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Background. The effect of dexamethasone (Dex) on postnatal bone formation processes is known to decrease the synthesis of collagen and bone matrix, but the effect of alpha-ketoglutarate (AKG) is to induce positive effects on growth and skeletal development during postnatal life. However, the effects of Dex and AKG treatment on the prenatal processes of skeletal development have not been investigat

Ligands usually bind to proteins by displacing water from the binding site. The affinity and kinetics of binding therefore depend on the hydration characteristics of the site. Here, we show that the extreme case of a completely dehydrated free binding site is realized for the large nonpolar binding cavity in bovine beta-lactoglobulin. Because spatially delocalized water molecules may escape detect

Water–biomolecule interactions have been extensively studied in dilute solutions, crystals, and rehydrated powders, but none of these model systems may capture the behavior of water in the highly organized intracellular milieu. Because of the experimental difficulty of selectively probing the structure and dynamics of water in intact cells, radically different views about the properties of cell wa

Swedish cross-sectional survey data on young individuals aged 12-18-year-old was used to analyse school-class based peer effects in binge drinking, smoking and illicit-drug use. Significant and positive peer effects were found for all three activities. By introducing school/grade fixed effects, the estimated peer effects were identified by variation in peer behaviour across school-classes within s

The aim was to investigate the construct validity and internal consistency of the Swedish version of the Consumer Emergency Care Satisfaction Scale. The sample comprised 157 persons from an emergency department and an observation ward. The results showed satisfactory reliability, and an explorative factor analysis revealed 3 factors: Caring, Teaching, and Clinical Competence. The Swedish version o

New radiative lifetime measurements performed with time-resolved laser spectroscopy for the 6p(1/2) and 6p(3/2) levels of La III provide a unique opportunity for testing the adequacy of the relativistic Hartree-Fock approach for atomic structure calculations in this ion. As a consequence of the comparison, an extensive set of accurate f-values is provided for many La III and Lu III UV and visible

We report a strong prepulse dependence of the emission of X-rays from plasmas created by 150 fs Ti:sapphire laser pulses on solids. The laser pulses were focused onto plane samples of aluminium and vanadium with a main pulse power density of about 2.5 x 10(16) W cm(-2). By splitting off a portion of the main pulse we were able to generate a prepulse whose delay and intensity were variable relative

For ergonomics/human factors solutions to be beneficial for society and its members it is vital to apply a systems level perspective. Students who will be the future engineers, designers, and managers of socio-technical systems need to gain an understanding of how ergonomics/human factors can be integrated in the design of workplaces, organisations, products, and services. This paper gives example

This paper deals with the problem of reconstructing the locations of a number of points in space from three different images taken by uncalibrated cameras. It is assumed that the correspondences between the points in the different images are known. In the case of six points this paper shows that there are in general three solutions to the problem of determining the shape of the object, but some of

This paper provides an extensive analysis of the demand for alcohol in terms of total quantity and quantity subdivided into frequency and intensity demand. The analysis compares across alcohol types (beer, wine and spirits), alcohol drinking pattern (average drinker vs. binge drinkers) and also how these decisions differ across gender. The analysis is based on a large sample of cross-sectional dat

The first model to predict chloride ingress into concrete was presented by Collepardi in 1970, in Italian! That model was used for some 20 years for design of concrete structures before it was realized that the main parameter, the apparent chloride diffusion coefficient, is not a material property! Since then the Collepardi model has been significantly improved and developed into more or less soph

OBJECTIVE: To compare costs of transurethral prostatic resection (TURP) and transurethral microwave thermotherapy (TUMT) for symptomatic benign prostatic hyperplasia (BPH) in a randomized, controlled trial. METHODS: In 70 BPH patients all costs were calculated for management, including complications and repeat treatment, during TURP or TUMT and 24-month follow-up. Clinical outcome was judged from