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The invention relates to hyperpolarised 13C-α-ketoisocaproate, its use as imaging agent, an imaging medium comprising hyperpolarised 13C-α-ketoisocaproate and methods of 13C-MR detection wherein such an imaging medium is used. Further, the invention relates to methods of producing hyperpolarised 13C-α-ketoisocaproate.

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An extensive follow-up study of day- and night-active Macrolepidoptera was performed during 2004 at the Kullaberg Nature Reserve located in the south-western part of Sweden. Butterflies were surveyed in an area of 100 km(2) and night-active moths were trapped in the core area of the reserve. Macrolepidopteran species resident in the area in the 1950s were compared with species resident in the area

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Mild heat treatment of carrot slices as a pre-treatment for frozen storage was accomplished by exposure of slices to radiant heat to maximise thermal exposure of the cells at the surface while preserving the integrity of cells within the slices. Cell damage as a consequence of this treatment on texture was evaluated. Carrot slices treated for 7 s with radiant energy in the far-infrared region from

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Head and neck squamous cell carcinomas (HNSCC) are often characterized by complex karyotypic changes, and a substantial proportion of the reported tumors have shown intratumor heterogeneity in the form of cytogenetically related (40%) or unrelated clones (20%). In order to study intratumor heterogeneity and to distinguish the temporal order of chromosome rearrangements in these tumors, two or more

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The aim of this work was to explore the possibility of mixed feedstocks utilization using acid-catalyzed steam pretreatment in the context of forest biomass. Three steam pretreatment conditions were applied to characterize the interactions between spruce (softwood) and poplar (hardwood) that were concurrently processed by SO2-catalyzed steam pretreatment and enzymatic hydrolysis. The effects of bl

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While COVID-19 is a global pandemic, different countries have experienced different morbidity and mortality patterns. We employ retrospective and prospective space–time permutation analysis on COVID-19 positive records across different municipalities in Sweden from March 2020 to February 2021, using data provided by the Swedish Public Health Agency. To the best of our knowledge, this is the first

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The relative importance of exploitation rate and environmental variability in generating fluctuations of harvested populations is a key issue in academic ecology as well as population management. We studied how the eastern Baltic cod (Gadus morhua) is affected by fishing and environmental variation by using a newly developed single species state-space model. Survey data and auxiliary environmental

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Objectives: To assess level of degeneration in human knee cartilage and meniscus in donors without clinically-evident knee arthritis, in relation to age and sex. Further, to investigate the association between cartilage and meniscus degeneration. Design: Histological sections of knee cartilage and meniscus from 44 deceased donors (ages 18–85 years) without clinically-evident osteoarthritis or infl

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Drylands account for a disproportionate share of the world’s armed conflicts, a pattern frequently interpreted through the lens of resource scarcity– where climate change and water stress are seen as primary drivers of violence. While this framing underscores critical environmental pressures, it risks simplifying the complex social, ecological and political realities of these regions. This article

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This paper identifies a challenging situation in the architectural education. It discusses the case of mixing two levels of students, working in a group albeit with the same assignment in one studio. Precisely, having the first and the second year students of Architecture in one design studio at Lund University/ Sweden. The paper examines this situation from four different didactic perspectives, s

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This perspective article explores how sustainability transitions experience a geo-economization based on rising concerns about sovereignty. We argue that sovereignty has yet again become an active force structuring socio-technical trajectories. In this case, socio-technical systems tend to be reconfigured in ways that first and foremost ensure the continued provision of their core societal functio

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The potential to source thermal energy from buried infrastructure such as tunnels and metro stations may offer significant potential to reduce the carbon dioxide emissions of heating and cooling, and reduce the costs associated with dedicated drilling for traditional ground-sourced systems. However, this remains a niche approach with few commercial schemes globally, partly due to high initial cost

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Introduction: Evidence for gut–kidney interactions in early kidney disease is limited, particularly in community-dwelling adults with largely preserved kidney function. Here, we quantified links between gut microbiota and estimated glomerular filtration rate (eGFR) in two population-based Swedish cohorts. Methods: Deep shotgun metagenomics profiled fecal samples from 9788 adults in the Swedish CAr

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This meta-analysis and systematic review examined the effects of psychedelic substances on death anxiety, specifically evaluating whether psychedelic experiences are associated with statistically significant reductions in death anxiety. A systematic search identified 8 studies suitable for meta-analysis and 10 additional studies for systematic review. Using a random-effects model, the meta-analysi

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Quantum information and quantum computing are based on the concept and manipulation of qubits. In this pedagogical Tutorial-written with the aim of assisting self-motivated undergraduate mathematics, physics, and engineering students-transformation of these qubits, especially the Hadamard transformation (H) and the phase shifter transformation (φ), is illustrated. Two-qubit gates and their applica

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Quantification using the Centiloid (CL) scale has become a valuable information to consider when interpreting amyloid-PET images and is now implemented in several software packages. This work aims to assess the comparability of CL from [18F]flutemetamol scans derived using several research and commercial quantification pipelines. Methods: This analysis relies on three datasets: a test-retest cohor

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Cyanobacteria are bioactive compounds that produce toxins known as harmful algal blooms, posing serious threats to humans and marine life. Consequently, developing a robust monitoring framework to track and forecast the growth of such blooms is critical. The present work aims to understand the key environmental drivers influencing cyanobacterial bloom dynamics along the Southeast coast of India us