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Long-term evolution of three-planet systems to the post-main sequence and beyond

We study the stability of systems of three giant planets orbiting 3-8 M☉ stars at orbital distances of >10 au as the host star ages through the main sequence (MS) and well into the white dwarf (WD) stage. Systems are stable on the MS if the planets are separated by more than ~9 Hill radii. Most systems surviving the MS will remain stable until the WD phase, although planets scattered on to small p

Attosecond pulses by high-order harmonic generation in gases

In this paper, we review the physics of harmonic generation in gases and production of short attosecond pulses. Different methods to ensure a sufficient degree of synchronization, for example, selecting the cutoff region of the spectrum or compressing of attosecond pulses with apertures and metallic filters are presented

X-ray-emission-threshold-electron coincidence spectroscopy

Using a penetration-field threshold photoelectron (TPE) analyzer and efficient photon detectors X-ray-emission-threshold-electron coincidence (XETECO) spectroscopy has been developed to a point where peak shape analysis becomes meaningful. The spectra can, on the present level of accuracy, be interpreted as conventional TPE spectra free from post collision interaction effects. For the neon atom an

Production, characterization and use of monoclonal antibodies against the major extracellular human cysteine proteinase inhibitors cystatin C and kininogen

Murine monoclonal antibodies against the major cysteine proteinase inhibitors of human biological fluids, cystatin C and kininogen, were produced. The cystatin C antibody, HCC3, with a Ka of 2times107 l/mol, increased the inhibition of papain by cystatin C and was suitable for use in immunoblotting, immunohistochemistry and in the construction of a sensitive sandwich enzyme immunoassay for quantif

Oxidized alpha(1)-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema

Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R. Oxidized alpha(1)-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema. Am J Physiol Lung Cell Mol Physiol 297: L388-L400, 2009. First published June 12, 2009; doi:10.1152/ajplung.90373.2008.-alpha(1)-Antitrypsin ( AT) is a major elastase inhibitor within the lun

Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity.

Objective: The insulin responsive adiponutrin (PNPLA3 or ADPN) gene shows association with obesity and in vitro adipocyte lipolysis. This study aimed to replicate the association between PNPLA3 variants and obesity, and to investigate their effect on insulin resistance and beta-cell function. Methods: rs738409 (Met148Ile) and rs2072907 (C to G) were genotyped using TaqMan allelic discrimination as

Allergen-induced eosinophil cytolysis is a primary mechanism for granule protein release in human upper airways

Cytotoxic eosinophil granule proteins are considered important in the pathogenesis of allergic airway diseases such as rhinitis and asthma. To explore the cellular mechanisms behind eosinophil granule release in human allergic airways, 16 symptom-free patients with seasonal allergic rhinitis were challenged daily with allergen during 1 wk. Nasal lavage samples and biopsies, obtained before and 24

Influence of self-registration on audit participants and their non-participating colleagues - A retrospective study of medical records concerning prescription patterns

Objective. To compare participants and non-participants early in the process of an audit on treatment of respiratory tract infections (RTIs) and to analyse any effect of the actual self-registration on the prescription of antibiotics in both groups. Design. All 80 general practitioners (GPs) at 14 health centres were invited to audit their use of antibiotics and 45 agreed to participate. There wer

Radiative lifetime measurements in TmIII with time-resolved laser spectroscopy and comparisons with HFR calculations

Natural radiative lifetimes of eight levels in Tm m were measured with the time-resolved laser-induced fluorescence (LIF) technique. Free doubly ionized thulium ions were obtained in a laser-produced plasma. Three even-parity levels were excited from the ground state with one-photon excitation, using a laser system generating pulses of 1 ns duration. Five odd-parity levels were excited from the gr

Photodynamic therapy of nodular basal cell carcinoma with multifiber contact light delivery

To overcome the limited treatment depth of superficial photodynamic therapy we investigate interstitial light delivery. In the present work the treatment light was delivered using a system in which three or six clear-cut fibers were placed in direct contact with the tumor area. This placement was thought to represent a step toward general purpose interstitial PDT. Twelve nodular basal cell carcino

Lexical inferencing procedures in L3 Italian

This study is aimed at investigating and describing the different procedures of foreign language learners of Italian when they infer the meaning of unknown words in a written authentic text. Vocabulary is a crucial component in the learning process of a foreign language and many studies show that lexical inferencing is one of the most important strategies when foreign language learners encounter u

Uncertainty of oscillator strengths derived from lifetimes and branching fractions

A widely used method for determination of transition probabilities and oscillator strengths is based on measurements of branching fractions and radiative lifetimes. In the present work the different sources of uncertainty in branching fraction measurements using Fourier transform spectroscopy and lifetime measurements using laser induced fluorescence are discussed. A detailed description is presen

Analysing analyses-An approach to combining several risk and vulnerability analyses

The Swedish county council Region Skane is developing work processes for iterative risk and vulnerability analyses. This will be arranged in a distributed bottom-up manner, where analyses are performed and results reported through three hierarchical levels, ending at a central unit within the county council organisation. That unit is responsible for three tasks: 1) Establish a summary of the risks

Placed in homecare: Living an everyday life restricted by dependence and monitoring

Through a sociological case study this article analyses how, seen from a relational perspective, everyday life for elderly people receiving care in their own homes is lived with dependence on health-care professionals. The healthcare professionals’ time and tasks are assigned and allocated in advance so that the elderly people are neither allowed nor able to vary their response in relation to the

Cytoskeletal and contractile proteins in detrusor smooth muscle from bladders with outlet obstruction--a comparative study in rat and man

Detrusor biopsies were obtained from patients with urinary outlet obstruction due to prostatic enlargement and from age-matched control patients. The relative amounts of actin and myosin and their isoforms, as well as desmin and filamin were determined and compared with corresponding results from bladders from control rats and rats with 10 days of experimental outlet obstruction of the urinary bla