Filtyp
This thesis examines the scholarly study of Sir Thomas Malory’s Le Morte Darthur, especially the way in which the field has been shaped by the discovery of the Winchester MS in 1934. Owing to the complex relationship between the manuscript and the printed edition of 1485, both contradictory and co-dependent, Le Morte seems to invite a number of narratives regarding its origins and originality whil
Popular Abstract in Swedish Borrelios är en fästingöverförd infektionssjukdom som orsakas av spiroketen Borrelia burgdorferi sensu lato. Borrelia infektionen är en zoonos, en sjukdom som överförs från djur till människa. I Sverige lever bakterien framför allt i smågnagare men också fåglar kan utgöra en s.k. reservoar. Reservoaren utgör källan varifrån bakterien kan infektera fästingar som tar sig Lyme borreliosis is caused by the spirochete Borrelia burgdorferi sensu lato, a bacterium with a parasitic life-style, which is transmitted between hosts by the Ixodes tick-vector. Humans will incidentally become infected. The resulting illness can involve the skin, nervous system, joints and heart. Southern Sweden has been identified as an area endemic for Lyme borreliosis. The most common clinic
C-fibre neuropeptides, such as tachykinins and calcitonin-gene related peptide (CGRP), play an important role in neurogenic inflammation. The present work deals with five different aspects of the physiology and pharmacology of C-fibres. 1) Tachykinin receptor antagonists of peptide and non-peptide nature have been employed to identify the tachykinin receptors of the rabbit iris as NK1 and NK3 type
Eicosanoids are important for a wide range of physiological and pathophysiological processes.How their essential fatty acid precursors are absorbed and tissue distributed is not well charactherized. When given orally to rats, arachidonic acid (20:4) was retained in the small intestine to a larger extent than linoleic acid (18:2).More 20:4 than 18:2 was incorporated in phospholipids (PL) of the sma
Human aquaporin 2 (AQP2) is a water channel found in the kidney collecting duct, where it plays a key role in concentrating urine. Water reabsorption is regulated by AQP2 trafficking between intracellular storage vesicles and the apical membrane. This process is tightly controlled by the pituitary hormone arginine vasopressin and defective trafficking results in nephrogenic diabetes insipidus (NDI
Molecular spiders are synthetic molecular motors featuring multiple legs that each can interact with a substrate through binding and cleavage. Experimental studies suggest the motion of the spider in a matrix is biased toward uncleaved substrates and that spider properties such as processivity can be altered by changing the binding strength of the legs to substrate [R. Pei, S. K. Taylor, D. Stefan
A supercritical fluid extraction (SFE) method has been developed for the extraction of lipids in bilberry. Experimental design was used to optimize pressure, temperature and extraction time using CO2 as solvent. Best SFE condition for total lipids was 450 bar, 60 °C and 45 min. The SFE method was compared to conventional Bligh & Dyer (B&D) extraction. The amount of fatty acid methyl esters
ANCA-associated vasculitis is commonly found in elderly patients, but there are few data concerning outcome and treatment in the highest age groups.
Purpose – The purpose of this paper is to look more closely at the residents’ attitude to individual heat metering and charging systems (IMC) of multi-family dwellings in residential properties, and to evaluate the tenant’s perception of IMC and how it may affect the continued expansion of such systems. Design/methodology/approach – The research in this paper is based on a questionnaire and interv
For triangles with linear vertex motion, common practice is to backface cull a triangle if it is backfacing at both the start and end of the motion. However, this is not conservative. We derive conservative tests that guarantee that a moving triangle is backfacing over an entire time interval and over the area of a lens. In addition, we present tests for the special cases of only motion blur and o
The photo-fragmentation of ammonia molecular clusters ionized with soft x-rays is studied for photon energies near the N-1s threshold. The fragmentation is studied with a 3D momentum mass spectrometer to access the energy and angular correlations between fragments. By choosing the cluster sizes below or above the critical size of stable dication, we investigate the coulomb explosion dynamics and t
This study investigates associations between perceived micro-level urban design qualities, the affective experience of walking, and intention to walk specific routes in the neighbourhood. A total of 106 residents assessed on-site three routes planned for walking in semi-central neighbourhoods. In the prediction of the residents’ intention to choose to walk and intention to avoid walking the route,
Pre-adsorbed branched brush layers were formed on silica surfaces by adsorption of a diblock copolymer consisting of a linear cationic block and an uncharged bottle-brush block. The charge of the silica surface was found to affect the adsorption, with lower amounts of the cationic polyelectrolyte depositing on less charged silica. Cleaning under basic conditions rendered surfaces more negatively c
The scientific objectives of the Cain mission cover areas of galactic structure and evolution, stellar astrophysics, exoplanets, solar system physics, and fundamental physics. Astrometrically, its main contribution will be the determination of millions of absolute stellar parallaxes and the establishment of a very accurate, dense and faint non-rotating optical reference frame. With a planned launc
Are people strategically ignorant of the negative externalities their activities cause the environment? Herein we examine if people avoid costless information on those externalities and use ignorance as an excuse to reduce pro-environmental behavior. We develop a theoretical framework in which people feel internal pressure ("guilt") from causing harm-to the environment (e.g., emitting carbon dioxi
Neighborhood characteristics have been associated with both depression and diabetes, but to date little attention has been paid to whether the association between depression and diabetes varies across different types of neighborhoods. This prospective study examined the relationship between depression, neighborhood deprivation, and risk of type 2 diabetes among 336,340 adults from a national-repre
Bone and soft tissue sarcomas are a group of histologically heterogeneous and relatively uncommon tumors. To explore their genetic origins, we sequenced the exomes of 13 osteosarcomas, eight myxoid liposarcomas (MLPS), and seven synovial sarcomas (SYN). These tumors had few genetic alterations (median of 10.8). Nevertheless, clear examples of driver gene mutations were observed, including canonica
