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Genome-wide association studies have linked lung cancer risk with a region of chromosome 15q25.1 containing CHRNA3, CHRNA5 and CHRNB4 encoding α3, α5 and β4 subunits of nicotinic acetylcholine receptors (nAChR), respectively. One of the strongest associations was observed for a non-silent single-nucleotide polymorphism at codon 398 in CHRNA5. Here, we have used pharmacological (antagonists) or gen
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Aim: To describe initiation and extent of parents' application of skin-to-skin care (SSC) with their preterm infants at two Swedish neonatal intensive care units. Methods: The duration of SSC was recorded in 104 infants' medical charts during their hospital stay, and the parents answered a questionnaire. Results: Both parents were involved in the practice of SSC. Three infants experienced SSC dire
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Kangaroo Mother Care (KMC) supports parents' role at the neonatal intensive care unit (NICU). To enhance parents' provision of KMC, it is essential to obtain knowledge of what parents perceive as supportive factors and barriers regarding their opportunities to perform KMC. Aim: To identify factors that parents of preterm infants perceived as supportive factors or barriers for their performance of
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Objective: intimate partner violence is a significant health problem. Fear of retaliation and shame may prevent women from telling anyone about the violence. This study investigated the prevalence of disclosure and police reporting of intimate partner violence during the first year postpartum. Design: a prospective longitudinal Swedish cohort study based on information from 2563 women who answered
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In this study, steady-state laminar natural convection of Cu and TiO2 nanofluids inside different enclosures is numerically investigated. Natural convection is concerned due to a temperature difference between the hot and cold surfaces. The Boussinesq approximation is used to form the governing equations and the commercial software package ANSYS Fluent version 14.0 is used to numerically solve the
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This article compares what homeowners identified as motives and barriers for installing photovoltaic panels in Sweden in 2008–2009 and in 2014–2016. Earlier research has provided snapshots of existing barriers and motives, but not analyzed changes over time, as is done here. Between 2008 and 2014, the PV market in Sweden changed profoundly, with the introduction of subsidies and changes in rules,
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Objective Low physical fitness and obesity have been associated with higher risk of developing heart failure (HF), but their interactive effects are unknown. Elucidation of interactions among these common modifiable factors may help facilitate more effective primary prevention. Methods We conducted a national cohort study to examine the interactive effects of aerobic fitness, muscular strength and
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From exploratory studies and theoretical expectations it is known that simplifying approximations in spectroscopic analysis (local thermodynamic equilibrium (LTE), 1D) lead to systematic biases of stellar parameters and abundances. These biases depend strongly on surface gravity, temperature and, in particular, for LTE versus non-LTE (NLTE), on metallicity of the stars. Here we analyze the [Mg/Fe]
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Using Swedish firm-level data on all firms and their affiliates abroad, we investigate what observable firm and country characteristics affect the size of an affiliate in a particular destination. We employ the richness of the data to investigate the importance of destination country factors in explaining firm outward FDI activities and distinguish between the factors that affect such activities i
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It has recently been found that anti-Stokes photoluminescence can be observed in degenerately n-doped indium phosphide nanowires, when exciting directly into the electron gas. This anti-Stokes mechanism has not been observed before and allows the study of carrier relaxation and recombination using standard photoluminescence techniques. It is important to know if this anti-Stokes photoluminescence
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The present study investigated the relationship between linguistic tone processing and cortical thickness of bilateral planum temporale (PT) and pars opercularis of the inferior frontal gyrus (IFGpo). Swedish tones on word stems function as cues to upcoming endings. Correlating structural brain imaging data with participants’ response time patterns for suffixes, we found that thicker cortex in the
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Nitrogen molecules in ambient air exposed to an intense near-infrared femtosecond laser pulse give rise to cavity-free superradiant emission at 391.4 and 427.8 nm. An unexpected pulse duration-dependent cyclic variation of the superradiance intensity is observed when the central wavelength of the femtosecond pump laser pulse is finely tuned between 780 and 820 nm, and no signal occurs at the reson
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4′-Octyl-4-biphenylcarboxylic acid (1g, AC-55649) was identified as a highly isoform-selective agonist at the human RARβ2 receptor in a functional intact cell-based screening assay. The subsequent hit to lead optimization transformed the lipophilic, poorly soluble hit into a more potent and orally available compound (2, AC-261066) with retained β2 selectivity and greatly improved physiochemical pr
