Filtyp
Muscle contraction studies often focus solely on myofibres and the proteins known to be involved in the processes of sarcomere shortening and cross-bridge cycling, but skeletal muscle also comprises a very elaborate ancillary network of capillaries, which not only play a vital role in terms of nutrient delivery and waste product removal, but are also tethered to surrounding fibres by collagen "wir
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA Akut inflammation i bukspottskörteln (akut pankreatit, AP) är en vanlig sjukdom som oftast debuterar med kraftiga buksmärtor och ibland illamående och kräkningar. De flesta patienter, ungefär 80%, får en mild form av sjukdomen som begränsas till just bukspottkörteln (pancreas), och dessa patienter tillfrisknar efter några daAcute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. The aim of this thesis was to define the influence of platelets and neutrophils as well as their interrelations in re
The problems of allocation of scarce resources and priority setting in health care have so far not been much studied in the context of stem cell-based therapeutic applications. If and when competitive cost-effective stem cell-based therapies are available, the problem of priority setting - to whom should stem cell-based therapies be offered and on what grounds - is discussed in this article using
Development and application of some laser techniques for the study of engine combustion are presented. The investigations mainly cover two aspects: fuel dynamics and formation of NO. Fuel dynamics is one of the most central problems in engine design since many performance parameters are affected by it; emission formation, efficiency, drivability etc. The studies include cycle-resolved measurement
The basement rocks of southern Sweden were deeply weathered in Late Triassic through Cretaceous times, and possibly even earlier. Sub-Mesozoic saprolites formed, presumably due to long-term warmth and humidity, in conjunction with decomposition of abundant organic matter and subsequent infiltration of acidic water. The upper parts of the weathering profiles were subjected to intense leaching and k
During the past century, Lake Takern and Lake Krankesjon, southern Sweden, have shifted repeatedly between a state of clear water and abundant submerged vegetation, and a state of turbid water and sparse vegetation. Long-term empirical data on such apparently alternative stable state dynamics are valuable as complements to modeling and experiments, although the causal mechanisms behind shifts are
OBJECTIVE: To analyze the extent of tumor necrosis factor-alpha (TNFalpha) and TNFbeta gene polymorphism in patients with AD and to relate it to intrathecal levels of these cytokines. METHODS: Analyses of TNFalpha and TNFbeta gene polymorphism were performed using PCR in 52 patients with AD and in 25 control subjects, and the levels of corresponding cytokines were analyzed using ELISA. RESULTS: Pa
Popular Abstract in Swedish Formstabilitet, dvs. förmågan för träet att behålla sin form, är en av de viktigaste parametrarna när trä används som byggnadsmaterial eller för andra ändamål. I allmänhet ändras träets dimensioner och form när dess fuktkvot ändras. Detta är dock inte önskvärt i konstruktioner, varför det behövs metoder som förbättrar formstabiliteten. I denna avhandling har inverkan aShape stability, the ability of the wood to retain its shape, is one of the most important parameters when using timber as a building material and for other applications. Generally, timber undergoes changes in dimensions and shape when its moisture content is changed. However, this can often not be tolerated in constructions and thus, methods to improve the shape stability have to be found. In th
The aim of this study was to study the relationship between physician-assessed quality of life parameters, i.e., toxicity and physical performance, and patients' self-reports of their quality of life (QoL). QoL was assessed at baseline and before each treatment. using the EORTC QLQ-C30. The WHO performance score (PS) and toxicity were assessed in physician interviews. The correlations between the
The relationships between, on the one hand, burnout, empathy and sense of cohoerence (SOC) and, on the other, personality traits were investigated, together with the effects of systematic clinical supervision on these phenomena among Swedish district nurses. The results in the supervisory group (n = 21) were compared with those of a comparison group (n = 12) in a quasi-experimental design. Persona
PURPOSE AND MATERIAL: The aim of this work was, firstly, to compare different manufacturer-provided MRA sequences in a 1.0 T MR unit, with respect to the visibility of an artificial stenosis in a flow phantom and, secondly, to evaluate the same sequences in healthy volunteers with respect to S/N ratio levels and practical in vivo implementation routines. METHODS: The studied sequences were 2D and
The thesis concerns the development and application of two laser-based methods for combustion diagnostics: dual broadband rotational coherent anti-Stokes Raman spectroscopy (CARS) and laser-induced fluorescence (LIF). In efforts to increase the usefulness of the CARS technique, the applicability of a method involving a combination of the rotational CARS technique and the closely related vibration
The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. Lund University Hospital, are immunised with their own glioma cells, which have been transfected with the immunostimulatory
This paper presents global high-level synthesis (HLS) approach which addresses the problem of synthesis of conditional behaviors under resource constraints. In proposed methodology, the conditional behaviors are represented by hierarchical conditional dependency graphs (HCDG) and synthesized using derived constraints programming (CP) models. Our synthesis methods exploit multicycle operations and
Identifying genes that regulate polygenic diseases influenced by the environment such as rheumatoid arthritis (RA), has so far proven to be difficult. By using an alternative approach, i.e., linkage analysis using relevant animal models we succeeded in finding the Ncf1 gene residing in the Pia4 quantitative trait locus to be responsible for the severity of pristane induced arthritis in rats. The i
Exposure to methylene chloride produced a time and concentration related increase in liver weight. The effect was more prominent in female mice than in male. The activity of plasma butyrylcholinesterase (BuChE) increased even more than the liver weight at corresponding exposures, but only in the males. Fatty infiltration was noticeable after exposure to 75 p.p.m. and was more prominent in the fema
In this study changes in the diameter and compliance of the distal abdominal aorta (76 healthy Caucasian males, 5-71 years old) were determined non-invasively and related to age by means of an ultrasound phase-locked echo-tracking system. The diameter of the aorta increased not only in the period between 5 and 25 years of age, but also by about 30% between the ages of 25 and 71. The pressure diame
