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The TACSI trial (ClinicalTrials.gov Identifier: NCT03560310) tests the hypothesis that 1-year treatment with dual antiplatelet therapy with acetylsalicylic acid (ASA) and ticagrelor is superior to only ASA after isolated coronary artery bypass grafting (CABG) in patients with acute coronary syndrome. The TACSI trial is an investor-initiated pragmatic, prospective, multinational, multicenter, open-
OBJECTIVES: Occupational exposure to vibration using hand-held tools may cause hand-arm vibration syndrome (HAVS). Correct diagnosis and grading of severity are crucial in protecting the individual's health and for workers' compensation claims. The International Consensus Criteria (ICC) has been suggested to replace the widely used Stockholm Workshop Scale (SWS). The aims were to, in a clinical se
Searches for the exclusive decays of Higgs and Z bosons into a vector quarkonium state and a photon are performed in the μ+μ-γ final state with a proton–proton collision data sample corresponding to an integrated luminosity of 139 fb - 1 collected at s=13 TeV with the ATLAS detector at the CERN Large Hadron Collider. The observed data are compatible with the expected backgrounds. The 95% confidenc
PURPOSE: To investigate estimated delivered dose distributions using weekly cone-beam computed tomography (CBCT) scans for pelvic organs at risk (OARs) in salvage radiotherapy (SRT) after radical prostatectomy. Furthermore, to compare them with the originally planned dose distributions and analyse associations with gastrointestinal (GI) and genitourinary (GU) side effects.METHODS: This study is pa
A search for physics beyond the Standard Model inducing periodic signals in the dielectron and diphoton invariant mass spectra is presented using 139 fb−1 of s = 13 TeV pp collision data collected by the ATLAS experiment at the LHC. Novel search techniques based on continuous wavelet transforms are used to infer the frequency of periodic signals from the invariant mass spectra and neural network c
BACKGROUND: After breast-conserving surgery, radiotherapy reduces recurrence and breast cancer death, but it may do so more for some groups of women than for others. We describe the absolute magnitude of these reductions according to various prognostic and other patient characteristics, and relate the absolute reduction in 15-year risk of breast cancer death to the absolute reduction in 10-year re
Quantum annealing has shown promise for finding solutions to difficult optimization problems, including protein folding. Recently, we used the D-Wave Advantage quantum annealer to explore the folding problem in a coarse-grained lattice model, the HP model, in which amino acids are classified into two broad groups: hydrophobic (H) and polar (P). Using a set of 22 HP sequences with up to 64 amino ac
Aim: To provide a comprehensive description of the clinical features, biochemical characteristics, and outcomes of infants up to 90 days old with COVID-19. Moreover, to assess the severity of the disease and propose an effective management pathway. Methods: Retrospective single-center study spanning three years. Patient data includes age, sex, symptoms, comorbidities, blood and urine test results,
Myanmar is the world's second-largest producer of opium poppy, the raw material from which heroin and opium are produced. 85% of this opium poppy is cultivated in rural areas of Shan State, where about 1 in 10 households in the villages are directly involved in opium poppy cultivation for the drug industry (MIMU, 2017). The economy of opium poppy permeates social and family dynamics; nonethele
In the coming decades, the twin energy and digital transitions will require the rapid scaling and deployment of renewable energy technologies and advanced technologies within ‘critical raw materials’ (CRMs) are essential components. At the same time, as CRM reserves are heterogeneously distributed, concentrated in a few countries with refining in even fewer still, demand is expected to outstrip su
Mitigation of greenhouse gas (GHG) emissions is essential for us humans to curb climate change. Around a fifth of the anthropogenic GHG emissions stem from the construction sector. Much come from energy used for space and water heating within buildings, but an increasing proportion comes from the manufacturing of the building materials and is virtually embodied within buildings. This is called Emb
This thesis has two major purposes: (1) to create a 3D virtual “reconstructive” model of the peristyle with the nymphaeum wall (room b) of the house V 1,7 (House of the Bronze Bull) in Pompeii, and (2) to prepare a probability map based on this model that will show the reliability level for each individual part. The author underlines the importance of recording paradata of the entire workflow. The
The presumption of parental liability is an important tool for the Commission, enabling it to hold parent companies jointly and severally liable with their subsidiaries. Parent companies claim however, that they cannot rebut the presumption and are thus rendered strictly liable for their subsidiaries’ conduct. Due to the fact that parent companies repeatedly failed rebutting the presumption with e
Lesbian, gay, and bisexual people continue to face discrimination and persecution in their daily lives, often from both the state and their communities. Where states do not provide for the basic human rights and physical security of their lesbian, gay, and bisexual citizens, many such citizens would flee their countries of origin in search of refuge in more hospitable countries. If other countries
Background. Flattening filter-free (FFF) beams are an emerging technology that has not yet been widely implemented as standard practice in radiotherapy centers. To facilitate the clinical implementation of FFF, we attempted to elucidate the difference in plan quality and treatment delivery time compared to flattening filter beams (i.e. standard, STD) for several patient groups. We hypothesize that
