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Ecology and sexual conflict drive the macroevolutionary dynamics of female-limited color polymorphisms in damselflies

Sexual conflict over mating has been documented in many species, both in the field and in experimental studies. In pond damselflies (family Coenagrionidae), sexual conflict maintains female-limited color polymorphisms, with one female morph typically being a male mimic. However, it is not known whether sexual conflict can also explain the evolutionary origin of novel female morphs, and if so, what

GP turnover in a multiprofessional team-based primary care system : evidence from Sweden

BACKGROUND: GP recruitment and retention difficulties challenge the traditional general practice model. Task-shifting and relieving GPs from financial risk have been suggested to make primary care more attractive. In Sweden's multiprofessional team-based primary care system, GPs usually work as salaried employees and there is extensive task-shifting. Salaried employment facilitates mobility, poten

Proof-of-concept for a randomized factorial design strategy to build a complex online support program for cancer survivors with psychiatric symptoms : the IN-FACT-0 feasibility trial

Purpose: Internet-delivered cognitive behavioral therapies and lifestyle interventions are promising for reducing psychiatric symptoms in cancer survivors, but little is known about the contribution of specific treatment components to observed effects. A randomized factorial trial could allow for evaluation of the unique contribution of treatment components to overall treatment effects. The IN-FAC

En oåterkalleligt undergrävd rättvisa? - En rättsdogmatisk studie av provokationsinstitutet ur ett processrättsligt perspektiv i ljuset av artikel 6 Europakonventionen

Brottsbekämpande myndigheter använder sig ibland av okonventionella utredningsmetoder för att tillmötesgå en alltmer komplex brottslighet. Ett exempel på en sådan metod är användningen av provokativa åtgärder, som innefattar hemliga utredningsåtgärder eller brottsprovokationer. Ur ett effektivitetsperspektiv är det obestridligt att tendenser i brottsutvecklingen nödvändiggör mer sofistikerade arbeLaw enforcement authorities occasionally employ unconventional investigative techniques in response to increasingly complex forms of criminality. One such technique is the use of covert and provocative measures, including undercover operations and police incitement. From one standpoint of effectiveness, it is indisputable that developments in criminal activity necessitate increasingly sophisticate

“Where and how do you buy medicines?” A pilot survey of consumption strategies among the public in Sweden

Substandard and falsified (SF) medical products are a major danger to public health. They affect every region of the world, and have been identified in all major therapeutic categories. Studies from medicine, pharmacology, law and public health dominate this research area with a focus on the supply side. However, the spread of SF medical products cannot be fully understood without information abou

Sexual Harassment in the Workplace in Relation to EC Legislation

The first part of the article is an outline of the nature of sexual harassment, its extent and the growing awareness of it. The second part considers why there was a need for a community initiative and looks at the extent of sexual harassment in the Member States, the consequences of sexual harassment, legal remedies and the impact it has on the community's principles, including health and safety

Cancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells

We present a unifying theory to explain cancer recurrence, therapeutic resistance, and lethality. The basis of this theory is the formation of simultaneously polyploid and aneuploid cancer cells, polyaneuploid cancer cells (PACCs), that avoid the toxic effects of systemic therapy by entering a state of cell cycle arrest. The theory is independent of which of the classically associated oncogenic mu

Nasal polyposis is a risk factor for nonadherence to CPAP treatment in sleep apnea : the population-based DISCOVERY study

STUDY OBJECTIVES: The aim was to evaluate nasal polyposis as a risk factor for nonadherence to continuous positive airway pressure (CPAP) treatment in patients with obstructive sleep apnea (OSA). METHODS: This was a population-based, longitudinal analysis of patients starting CPAP treatment for OSA in the Swedish quality registry Swedevox between 2010 and 2018. Data were cross-linked with national