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This thesis reports a study involving the use of Halomonas boliviensis, a moderate halophile, for production of biopolyester poly(3-hydroxybutyrate) (PHB) and compatible solutes ectoine and hydroxyectoine through high cell-density cultivation comprising fed-batch cultures. PHB is a biodegradable plastic produced by bacteria as energy reserve and can potentially be used as a replacement of fossil b
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Popular Abstract in Swedish Trycksatt fluidiserande bädd förgasning är ett effektivt sätt för att omvandla biomassa till en gas som kan användas i olika tillämpningar: som bränsle till gasturbiner och förbränningsmotorer, som råvara till kemikalieproduktion eller som bas i tillverkning av syntetiska drivmedel. I motsatts till rötning och jäsning lämnar termisk förgasning inga kontaminerade restproFluidised bed thermal gasification of biomass is an effective route that results in 100 % conversion of the fuel. In contrast to chemical, enzymatic or anaerobic methods of biomass treatment, the thermal conversion leaves no contaminated residue after the process. The product gas evolved within thermal conversion can be used in several applications such as: fuel for gas turbines, combustion engine
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Popular Abstract in Swedish Denna avhandling handlar om en ärftlig hjärnsjukdom som heter Huntingtons sjukdom, eller danssjuka. Sjukdomen leder till personlighetsförändringar, ofrivilliga rörelser (som ser ut som om personen dansar) och demens. Personer som drabbas dör 15-20 år efter att symptomen har brutit ut, och en god behandling eller botemedel saknas. Sjukdomen orsakas av att HuntingtongenenHuntington's disease (HD) is a hereditary neurodegenerative disorder caused by an expansion of a CAG repeat in the HD gene, that leads to dysfunction and death of striatal neurons. The pathogenetic mechanisms underlying HD are not known, but excitotoxicity and dopamine (DA) have been suggested to play a role. In this thesis, the effects of excitotoxicity and DA have been studied in striatal in vit
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Popular Abstract in Swedish Värdebaserad styrning har på senare tid tilldragit sig mycket intresse från såväl akademiker som praktiker. På basis av fallstudiemetod beskrivs, analyseras och konceptualiseras värde¬bas¬erad styrning utifrån ett ekonomistyrningsperspektiv. Medan tidigare forskning har fokuserat på de presstationsmått som lanseras i den normativa litteraturen visar denna avhandling atValue-based management has attracted considerable interest among organizations and academics in recent years. Responding to calls for case-based research, this thesis describes, analyses and conceptualizes value-based management as a management accounting construct. While previous research has focused on the measures (eg. EVA) advanced in the normative literature, this analysis demonstrates that
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This thesis provides the first attempt to study the nicotinamides and benzamides from a mode of action point of veiw. Understanding the effects on DNA repair, cell cycle control (proliferation) and cell death from these agents and in combination with ionizing radiation, provides a new opportunity to logically develop better approaches to sensitize already existing therapies via for example inducti
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Methacrylate-functionalized poly(ethylene oxide-co-ethylene carbonate) macromonomers were prepared in two steps by the anionic ring-opening polymerization of ethylene carbonate at 180 °C, with potassium methoxide as the initiator, followed by the reaction of the terminal hydroxyl groups of the polymers with methacryloyl chloride. The molecular weight of the polymer went through a maximum after app
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With the introduction of mammographic screening the incidence of ductal carcinoma in situ (DCIS) has increased to 10-15% of all breast cancers. The aim of this study was to investigate whether there were any morphological and cell biological differences between DCIS detected during the pre-screening (n = 39) as opposed to the screening period (n = 120). We could not demonstrate any statistically s
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This article examines the genetic relationships among 34 MSS suspected of being related because of a peculiar shared reading in John 8:8b-9a: "he wrote on the ground the sins of each..." A quantitative analysis detected several independent families, including new family P members and a dozen MSS forming "family Patmos/M;" this family, in turn, includes the original Patmos family discovered by Silv
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A new approach to the design of time windows is presented for detection of transient-evoked otoacoustic emissions (TEOAE). The windows are designed with reference to a minimum mean square error criterion involving the correlation properties of the ensemble of responses. Latency information is introduced in the detection process by windowing at different scales that result from wavelet decompositio
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We present the red-listed plants and fungi that have been found in the central parts of the parish of Stenbrohult, southern Sweden. In the middle of the study areas Carl Linnaeus was born in 1707, and he spent his summers there until 1727. Of the 11 currently red-listed vascular plants (Gärdenfors 2000) that have been recorded since 1970 all occurred there also 300 years ago. Mosses, lichens and f
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Serum and urinary concentrations of NCl, the non collagenous globular domain of collagen IV, were used as markers for turnover of basement membranes. NCl levels were studied in membranous glomerulonephritis and diabetic nephropathy. Thirteen patients with membranous glomerulonephritis and 8 insulin-dependent diabetic patients with diabetic nephropathy were compared to 16 apparently healthy control
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Effects of topology, length, and charge on peptide interactions with lipid bilayers was investigated for variants of the human kininogen-derived peptide HKH20 (HKHGHGHGKHKNKGKKNGKH) by ellipsometry, CD, fluorescence spectroscopy, and z-potential measurements. The peptides display primarily random coil conformation in buffer and at lipid bilayers, and their lipid interaction is dominated by electro
