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A group of oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy. The estimations have been based on current statistics of tumour incidence, number of patients potentially eligible for radiation treatment, scientific support from clinical trials and model dose planning studies and knowledge of the doseresponse relations of different tu
The kinetics of furfural inhibition of the enzymes alcohol dehydrogenase (ADH; EC 1.1.1.1), aldehyde dehydrogenase (AlDH; EC 1.2.1.5) and the pyruvate dehydrogenase (PDH) complex were studied in vitro. At a concentration of less than 2 mM furfural was found to decrease the activity of both PDH and AlDH by more than 90%, whereas the ADH activity decreased by less than 20% at the same concentration.
We present an experimental comparison of magnetoconductance fluctuations measured in the ballistic, quasiballistic, and diffusive scattering regimes of semiconductor devices. In contradiction to expectations, we show that the spectral content of the magnetoconductance fluctuations exhibits an identical fractal behavior for these scattering regimes and that this behavior is remarkably insensitive t
A reduced protein model with five to six atoms per amino acid and five amino acid types is developed and tested on a three-helix-bundle protein, a 46-amino acid fragment from staphylococcal protein A. The model does not rely on the widely used Go approximation, which ignores non-native interactions. We find that the collapse transition is considerably more abrupt for the protein A sequence than fo
We studied the following in normo- and microalbuminuric hypertensive type 2 diabetic patients: 1) transcapillary escape rate of albumin (TERalb) and 2) expression of mRNA slit diaphragm and podocyte proteins in renal biopsies. Normoalbuminuric subjects had renal cancer, and kidney biopsy was performed during surgery. TERalb was evaluated by clearance of I-125- albumin. Real-time PCR of mRNA slit d
The use of water mist for fire extinguishment has increased rapidly in recent years. The main reason is the abandonment of halon-based extinguishing systems in favour of environmentally friendlier systems. Furthermore the use of water mist systems has spread from mainly marine applications to also include the protection of buildings. The main problem in this regard is to verify the effectiveness o
The high cost of photovoltaic modules motivates the use of reflectors to increase the electricity production. The system geometry of static low-concentrating PV systems for building-integration with parabolic aluminium reflectors was optimised for maximum annual electricity production. The optical efficiency of systems with different geometries was calculated from short-circuit current measurement
Interaction effects of UV-B and CO2 on three lichens species, Cladonia arbusculo, Cetraria islandica and Stereocaulon paschale, from two latitudinal sites, 68N and 56N, were studied in a laboratory experiment. The response of the plants was recorded by measuring their chlorophyll fluorescence. All species had a similar response to enhanced UV-B depending on the latitude from which the population c
Sixty-two patients with newly diagnosed sarcoidosis were examined with fibreoptic bronchoscopy, endobronchial biopsies and bronchoalveolar lavage (BAL) were analysed. Epithelioid granulomatosis in endobronchial biopsies were found in 28 (45%) of the patients (BPOS). The patients in this BPOS group showed higher inflammatory activity in BAL fluid compared to those with negative biopsies (BNEG), wit
Popular Abstract in Swedish En simuleringsmodell, FARMFLOW, utvecklades för att beräkna förråd, flöden och balanser av fosfor (P), zink (Zn) och kadmium (Cd) på mjölkgårdar. De simulerade kontinuerliga förändringarna av ämnesförråden gör det möjligt att utvärdera de långsiktiga effekterna av olika skötselstrategier. Fältdata från en svensk försöksgård, Öjebyn, användes för att parameterisera FARMFA simulation model, FARMFLOW, was developed for the calculation of phosphorus (P), zinc (Zn) and cadmium (Cd) stocks, flows and balances in different parts of a dairy farming system. The simulated continuous change in element stocks within the farming system enables evaluation of the long-term effects of management practices. The FARMFLOW model reproduces feedback mechanisms of the internal cyclin
Maternal counting of fetal movements is increasingly used as a clinical method for assessment of fetal health. The present study established normal limits for two methods of subjective fetal movement recording. Four hundred-and-seventeen randomly selected women with low-risk pregnancies recorded the time necessary for 10 fetal movements every morning and also the number of fetal movements during 1
The Fourier transform gas-phase IR spectrum of isoxazole, C3H3NO, between 550 and 1700 cm(-1) was measured with a resolution of ca. 0.003 cm(-1). Ten fundamental bands in the region 800-1700 cm(-1) have been analyzed by the Watson Hamiltonian model to yield upper state spectroscopic constants. A number of local resonances have been identified in the bands and explained qualitatively, and the unobs
In 48 patients with a history of a pneumococcal bacteremia, serum taken during the acute phase of the infection was analyzed for IgG and IgG subclasses. Once the patients were free of infection, a serum sample was analyzed for IgG, IgG subclasses, IgA and IgM. In an additional 20 patients, it was only possible to analyze serum from the infection-free phase. Seventeen of 48 (35%) patients had reduc
Fungal (acetate-in-ergosterol incorporation) and bacterial (leucine/thymidine incorporation) growth resulting from alfalfa (C/N = 15) and barley straw (C/N = 75) addition was studied in soil microcosms for 64 days. Nitrogen amendments were used to compensate for the C/N difference between the substrates. Fungal growth increased to a maximum after 3–7 days, at five to eight times the controls, foll
We prove a general atomic decomposition theorem for weighted vector-valued Bergman spaces, which applies to duality problems and to the study of compact Toeplitz type operators.
Background: Pancreatic acinar-like metaplasia has previously been described in the gastric mucosa and in the distal part of the oesophagus. The resemblance to pancreatic acinar cells prompted us to study the possible occurrence of secretory pancreatic proteins in these cells. Methods: Seven specimens obtained from the distal oesophagus at gastroscopy where routine microscopy showed pancreatic acin
