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1. The amino acid l-3,4-dihydroxyphenylalanine (l-DOPA) was extracted from tentacles of the sea anemone Metridium senile and from brains of the crayfish Pacifastacus leniuscuius.2. The identity of l-DOPA was ascertained by gas chromatography-mass spectrometry as the heptafluorobutyryl iso-butyl ester derivative. Dopa is identified with GC-MS for the first time and the derivatization is a novel mod

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Red kidney beans (Phaseolus vulgaris) processed to differ in distribution and content of indigestible carbohydrates were used to study hindgut fermentability and production of short-chain fatty acids (SCFA). Bean flours with low or high content of resistant starch (RS), mainly raw and physically-inaccessible starch, were obtained by milling the beans before or after boiling. Flours containing retr

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Background: Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries due to increased migration and travel. Few studies of the clinical management of cutaneous, mucocutaneous and visceral leishmaniasis in non-endemic regions have been published to d

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The southern slopes of the mountain ridge Kolmarden along the northern border of the province Ostergotland ill south-eastern Sweden have a very rich flora and varied geomorphology. Several rare and locally endemic microspecies of Hieracium have been described or reported from the area but no hieraciologist has visited the region since c. 1930. In 2004, the present author walked c. 50 km in this ar

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We investigated the effects of a single course of antenatal betamethasone on neonatal somatic and brain development. On day 20 of gestation, pregnant rats were injected with either with 170 mu g kg(-1) body weight of betamethasone ("clinically-equivalent dose," equivalent to 12 mg twice, 24 hours apart) or half this dose or vehicle. Pups (8-11 animals per experimental group per time-point per gend

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The MAKEDEP model is used to reconstruct the time-series input files of deposition, forest growth, uptake and litterfall needed to run the dynamic biogeochemical model SAFE. The amounts and timing of N made available for tree growth is what determines most of the model output. In this paper, the sensitivity Of MAKEDEP to various amounts and timing of N availability, including increased supplies of

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Objective: To describe the development and evaluation of the content and face validity and test-retest reliability of a disease-specific questionnaire that measures patient-reported outcomes and experiences for the Swedish National Diabetes Register for adult patients who have type 1 or type 2 diabetes. Methods: In this methodological study, a questionnaire was developed over four phases using an

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BACKGROUND: The gene encoding oestrogen receptor alpha (ESR1) appears to regulate bone mineral density (BMD) and other determinants of osteoporotic fracture risk.OBJECTIVE: To investigate the relation between common polymorphisms and haplotypes of the ESR1 gene and osteoporosis related phenotypes in a population based cohort of 3054 Scottish women.RESULTS: There was a significant association betwe

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Traditional linkage analysis and genome-wide association studies have identified HLA and a number of non-HLA genes as genetic factors for islet autoimmunity (IA) and type 1 diabetes (T1D). However, the relative risk associated with previously identified non-HLA genes is usually very small as measured in cases/controls from mixed populations. Genetic associations for IA and T1D may be more accurate

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BACKGROUND: The molecular chaperone heat shock protein-90 (Hsp90) is a promising cancer drug target, but current Hsp90-based therapy has so far shown limited activity in the clinic.METHODS: We tested the efficacy of a novel mitochondrial-targeted, small-molecule Hsp90 inhibitor, Gamitrinib (GA mitochondrial matrix inhibitor), in the Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model. Th

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Silicon is a promising candidate to substitute or complement graphite as anode material in Li-ion batteries due, mainly, to its high energy density. However, the lithiation/delithiation processes of silicon particles are inherently related to drastic volume changes which, within a battery's physically constrained case, can induce significant deformation of the fundamental components of the battery

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During the last decades of the twentieth century, Western philosophy saw a renewed interest in religion. This ‘turn to religion’ was in many ways prompted by concrete geopolitical developments, such as the surge of religious fundamentalism or the new visibility of religious expressions and symbols in societies that had long conceived of themselves as profoundly secular. At about the same time, a g

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Abstract Purpose: This thesis, first, sets out how the collective action strategies of prime movers and the manner in which they form networks affect the pace of legitimacy of a newly emerging bioenergy system. Under the light of this information, the second purpose is to see if it is possible to provide some lessons and good examples of networking strategies for prenatal or infant bioenergy case

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Vi tar vår utgångspunkt i skolans roll som förmedlare av demokratiska värderingar. Vi studerar olika sätt att se på begreppet demokrati och problematiken i relationer mellan demokrati och skolan. Vi använder ett konstruktionistiskt perspektiv, där vi betonar vårt förhållande till forskningsprocessen. Vi betonar även svårigheterna i att särskilja delar i uppsatsen, så som metod, teori och empiri.

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Though the practice of genocide traces its roots back to the atrocities committed in the ancient times, however, the international community has shown its reluctance to acknowledge the existence of that horrific crime. The impunity for the Armenian genocide perpetrated by the Young Turks of Ottoman Empire in 1915 had a significant impact on Adolf Hitler who referred to the Ottoman killings of Arme

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This thesis is focused on the lack of investment in the human security of the marginalized Hazara minority of Afghanistan. Human security is a relatively new concept over which there is considerable debate and this thesis presents a discussion of various debates regarding human security and peacekeeping before taking a firm stance in the debates, emphasizing the importance of investing in the huma