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Down syndrome (DS) or trisomy 21 (T21) is a leading genetic cause of intellectual disability. To gain insights into dynamics of molecular perturbations during neurogenesis in DS, we established a model using induced pluripotent stem cells (iPSC) with transcriptome profiles comparable to that of normal fetal brain development. When applied on iPSCs with T21, transcriptome and proteome signatures at
This article describes the effect of the oxidative stress inducers Angiotensin II and 6-hydroxydopamine (6-OHDA) on different cell lines. The levels of expression Angiotensin type 1 and type 2 receptors in different dopaminergic cell lines are shown. The data indicate that treatment with Angiotensin II and 6-OHDA increases the production of reactive oxygen species (ROS) and decreases cell viabilit
Background/objectives: Mycosis fungoides (MF) is a rare malignancy, with an indolent course in the early stages of the disease. However, due to major molecular and clinical heterogeneity, patients at an advanced stage of the disease have variable responses to treatment and considerably reduced life expectancy. Today, there is a lack of specific markers for the progression from early to advanced st
Previous research indicates that insulin-like growth factor binding protein 7 (IGFBP7) protein levels in breast cancer tissue and blood are prognostic. However, genetic determinants of IGFBP7 in breast cancer remain largely unexplored. We examined IGFBP7 in a cohort of 1701 patients with a first breast cancer from Sweden, enrolled prior to surgery 2002-2016 and followed for up to 15 years. Genotyp
Background: There is an urgent need for effective treatments against glioblastoma (GBM). In this trial, we investigated the efficacy and safety of an adoptive cell-based immunotherapy. Methods: Patients with newly diagnosed GBM were recruited at 4 study sites in Sweden. The patients were randomized 1:2 to receive either radiotherapy (RT), 60 Gy/30 fractions, with concomitant and adjuvant temozolom
Light microscopy has been a favorite tool of biological studies for almost a century, recently producing detailed images with exquisite molecular specificity achieving spatial resolution at nanoscale. However, light microscopy is insufficient to provide chemical information as a standalone technique. An increasing amount of evidence demonstrates that optical photothermal infrared microspectroscopy
The major histocompatibility complex (MHC) is of central importance to the immune system, and an optimal MHC diversity is believed to maximize pathogen elimination. Birds show substantial variation in MHC diversity, ranging from few genes in most bird orders to very many genes in passerines. Our understanding of the evolutionary trajectories of the MHC in passerines is hampered by lack of data on
Objectives The aim of this study was to conduct a nationwide all comer description of incidence, contemporary management and outcome in Swedish spontaneous coronary artery dissection (SCAD) patients. The incidence of SCAD as well as the management and outcome of these patients is not well described. Design A nationwide observational study. Participants and setting All patients with SCAD registered
The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. Fibroblasts constitute o
– 424 – Utbildningsplan 1. Identifikation • Programmets namn och inriktning: Musikerutbildning, musikdramatik – sång • Omfattning i högskolepoäng: 120 hp. • Nivå: A • Programkod: KAMUS. Inriktning: MUSÅ. • Utbildningsplanen är beslutad i Konstnärliga fakultetsstyrelsen den 14 februari 2007. Utbildningsplanen träder i kraft den 1 juli 2007. • Beslut om tillägg ”Musikdramatik” togs i Institutionssty
https://www.mhm.lu.se/sites/mhm.lu.se/files/utbildningsplan_a-musikerutbildning_musikdramatik_sang.pdf - 2026-07-07
