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Studying gene-lifestyle interaction may help to identify lifestyle factors that modify genetic susceptibility and uncover genetic loci exerting important subgroup effects. Adequately powered studies with prospective, unbiased, standardised assessment of key behavioural factors for gene-lifestyle studies are lacking. This case-cohort study aims to investigate how genetic and potentially modifiable

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Objective To standardize the evaluation of regional fetal brain blood perfusion, using power Doppler ultrasound (PDU) to estimate the fractional moving blood volume (FMBV) and to evaluate the reproducibility of this estimation. Methods Brain blood perfusion was evaluated in 35 normally grown fetuses at 28-30 weeks of gestation, using PDU. The following cerebral regions were included in the PDU col

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Two probiotic products containing either live Lactobacillus plantarum strain DSM 15313 or bilberries fermented by the same bacterial strain were tested for their antihypertensive potentials and their impact on the oral and the faecal microbiota in hypertensive adults. The results showed that consumption of the tested products for three months did not reduce the blood pressure in adults with hypert

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BACKGROUND: Leucocyte recruitment and inflammation are key features of high dose radiation-induced tissue injury. The inflammatory response in the gut may be more pronounced following radiotherapy due to its high bacterial load in comparison to the response in other organs. We designed a model to enable us to study the effects of radiation on leucocyte-endothelium interactions and on intestinal mi

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Purpose: This thesis aims to develop conceptual implications from interpretation of theories and case study on cross border M&As conducted by firms from emerging market with focus on the perspectives of motivation, integration and performance. Methodology: This thesis is developed through a descriptive case study on two related cases from emerging markets. Detailed implications are derived fro

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BACKGROUND: Surveys are a common way to measure annoyance due to road traffic noise, but the method has some draw-backs. Survey context, question wording and answer alternatives could affect participation and answers and could have implications when comparing studies and/or performing pooled analyses. The aim of this study was to investigate the difference in annoyance reporting due to road traffi

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This paper begins with describing a case study of using the standard Web Map Services (WMS; from Open Geospatial Consortium) for mobile applications. There are two experiences from this case study that are interesting for the generalisation community: the amount of map information on the screen and the map file size. In this paper a usability study of the amount of map information is presented. Th

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In the formulation of an active enzyme enclosed in a matrix for controlled delivery, it is a challenge to achieve a high protein load and to ensure high activity of the protein. For the first time to our knowledge, we report the use of a highly swollen lipid sponge (L3) phase for encapsulation of the large active enzyme, β-galactosidase (β-gal, 238 kDa). This enzyme has large relevance for applica

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Intrinsically disordered proteins (IDPs) adopt heterogeneous conformational ensembles in solution. The properties of the conformational ensemble are dependent upon the solution conditions, including the presence of ions, temperature, and crowding, and often directly impact biological function. Many in vitro investigations focus on the properties of IDPs under dilute conditions, rather than the cro

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Malaria is a public health problem which affects developing countries world-wide. Inadequate skilled lab technicians in remote areas of developing countries result in untimely diagnosis of malaria parasites making it hard for effective control of the disease in highly endemic areas. The development of remote systems that can provide fast, accurate and timely diagnosis is thus a necessary innovatio

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Solar energy simulations are used to quantify the potential of the passive use (daylight, solar gains) and the active use (photovoltaics and solar thermal) of solar energy. The simulations can be performed at different scales e.g. buildings, neighbourhoods and cities, with different requirements on the data. For example, for the neighbourhood simulations we need simplified building geometries that

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In this 2 hour workshop the experiences of the geographic data domain will be shared with the open data research & education community to promote and strengthen active innovative learning and teaching in both worlds. The domain of geographic data can be considered as one of the front running in open data. Over the past two decades, many geographic datasets in Europe became available as open da

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OBJECTIVE: To investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia.DESIGN: Nationwide prospective register based cohort study.SETTING: Denmark.PARTICIPANTS: 1 938 994 adults aged ≥60 years living in Denmark between 1 January 2004 and 31 December 2017.MAIN OUTCOME MEASURES: Incident cases of all cause dementia and dementi

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Various mechanisms have been proposed for hydrogen embrittlement of duplex stainless steel, but the causation of hydrogen-induced material degradation has remained unclear. This work shows that phase instability (decomposition) of the austenite phase and ductile-to-brittle transition of the ferrite phase precedes hydrogen embrittlement. In-situ diffraction measurements revealed that Ni-rich sites