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Historian David Lowenthal (1985) has pointed out the past is often perceived and represented as “a foreign country” in which cultural heritage is implicitly understood to be bound to geographical territories and associated notions of what it implies to have roots, an identity, and a place in which to belong. This is the paradigmatic background against which so many heritage museums have been found

Endocrine disrupting chemicals (EDCs) from the environment are associated with reproductive abnormalities (i.e. decreased sperm concentration; increased endometriosis) and alterations of the cardiovascular system (i.e. increased blood pressure and risk of coronary disease). Some phthalates esters have been identified as EDCs, for which inhalation is considered as one of the routes of exposure. How

This letter presents the first measurement of jet mass in Pb–Pb and p–Pb collisions at sNN=2.76 TeV and sNN=5.02 TeV, respectively. Both the jet energy and the jet mass are expected to be sensitive to jet quenching in the hot Quantum Chromodynamics (QCD) matter created in nuclear collisions at collider energies. Jets are reconstructed from charged particles using the anti-kT jet algorithm and reso

Purpose: Dysfunctional proteostasis, with decreased protein degradation and an accumulation of ubiquitin into aggregated protein inclusions, is a feature of neurodegenerative diseases. Identifying new potential biomarkers in cerebrospinal fluid (CSF) reflecting this process could contribute important information on pathophysiology. Experimental design: A developed method combining SPE and PRM-MS i

The gut microbiomes of birds and other animals are increasingly being studied in ecological and evolutionary contexts. Numerous studies on birds and reptiles have made inferences about gut microbiota using cloacal sampling; however, it is not known whether the bacterial community of the cloaca provides an accurate representation of the gut microbiome. We examined the accuracy with which cloacal sw

An approach to reduce CO2 emissions while simultaneously keeping the soot emissions down from compression ignition (CI) engines is to blend in short chained oxygenates into the fuel. In this work, two oxygenated fuel blends consisting of diesel, gasoline and ethanol (EtOH) in the ratio of 68:17:15 and 58:14:30 have been utilized and studied in a single cylinder light duty (LD) CI engine in terms o

Background: Analyzing Body Mass Index as a didactical example, the study by Evans, Williams, Onnela, and Subramanian (EWOS study) introduce a novel methodology for the investigation of socioeconomic disparities in health. By using multilevel analysis to model health inequalities within and between strata defined by the intersection of multiple social and demographic dimensions, the authors provide

Objectives: Lucilia sericata maggots are successfully used for treating chronic wounds. As the healing process in these wounds is complicated by bacteria, particularly when residing in biofilms that protect them from antibiotics and the immune system, we assessed the effects of maggot excretions/secretions (ES) on Staphylococcus aureus and Pseudomonas aeruginosa biofilms, the clinically most relev

We present measurements of the elliptic flow (v2) as a function of transverse momentum (pT), pseudorapidity (η), and centrality in d+Au collisions at sNN=200, 62.4, 39, and 19.6 GeV. The beam-energy scan of d+Au collisions provides a testing ground for the onset of flow signatures in small collision systems. We measure a nonzero v2 signal at all four collision energies, which, at midrapidity and l

Presentation

‘Sustainability’, often presented through an ecological–economic–social triad, is today one of spatial planning’s absolute key concepts (and key priorities). But it is also a highly contested concept, whose meaning is often considered evasive or vague. In this paper, we try to counterweigh such evasiveness by putting emphasis on the material landscape produced within a project that is frequently d

The transcription factor ZNF224 plays a key proapoptotic role in chronic myelogenous leukemia (CML), by modulating Wilms Tumor protein 1 (WT1) dependent apoptotic genes transcription. Recently, we demonstrated that Bcr-Abl signaling represses ZNF224 expression in Bcr-Abl positive CML cell lines and in CML patients. Interestingly, Imatinib and second-generation tyrosine kinase inhibitors specifical

Visceral leishmaniasis (VL) is a vector-borne disease, highly influenced by environmental factors, which is an increasing public health problem in Iran, especially in the north-western part of the country. A geographical information system was used to extract data and map environmental variables for all villages in the districts of Kalaybar and Ahar in the province of East Azerbaijan. An attempt t

The prospects of domestic punishment might compel leaders responsible for the initiation of the war to continue fighting until they achieve favorable war outcomes (Croco 2011, 2015). As applied to war duration, this logic implies that ‘culpable’ leaders do not have incentives to end a war that will bring defeat. This paper argues that leaders can escape this dilemma by blaming and replacing their

Historian David Lowenthal (1985) has pointed out the past is often perceived and represented as “a foreign country” in which cultural heritage is implicitly understood to be bound to geographical territories and associated notions of what it implies to have roots, an identity, and a place in which to belong. This is the paradigmatic background against which so many heritage museums have been found

Gene-panel sequencing allows comprehensive analysis of multiple genes simultaneously and is now routinely used in clinical mutation testing of high-risk breast and ovarian cancer patients. However, only BRCA1 and BRCA2 are often analyzed also for large genomic changes. Here, we have analyzed 10 clinically relevant susceptibility genes in 95 breast or ovarian cancer patients with gene-panel sequenc