresources, and clinics, it is crucial to understand the influence of metformin on the levels of the circulating proteome. Methods: We analysed a combined longitudinal proteomics dataset from the IMPOCT, RAMP and S3WP-T2D clinical trials in 98 participants before and after metformin e