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The three-dimensional structure of the major birch pollen allergen, the 17,500 M(r) acidic protein Bet v 1 (from the birch, Betula verrucosa), is presented as determined both in the crystalline state by X-ray diffraction and in solution by nuclear magnetic resonance (NMR) spectroscopy. This is the first experimentally determined structure of a clinically important inhalant major allergen, estimate

Ethanol can be produced from lignocellulosic biomass using steam pretreatment followed by enzymatic hydrolysis and fermentation. The sugar yields, from both hemicellulose and cellulose are critical parameters for an economically-feasible ethanol production process. This study shows that a hear-theoretical glucose yield (96-104%) from acid-catalysed steam pretreated corn stover can be obtained if x

Growth and metabolic activities of Bacillus cereus were found to cause the extraction of iron atoms from the octahedral position in mica in the kaolin sample (49%) and in the quartz sands sample (17%) after 3 months of bioleaching, while aluminium removal was only 5%. Mica destruction was detected in kaolin and quartz sands samples by X-ray diffraction analysis and also by i.r. adsorption spectros

We have recently demonstrated, that DNA ejection from bacteriophage I can be partially or completely suppressed in vitro by external osmotic pressure. This suggests that DNA ejection from phage is driven by an internal mechanical force consisting of DNA bending and DNA-DNA electrostatic repulsion energies. In the present work we investigate the extent to which DNA ejection is incomplete at zero os

In Study 1 (N = 120), pictures of violent behavior taking place within or between ethnic groups were rated under different instructions. A strong cross-over effect was found: interracial violence was reported as relatively more threatening under the instruction that the study concerned anxiety, whereas violence among Whites was reported as more threatening under the instruction that the study conc

The structures of N-t-butyl-2-(diphenylphosphino)benzylammoniumchloride and N-t-butyl-2-(diphenylphosphino)benzylaminediacetatepalladium(II) have been determined by X-ray crystallography. The Pd-complex was prepared by treating palladiumdiacetate with N-t-butyl-2-(diphenylphosphino)benzylamine in CH2Cl2 for 4 h at room temperature. The organic compound crystallises in the monoclinic space group P2

The research applies media discourse analysis and late modernity theory to the social construction of the transnational Oresund Region between the South of Sweden and East of Denmark. Based on interviews with PR sources and journalists, analysis of newspaper texts and opinion polls, the study found that despite trans-national aims the region is mainly constructed through Swedish or Danish national

In balance clinic practice, phobic postural vertigo is a term used to define a population with dizziness and avoidance behavior often as a consequence of a vestibular disorder. It has been described as the most common form of dizziness in middle aged patients in dizziness units. Anxiety disorders are common among patients with vestibular disorders. Cognitive-behavioral therapy is an effective trea

The diphosphine cis-1,3-bis[(di-tert-butylphosphino)methyl]cyclohexane (2) has been synthesised and its complexation in palladium chemistry has been investigated. Ligand 2 is capable of tricoordination, for instance as demonstrated by an X-ray crystal structure determination of the complex [Pd(2)I], and it is a rare example of a PC(sp(3))P pincer ligand. A catalytic study of the Heck reaction reve

Improving effectiveness in response to H1N1 outbreaks requires us to understand how different organisations within the outbreak coordination network work collectively to share information needed to operate at optimal level. Research for developing reliable framework for the collection of inter-organisational coordinated response data and its impact on decision-making and support system for disease

The aim of the study was to examine relationships between psychosocial family- and school environment and personality as assessed by the Junior Eysenck Personality Questionnaire (EPQ-J) and possible personality interactional effects. The study was based on 244 Swedish girls and boys, 10-19 years old, who filled in the Family- and School Psychosocial Environment (FSPE) questionnaire and the EPQ-J.

Inhibition of host-encoded targets, such as the cyclophilins, provides an opportunity to generate potent high barrier to resistance antivirals for the treatment of a broad range of viral diseases. However, many host-targeted agents are natural products, which can be difficult to optimize using synthetic chemistry alone. We describe the orthogonal combination of bioengineering and semisynthetic che

The interfacial structure of natural rubber (NR) colloids is investigated by means of cryogenic transmission electron microscopy (cryo-TEM) and electrokinetics over a broad range of KNO3 electrolyte concentrations (4-300 mM) and pH values (1-8). The asymptotic plateau value reached by NR electrophoretic mobility (mu) in the thin double layer limit supports the presence of a soft (ion- and water-pe

Combining pheromone trapping and genetic analyses can be useful whentrying to resolve complexes of closely related insect taxa that are difficult to distinguishbased on morphological characters. Nearctic and Palearctic populations of the spruceseed moth, Cydia strobilella L., have been considered taxonomically synonymoussince 1983, but more recent work revealing distinct sex pheromones for Canadia

The mevalonate synthesis pathway produces intermediates for isoprenylation of small GTPases, which are involved in the regulation of actin cytoskeleton and cell motility. Here, we investigated the role of the prenylation transferases in the regulation of the cytoskeletal organization and motility of PC-3 prostate cancer cells. This was done by using FTI-277, GGTI-298 or NE-10790, the specific inhi

The role of nurses and technicians in the treatment of ST-elevation myocardial infarction (STEMI) by primary percutaneous coronary intervention (PPCI) is vital for the success of the multidisciplinary Heart Team. Several editorials have emphasised the importance of a holistic treatment which links each step of care to the next, a chain that is essential for quality and efficacy in the management o

Acquisition of homozygous activating growth factor receptor mutations might accelerate cancer progression through a simple gene-dosage effect. Internal tandem duplications (ITDs) of FLT3 occur in approximately 25% cases of acute myeloid leukemia and induce ligand-independent constitutive signaling. Homozygous FLT3-ITDs confer an adverse prognosis and are frequently detected at relapse. Using a mou

Characterizing the sizes and interactions of macromolecules under native conditions is a challenging problem in many areas of molecular sciences, which fundamentally arises from the polydisperse nature of biomolecular mixtures. Here, we describe a microfluidic platform for diffusional sizing based on monitoring micron-scale mass transport simultaneously in space and time. We show that the global a