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Work in rodents has demonstrated that progenitor transplantation can achieve limited photoreceptor replacement in the mammalian retina; however, replication of these findings on a clinically relevant scale requires a large animal model. To evaluate the ability of porcine retinal progenitor cells to survival as allografts and integrate into the host retinal architecture, we isolated donor cells fro
The Timor-Alor-Pantar language family has a special place in South-East Asian linguistics; its members make up the western extreme of the Papuan language sphere. Along with an exhaustive bibliography of works on the TAP languages, this paper presents a state-of-the-art review of the ongoing documentation of the TAP language family in terms of both linguistic description and (pre-)historical recons
The @b-delayed charged particle emission from 11Li has been studied with emphasis on the three-body n@a6He and five-body 2@a3n channels from the 10.59 and 18.15 MeV states in 11Be. Monte Carlo simulations using an R-matrix formalism lead to the conclusion that the AHe resonance states play a significant role in the break-up of these states. The results exclude an earlier assumption of a phase-spac
Substantial research and development efforts are being made to add driver support systems to the arsenal of traffic safety measures. Obviously, the system cannot reduce fatalities and trauma until it is actually used. Hence, drivers’ experiences and acceptance of the system are of paramount importance. A driver support system (ISA) has been investigated by means of real life trials in Sweden, Hung
Viruses can be described as biological objects composed mainly of two parts: a stiff protein shell called a capsid, and a core inside the capsid containing the nucleic acid and liquid. In many double-stranded DNA bacterial viruses (aka phage), the volume ratio between the liquid and the encapsidated DNA is approximately 1:1. Due to the dominant DNA hydration force, water strongly mediates the inte
With the climate change and urbanization process, the frequency of the urban flooding’s occurrence has increased in the recent years. It brings great economic losses to the cities, especially to the basements of individual properties. Low Impact Development (LID), which currently advocated by more city planners for managing stormwater, is considered as a more sustainable way to mitigate urban floo
This thesis is a comparative case study about how the Swedish municipalities Malmö and Umeå address gender aspects in their comprehensive plans. It also discusses how these municipalities approach the situation of women with diverse ethnic backgrounds in their planning strategies. According to previous research, immigrant women often have different experiences of the city than other women. The the
Despite achieving sustained growth for the past two decades, Indonesia is still regarded as a moderately high-inequality country. One of the most plausible explanations in the changing pattern of its structural transformation, which could be caused as a result of increasing global integration in Indonesia. Therefore, using panel data regression, this study aims to investigate the impact of trade o
Decarbonization, digitalization and decentralisation are the most important factors presently influencing energy systems worldwide. Of those, digitalization is understudied and often only analysed from a technological perspective. Energy digitalization could however fulfil important monitoring and operational functions, in energy systems which will likely become more complex. This paper therefore
The behaviour and fate of stem cells is governed by the material properties of their surrounding microenvironment. Hence emulating the extracellular matrix poses as an attractive target for tissue engineering endeavours to create a stem cell substrate. Currently, the knowledge of the material properties is mostly limited to the macroscopic level which considerably limits the understanding of tissu
This is a comparative case study of Sweden and Brazil regarding managerial challenges and opportunities in the nonprofit sector of both countries. The purpose of this thesis is to investigate whether managers of nonprofit organizations in Sweden and Brazil rely on intrinsic or extrinsic motivation to reach the organization's objectives. Additionally, it explores the main challenges and opportu
When producing biological drugs, homogeneity within and between batches is of great importance to protect public health from sources of variability. Most biopharmaceuticals are proteins, and proteins tend to undergo post-translational modifications, such as glycosylation. As this may impact potency and immunogenicity, accurately controlling and measuring the glycosylation of a biological drug is n
In recent years, brands have increasingly embraced activism as a strategy to rebrand themselves in the marketplace, reflecting a broader trend of companies striving to resonate with consumers' evolving expectations. However, most available literature on rebranding and repositioning is inward-looking, 'outcome-driven', and diminishes the agency of the consumer; at the same time, literat
Galectins are glycan-binding proteins that can reprogram the function of many cell types. They are involved in different positive and negative physiological functions in the human body including inflammation and autophagy. Thus, they have been suggested as therapeutic targets for tumour progression and they have been proposed as biomarkers for diagnosis. Galectins bind to the carbohydrates on the
Earning conference calls is an important communication tool for companies to provide relevant information about the latest quarter based on the reported earnings. However, the research on the impact of the earning conference calls has for long been a relatively unexplored subject. This study was born out of the ambition to try and expand the research done on earnings conference calls and the possi
The purpose of this paper is to investigate one of the seven characteristics proposed by Northcott and Alkaraan (2007): the characteristic of non-programmability. This paper responds to the call for a nuanced understanding of how companies are programming strategic investment decisions (Alkaraan, 2016, p. 520). The purpose is fulfilled by conducting multiple case studies. The data collection metho
A growing environmental issue today is the amount plastic pollution in the ocean. To investigate how it might affect marine life, an important aspect is to study how plastics are transported by ocean currents and where it ends up. This can be done by use of Lagrangian simulation of plastic particles in computer ocean models. To improve the quality of the output from such simulations the number of
This dissertation aims to understand the phenomena of informal settlements and internal migration within the context of urban spaces in Mali. The design of the study is a qualitative case design using critical realism as a philosophical approach. Methods used are coding and memoing in accordance with a transcendental realism framework for qualitative research. The study found that there has been a
The objective of the present study is to outline, generate, and evaluate a series of tests, which pertains to establish if there is a relationship between speech intelligibility and presence of dead regions. An extensive speech test was constructed using low-pass and band-pass filtered City University of New York- sentences (CUNY's) and vowelconsonat- vowel-utterances (VCV's). Furthermore,
Plants need light to convert earbon dioxide to organic compounds, but when exposed to too much light the photosynthetic machinery takes damage. This is prevented by conversion of violaxanthin to zeaxanthin, which participate in a process that converts the excess light into heat. The conversion of violaxanthin to zeaxanthin is done by the enzyme violaxanthin de-epoxidase. VDE from spinach have bee