Yrke – kvalif kation – rörlighet Yrkesutbildningens irrvägar Av Nils Karlson och Filippa Ronquist Näringslivets forskningsinstitut Yrkesutbildingens irrvägar N äring slivets forskning sinstitut I rapporten Yrkesutbildningens irrvägar görs en systemanalys av svensk yrkesutbild- ning, med fokus på följande frågeställningar: – Hur är yrkesutbildningssystemet utformat och finansierat? – Möjliggör och
https://www.soch.lu.se/sites/soch.lu.se/files/yrkesutbildningens_irrvagar.pdf - 2026-07-07
1 A Gap in the Corporate Responsibility to Respect Human Rights Radu Mares First published as Radu Mares, ‘A gap in the corporate responsibility to respect human rights’, Monash University Law Review, vol. 36.3, pp. 33- 83 (2010) * This is the final version of the article. For references to exact pages, please refer either to this on-line document or to the formatted version in the journal. Abstra
https://rwi.lu.se/app/uploads/2012/08/A-Gap-in-the-Corporate-Responsibility.pdf - 2026-07-07
Background: The Autism- Tics, ADHD and other Comorbidities inventory (A-TAC) has been validated in epidemiological data. However, validation against clinical diagnostic assessments in a population-based sample has been lacking, limiting the implications for clinical practice, clinical research and public health decisions. Methods: Study participants were recruited from the longitudinal Child and A
Lavalgenerationen Red. Niklas Selberg & Erik Sjödin 2 0 1 0 - T A L E T S D O K T O R S A V H A N D L I N G A R I A R B E T S R Ä T T L avalgenerationen ISBN: 978-91-7737-087-1 R ed. N . Selberg & E . Sjödin 2010-TALETS ARBETSMARKNAD och arbets rätt har präglats av omvälvande förändringar. I denna antologi belyses hur dessa förändringar kräver nya analyser av delvis nya frågeställningar. 14 perso
https://www.soclaw.lu.se/sites/soclaw.lu.se/files/svenaeus_lavalgenerationen.pdf - 2026-07-07
Kursguide - Course Syllabus • Fastställande Kursplanen är fastställd av Samhällsvetenskapliga fakultetens styrelse 2012-05- 03 och senast reviderad 2014-06-10 av Styrelsen för institutionen för service management och tjänstevetenskap. Den reviderade kursplanen gäller från och med 2014-08-01. Allmänna uppgifter Kursen är valbar som en av två kurser under termin fem för samtliga inriktningar inom ka
https://www.ses.lu.se/sites/ses.lu.se/files/kp-ksma52-ht14.pdf - 2026-07-07
Här hittar du alla LTH-relevanta utlysningar. AMBER:s utlysning för postdoktorer inom biologisk avbildningDet EU-finansierade forskningsprojektet AMBER, Advanced Multiscale Biological imaging with European Research infrastructures, utlyser cirka fyra tjänster i sin sista utlysning för postdoktorer. Varje tjänst är finansierad i 36 månader.Forskare som har en doktorsexamen inom fysik, kemi, medicin
https://www.lthin.lth.se/forska/utlysningar/alla-aktuella-utlysningar - 2026-07-07
Microsoft Word - FINAL.doc 1 EVALUATING THE SUSTAINABILITY VALUE MAP: A case study of Sagene Urban District, Oslo, Norway. Camilla Skjerve-Nielssen email: cami_sn@hotmail.com A THESIS Submitted to Lund University Centre for Sustainability Studies In partial fulfilments of the requirements for the degree Master of Science Lund University International Master’s Programme in Environmental Studies and
https://www.lumes.lu.se/sites/lumes.lu.se/files/skjerve-nielssen_camilla.pdf - 2026-07-07
resurser.xlsx Laboratorier och utrustning vid Geologiska institutionen, Lunds universitet 2012 Resurs/utrustning Utrustning (ev. specificering) Kapacitet/möjligheter Kontaktperson Kommentar Ar-‐Ar-‐laboratorium Micromass-‐5400 Gas Source Mass Spectrometer Datering av K-‐haltiga mineral och bergarter Anders Scherstén http://www.geol.lu.se/ar/ C14-‐laboratorium C14-‐datering
https://www.geology.lu.se/sites/geology.lu.se/files/georesurser.pdf - 2026-07-07
