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Bacterial surface protein L binds and inactivates neutrophil proteins S100A8/A9.

Finegoldia magna is an anaerobic bacterial species that is part of the normal human flora on all nonsterile body surfaces, but it is also a significant opportunistic pathogen causing a wide range of infections. Some isolates of F. magna that are more frequently associated with clinical infection express protein L, a surface protein containing multiple homologous domains (B1-B5) that bind Igs throu

Epidural lipomatosis and congenital small spinal canal in spinal anaesthesia: a case report and review of the literature.

INTRODUCTION: Complications after lumbar anaesthesia and epidural blood patch have been described in patients with congenital small spinal canal and increased epidural fat or epidural lipomatosis. These conditions, whether occurring separately or in combination, require magnetic resonance imaging for diagnosis and grading, but their clinical significance is still unclear. CASE PRESENTATION: A 35-y

When do adolescents become smokers?

Objective. To follow the development of a class of pupils' tobacco habits for seven years, and to study differences in tobacco use between girls and boys. Setting. Kronoberg County in southern Sweden. Subjects. All the approximately 2000 pupils were followed from approximately age 12 to approximately age 18. Design. Yearly cross-sectional surveys from 1994 to 2000. Each year, the pupils filled in

A Comparison of A Single and Multiphase Jets in a Crossflow Using LES

Large eddy simulations (LES) are performed for single and multiphase jets in crossflow (JICF). The multiphase JICF are compared to the single-phase case for the same momentum and mass flow ratios but with droplets of different sizes. Multiphase JICF have stronger counterrotating vortex pairs (CVPs) than a corresponding single-phase JICF. Moreover, their trajectories are higher and their induced wa

Biological effects of a disposable, canisterless negative pressure wound therapy system.

Objective: Recent developments of negative pressure wound therapy (NPWT) systems have focused on making pumps smaller, lighter, and more portable. The recently introduced PICO system manages wound fluid through a highly breathable film within the dressing, thereby negating the need for a canister, which allows greater mobility and patient concordance. The aim of this study is to compare the biolog

Impaired nerve-mediated relaxation of penile tissue from caveolin-1 deficient mice.

Caveolin-1-deficient mice are characterised by a high vascular NO production. Because NO-dependent smooth muscle relaxation is considered to play an important role in penile erection, it was hypothesized that the erectile function would be affected by genetic ablation of caveolae. This study assessed penile erectile mechanisms in caveolin-1 knockout (KO) mice ex vivo. Immunofluorescence confirmed

IL-21 and autoimmune disease - hypothesis and reality?

Previous data have indicated that IL-21 and/or IL-21R are crucial for the differentiation of naïve T cells into Th17 cells and also play a key role in the development of autoimmune disease. Given this, IL-21 and/or IL-21R are potential targets for therapy of such diseases; however, a study in this issue of the European Journal of Immunology, provides a new twist in the story as it is now shown tha

Prostacyclin reduces plasma volume loss after skeletal muscle trauma in the rat.

BACKGROUND: Trauma induces transcapillary leakage of fluid and proteins because of increased microvascular permeability. Based on studies showing that prostacyclin (PGI2) has permeability-reducing properties, in the present study, we investigated whether PGI2 reduces plasma volume (PV) loss after a nonhemorrhagic trauma. METHODS: The study was performed on anesthetized Sprague-Dawley rats exposed

Antifungal activities of peptides derived from domain 5 of high-molecular-weight kininogen.

In both immunocompromised and immunocompetent patients, Candida and Malassezia are causing or triggering clinical manifestations such as cutaneous infections and atopic eczema. The innate immune system provides rapid responses to microbial invaders, without requiring prior stimulation, through a sophisticated system of antimicrobial peptides (AMPs). High molecular weight kininogen (HMWK) and compo

Assessment and System Analysis of Industrial Waste Management

Considerable economic as well as environmental benefits can be achieved when appropriate industrial waste management is implemented. The objective of this study was to find a method of organizing a waste management system and of obtaining an overview of the whole system. The method proposed emphasizes the optimization of waste management with regard to energy, economy and environmental impact in s

Ny strategi för vetenskaplig bokpublicering vid Lunds universitet

Två förslag till en bättre publiceringsverksamhet vid Område HT och vid Lunds universitet. Rapport från projektet HT-områdets bokpubliceringar. Rapporten innehåller förutom de två förslagen också kort historisk bakgrund, nationell och skandinavisk jämförelse och inventering av HT-forskarnas publiceringar. Dessutom sammanfattas två väsentliga internationella diskussioner: hur universitetsförlagen

Introducing “medarbetarskap” as a concept facilitating work related relationships: Theoretical considerations in an airport change process.

The Swedish Air Navigation Service Provider, Luftfartsverket, together with Stockholm-Arlanda airport are implementing a new socio-technical concept called collaborative decision making. New technology and work procedures in collaborative decision making are directly affecting all organizations in an airplane turn-round process, and indirectly affecting legislators, authorities, suppliers, and pas