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AIMS: Cancer syndromes manifest at many sites albeit with variable penetrance. Genome-wide association (GWA) studies have identified susceptibility loci shared by many types of cancer. Yet, a population level search for shared susceptibility between discordant cancers has been hampered because of lacking population sizes. METHODS: Over 1.1million patients in the nation-wide Swedish Family-Cancer D
The aim of this study was to validate the Edholm scale (Edholm, 1966) and the ISO 8996 standard (International Organization for Standardization [ISO], 1990) by comparing the metabolic rates estimated for both methods with the actual measured metabolic rate (MMeas) in 6 manual material handling tasks simulated under laboratory conditions. The metabolic rate was calculated from oxygen consumption VO
The aim of this study was to investigate construct validity and internal consistency of a modified version of the Consumer Emergency Care Satisfaction Scale used on persons accompanying emergency department patients. The sample comprised 128 persons. The results showed satisfactory reliability, and an exploratory factor analysis revealed 3 factors: caring, teaching, and clinical competence. The mo
We use a genetic algorithm to theoretically optimize several properties of extreme ultraviolet (XUV) radiation, generated as high-order harmonics in xenon and argon. We maximize the harmonic pulse energy, minimize the pulse duration or optimize the temporal coherence by varying at the same time two or three parameters that are easily accessible in experiments, related to the characteristics of the
The aim of this study was to describe experiences of physical activity, perceived meaning and importance of, and motives and barriers for participation in physical activity, among people 80 years of age and older. A qualitative design with focus-group methodology was used. The sample consisted of 20 community-living people aged 80-91 years. Data analyses revealed four themes: physical activity as
The aim of the study was to gain a theoretical understanding of parents' experiences and handling of the situation, when their foetus was diagnosed as having choroid plexus cysts, at a routine second trimester ultrasound examination. Nine couples and one mother were interviewed using one open question. Analysis method was Grounded Theory. The main concern was anxiety and the core category became n
Intraductal papillary mucinous neoplasms (IPMNs), characterized by intraductal papillary growth and thick mucin secretion, have increasingly been recognized. Despite modern preoperative evaluation, major difficulties still remain in distinguishing malignant invasive types from benign IPMNs. Following a PubMed database search, all relevant abstracts and articles on IPMN published in English and Chi
Gestures, the symbolic movements speakers perform while they speak, are systematically related to speech and language at multiple levels, and reflect cognitive and linguistic activities in non-trivial ways. This chapter presents an overview of what gestures can tell us about the processes of second language acquisition. It focuses on two key aspects, (a) gestures and the developing language system
The purpose of this study was to investigate the cause of death in subjects with α-synucleinopathies (ASs) and the confirmed presence of cardiac α-synuclein (α-syn), compared to non-AS disorders in a neuropathologically confirmed cohort. In total, 78 neuropathologically confirmed AS cases positive for cardiac α-syn were included in the study. Individuals with other neurocognitive diseases, having
