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The in vivo production of thromboxane and prostacyclin was studied by measurements of their major urinary metabolites in eight patients undergoing total hip arthroplasty. Specific methods based on gas chromatography-mass spectrometry were used to measure the urinary excretion of 2,3-dinor-TxB2 and 2,3-dinor-6-keto-PGF1 alpha. The excretion of these metabolites increased about 10-fold during the in
A well-orchestrated inflammatory reaction involves the induction of effector functions and, at a later stage, an active downregulation of this potentially harmful process. In this study we show that under proinflammatory conditions the noncanonical Wnt protein, Wnt5a, induces immunosuppressive macrophages. The suppressive phenotype induced by Wnt5a is associated with induction of IL-10 and inhibit
CONTEXT: Prior studies have demonstrated conflicting results regarding how much information novel biomarkers add to cardiovascular risk assessment. OBJECTIVE: To evaluate the utility of contemporary biomarkers for predicting cardiovascular risk when added to conventional risk factors. DESIGN, SETTING, AND PARTICIPANTS: Cohort study of 5067 participants (mean age, 58 years; 60% women) without cardi
B cell homeostasis is regulated by multiple signaling processes, including nuclear factor-kappaB (NF-kappaB), BAFF-, and B cell receptor signaling. Conditional disruption of genes involved in these pathways has shed light on the mechanisms governing signaling from the cell surface to the nucleus. We describe a novel mouse strain that expresses solely and excessively a naturally occurring splice va
Variations in serum prostate-specific antigen (PSA) have been ascribed to A/G nucleotide polymorphisms located at -158 bp (rs266882) and -4643 bp (rs925013), relative to the transcription start site within the promoter of the PSA gene. PSA is also an androgen receptor target (AR) gene and polymorphisms in AR gene are known to affect AR function. Our objective was to compare the impact of these A/G
As oncological treatment might impair the patients' fertility, male cancer patients are offered to cryopreserve semen prior to treatment. Impaired sperm DNA quality is associated with reduced fertility, and in case of assisted reproduction, sperm DNA integrity may have an impact on choice of method. Therefore, we have assessed sperm DNA integrity in cancer patients, comparing pre- and post-treatme
Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis (RA) with both anti-citrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deiminas
OBJECTIVE: Chimney grafts have proven useful for urgent endovascular repair of juxtarenal aortic aneurysms. Stenting of juxtarenal aortic occlusive disease is not routinely advocated due to the risk of visceral artery obstruction. We report on the potential applicability of chimney grafts in 10 patients with juxtarenal aortic stenosis or occlusion. To our best knowledge, chimney grafts have not be
Although Parkinson's disease is a movement disorder, in many patients cognitive dysfunction is an important clinical sign. It is not yet clear whether this is attributable solely to a decrease in dopamine levels, or whether other neurotransmitter systems might be involved as well. In the present study, the importance of the mesocorticolimbic dopamine pathway and a possible convergence with forebra
Recently, Burger et al. (2011) developed a new 1-D SST model which allows for more realistic predictions of the sludge settling behaviour than traditional 1-D models used to date. However, the addition of a compression function in this new 1-D model complicates the model calibration. This study aims to report advances in the calibration of this novel 1-D model. Data of the evolution of the sludge
Approaches to determining the factuality of diagnoses and findings in clinical text tend to rely on dictionaries of marker words for uncertainty and negation. Here, a method for semi-automatically expanding a dictionary of marker words using distributional semantics is presented and evaluated. It is shown that ranking candidates for inclusion according to their proximity to cluster centroids of se
The 65 kDa isoform of human glutamate decarboxylase (GAD65) is a major autoantigen in type 1 diabetes (T1D). In the present study, we have developed a sensitive sandwich time-resolved fluorescence immunoassay (TRFIA) for the quantification of GAD65 in cell extracts, cell media and serum. The monoclonal antibody GAD-6 is used to selectively capture GAD65 but not the slightly larger isoform GAD67, a
Tarmbakterier orsak till dagens ohälsa? – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Tarmbakterier orsak till dagens ohälsa? 2013-11-15 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Förr var det infektionssjukdomar som främst hotade
https://www.vetenskaphalsa.se/tarmbakterier-orsak-till-dagens-ohalsa/ - 2026-07-05
Träffsäkra diagnoser med AI vid psykisk ohälsa – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Träffsäkra diagnoser med AI vid psykisk ohälsa 2023-02-28 Foto: iStock/NickyLloyd Nästan hälften av alla sjukskrivningar beror idag på mental ohälsa. Inför vårdbesök uppmanas
https://www.vetenskaphalsa.se/traffsakra-diagnoser-med-ai-vid-psykisk-ohalsa/ - 2026-07-05
Transplantera näthinna mödosamt forskningsarbete – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Transplantera näthinna mödosamt forskningsarbete 2011-06-07 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. I näthinnan sitter våra synceller
https://www.vetenskaphalsa.se/transplantera-nathinna-modosamt-forskningsarbete/ - 2026-07-05
Vad gör demenssjukdomar med våra hjärnor? – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Vad gör demenssjukdomar med våra hjärnor? 2018-09-24 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Illustration: istock.com/wildpixel – Vi måste f
https://www.vetenskaphalsa.se/vad-gor-demenssjukdomar-med-vara-hjarnor/ - 2026-07-05
Vem blir sjuk och varför? – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Vem blir sjuk och varför? 2016-11-02 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Jonas Manjer installerades som professor i kirurgi den 14 oktober vid Lunds uni
https://www.vetenskaphalsa.se/vem-blir-sjuk-och-varfor/ - 2026-07-05
Virtuell demenssimulator ökar kunskapen om kognitiv sjukdom – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Virtuell demenssimulator ökar kunskapen om kognitiv sjukdom 2024-09-20 Maria Hedin och Joakim Eriksson har utvecklat en VR-produkt som simulerar hur världen ter s
https://www.vetenskaphalsa.se/virtuell-demenssimulator-okar-kunskapen-om-kognitiv-sjukdom/ - 2026-07-05
RHB B14 Litteraturlista Humaniora och teo log i Centrum fö r teo log i och re l ig ionsvetenskap Litteraturlista för RHB B14 Religionshistoria och religionsbeteendevetenskap: Religion och politik, 7,5 hp, VT 2015 fastställd av institutionsstyrelsen 2013-11-20 och på prefektens uppdrag bekräftad av studierektor 2014-12-10 Bauman, Whitney, Richard Bohannon II och Kevin O’Brian (2011). Grounding Reli
https://www.ctr.lu.se/media/utbildning/dokument/kurser/RHBB14/20151/RHB_B14_Litteratur.pdf - 2026-07-05
