Sökresultat

Abstract is not available

Popular Abstract in Swedish Prostatacancer är Sveriges vanligaste cancersjukdom bland män. Många av de som diagnosticeras med prostatacancer får inga besvär men cirka 2400 män dör årligen av sjukdomen. Det finns flera behandlingsmetoder mot prostatacancer, men för kastrationsresistent prostatacancer, en avancerad form av prostatacancer, finns idag ingen botande behandling. Det utvecklas dock allt Prostate cancer is one of the major causes of cancer related deaths in men in Europe and the United States. In this doctoral thesis, radioimmunoimaging and -therapy of prostate cancer was investigated pre-clinically by targeting the human kallikrein-related peptidase 2 (hK2) with radiolabelled monoclonal antibodies. hK2 is an antigen that is over-expressed in prostatic neoplasms and is closely rel

PCR is widely employed as a rapid, sensitive and specific molecular diagnostic technique in clinical diagnosis, environmental investigations and for monitoring biotechnical processes. However, the full potential of diagnostic PCR is limited, in part, by the presence of PCR-inhibitory substances in biological samples. Among the mechanisms by which these inhibitors may act are through interfering wi

Context: With new astronomical infrared spectrographs the demands of accurate atomic data in the infrared have increased. In this region there is a large amount of parity-forbidden lines, which are of importance in diagnostics of low-density astrophysical plasmas. Aims: We present improved, experimentally determined, energy levels for the lowest even LS terms of Fe ii, Ti ii and Cr ii, along with

Popular Abstract in Swedish Glukos är kroppens viktigaste energikälla och distribueras via blodet. Hjärncellerna är helt beroende av glukos för sin energiförsörjning. Nervceller har dålig förmåga att lagra glukos och låga blodsockerhalter påverkar negativt dessa cellers funktion och kan ytterst leda till koma och död. Det är därför inte förvånande att blodsockerhalten normalt hålles inom ganska snAbstract The electrophysiological properties of insulin-secreting b-cells, glucagon-releasing a-cells and somatostation-producing d-cells in intact mouse pancreatic islets were investigated using the perforated patch whole-cell technique. It is demonstrated that it is possible to functionally identify the different cell types in situ. The ?-cells have a cell capacitance of 7.4 pF and differ from

Calculation of relative humidity and temperature in an early stage of the design process is important to avoid moisture damages in wooden walls. Previous studies show that a sufficient air flow in the air gap behind the façade panel is important to ensure a moisture safe construction. This study investigates if blind WUFI 5.0 calculations with a varied air flow in the air gap behind the façade giv

Aim This paper seeks to investigate whether alpine floras on isolated mountains in boreal forest show nestedness, and, if that is the case, to determine whether selective extinction or colonization is the likely cause of the observed patterns. Location Isolated mountains in the boreal coniferous forests of northern Sweden (province of Norrbotten, c. 66°N; 18°E). The timberline in the region probab

1. Opioid- and FMRFamide (FMRFa)-ergic systems are believed to play antagonistic behavioral roles in both higher and lower animals. In our previous experiments on a snail, behavioral choice has been demonstrated to be dependent on a balance between FMRFa and enkephalins [7]. Here, we examined if the disturbance of the balance causes changes in the activity of both systems. Opiate receptor blocker

In this paper the characteristics of the primary breakup of a liquid jet is analyzed numerically. We applied the Volumes of Fluids (VOF) approach utilizing the Direction Averaged Curvature (DAC) model, to estimate the interface curvature, and the Direction Averaged Normal (DAN) model, to propagate the interface. While being used for the first time to predict liquid atomization, this methodology sh

The sharp rise in the incidence of Alzheimer's disease (AD) at an old age coincides with a reduction in energy metabolism and core body temperature. We found that the triple-transgenic mouse model of AD (3×Tg-AD) spontaneously develops a lower basal body temperature and is more vulnerable to a cold environment compared with age-matched controls. This was despite higher nonshivering thermogenic act

Background: Strategies of habitat selection, defence, and foraging depend critically on population density and the frequency of alternative strategies: they are evolutionary games. Although commonly modelled in studies of animal behaviour, they are less frequently used to provide insights into the behaviour of plants. A 'review' and analysis of how these universal strategies apply to plants should

UNLABELLED: Persistent CB1 cannabinoid receptor activity limits neurotransmitter release at various synapses throughout the brain. However, it is not fully understood how constitutively active CB1 receptors, tonic endocannabinoid signaling, and its regulation by multiple serine hydrolases contribute to the synapse-specific calibration of neurotransmitter release probability. To address this questi

The concept of smart specialization has attracted great interest and has been adopted widely in European regional and innovation policy. Foresight is an important part of creating smart specialization strategies. However, both the smart specialization concept and foresight have been criticized for lacking an empirical and theoretical foundation that can help guide their application in practice. Th

Regular midwinter counts of waterfowl (included in theInternational Midwinter Counts, IWC, organized by whatis now Wetlands International) has been undertaken inSweden since the start in 1967 and are still going on,now as a part of the National Environmental MonitoringProgramme. After the first exploratory years includingcountry-wide surveys in 1971–1973 undertaken bothfrom the ground, the air and