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PHENIX measurements of 3D emission source function in Au-Au collisions at sqrt(s) = 200 GeV

A state-of-the-art 3D source imaging technique is used to extract the 3D two-pion source function in central and mid-central Au+Au collisions at GeV. The source function indicates a previously unresolved non-Gaussian tail in the directions of the pion pair transverse momentum (out) and along the beam (long). Model comparisons give robust estimates for several characteristics of the emission source

Studies of laminin a2 chain deficient mice -muscle sparing, charaterization of Cib2 and defective spermatorgenesis

Mutations in the gene encoding laminin α2 chain, an extracellular matrix protein mainly expressed in the neuromuscular system, cause a severe form of muscular dystrophy, congenital muscular dystrophy type 1A (MDC1A). Laminin α2 chain is associated to the muscle fibers by two major receptors, where one of them, integrin α7β1, is diminished upon laminin α2 chain deficiency. The majority of the skele

Genetics of Type 2 Diabetes and Metabolic Syndrome: From Genome Wide Linkage Scan and Candidate Genes to Genome Wide Association Studies

Type 2 diabetes (T2D) and metabolic syndrome (MetS) are major health problems associated with cardiovascular disease. Both diseases are influenced by a combination of genetic and environmental factors. The aim of this thesis was to identify genetic risk factors for T2D, particularly T2D associated with obesity, and for MetS. To achieve this goal, we 1) followed-up a region linked to obese T2D in a

The Anatomy and Physics of Z(DR) Columns: Investigating a Polarimetric Radar Signature with a Spectral Bin Microphysical Model

Polarimetric radar observations of deep convective storms frequently reveal columnar enhancements of differential reflectivity Z(DR). Such "Z(DR) columns" can extend upward more than 3 km above the environmental 0 C level, indicative of supercooled liquid drops being lofted by the updraft. Previous observational and modeling studies of Z(DR) columns are reviewed. To address remaining questions, th

Carbamylation-Dependent Activation of T Cells: A Novel Mechanism in the Pathogenesis of Autoimmune Arthritis

The posttranslational modification of proteins has the potential to generate neoepitopes that may subsequently trigger immune responses. The carbamylation of lysine residues to form homocitrulline may be a key mechanism triggering inflammatory responses. We evaluated the role of carbamylation in triggering immune responses and report a new role for this process in the induction of arthritis. Immun

Systematic measurements of light vector mesons at RHIC-PHENIX

The PHENIX experiment at RHIC has measured and ω meson production in p+p, d+Au and Au+Au collisions for GeV at mid-rapidity. Systematic measurements of light vector mesons for several decay channels provide information about properties of the strongly interacting matter produced in relativistic heavy-ion collisions. We present transverse momentum spectra and nuclear modification factors for and ω

On the Reliability of Mapping Studies in Software Engineering

Background: Systematic literature reviews and systematic mapping studies are becoming increasingly common in software engineering, and hence it becomes even more important to better understand the reliability of such studies. Objective: This paper presents a study of two systematic mapping studies to evaluate the reliability of mapping studies and point out some challenges related to this type of

Vortex Ring Formation in the Left Ventricle of the Heart: Analysis by 4D Flow MRI and Lagrangian Coherent Structures.

Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an optimized mechanism for blood transport, and that the volume of the vortex ring is an important measure. However, due to lack of quantitative methods, the volume of the vortex ring has not previously been studied. Lagrangian Coherent Structures (LCS) is a new flow analysis method, which enables in vi

Differences in the radiological characteristics between post-traumatic and non-traumatic knee osteoarthritis.

Osteoarthritis (OA) of the knee can be defined as primary (non-traumatic) or secondary (post-traumatic). Both non-traumatic OA and post-traumatic OA have been described predominantly in the medial compartment of the knee. The objective of this study was to compare the location of structural radiographic changes in non-traumatic OA and post-traumatic OA. A non-traumatic cohort, consisting of 155 pa

Adaptive methods for sequential importance sampling with application to state space models

In this paper we discuss new adaptive proposal strategies for sequential Monte Carlo algorithms—also known as particle filters—relying on criteria evaluating the quality of the proposed particles. The choice of the proposal distribution is a major concern and can dramatically influence the quality of the estimates. Thus, we show how the long-used coefficient of variation (suggested by Kong et al.

The Role of National Biomass Action Plans in Coordinating the National Bioenergy Activities

The EU has recently put forward an integrated proposal for “Climate Action – Energy for a Changing World”, which includes concrete measures on how to meet the ‘energy and climate change package’ targets of 2020. The challenge is how these targets can be reached, and how bioenergy can meet the expectations given to it. The EU Biomass Action Plan (BAP) emphasises the need for a coordinated approach

Gender Bias - The Insoluble Problem?

The issue and distribution of IT and IS students and professionals as dependent on Gender Bias is discussed. Background and examples are presented from the IT British Industry; the UK and the Swedish Educational sectors.

Analysis of admission control mechanisms using non-linear control theory

All service control nodes can be modelled as a server system with one or more servers processing incoming requests. In this paper we show how non-linear control theory may be used when analyzing admission control mechanisms for server systems. Two models are developed, one linear and one non-linear. We show that, due to the non-linearities appearing in a real server system, linear control theory i

Historical Dictionary of Scandinavian Cinema

Scandinavian cinema—consisting of films produced in Norway, Sweden, Denmark, Finland, and Iceland—has been the source of some of the world's most interesting films—The Seventh Seal, Dancer in the Dark, and The Girl with the Dragon Tattoo—and most influential directors—Ingmar Bergman and Lars von Trier. The Historical Dictionary of Scandinavian Cinema covers the history of the Nordic countries thro

Principles and nomenclature for the quantification of light

This chapter does not deal with any practical aspects of light measurement, only with theoretical concepts. The following concepts are explained: energy fluence, energy fluence rate, photon fluence, photon fluence rate, radiance and mol, as well as the following superfluous or obsolete terms and synonyms: actinic flux, space irradiance, scalar irradiance, spherical irradiance, vectorial irradiance