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From giant clumps to clouds – I. The impact of gas fraction evolution on the stability of galactic discs

The morphology of gas-rich disc galaxies at redshift ∼ 1–3 is dominated by a few massive clumps. The process of formation or assembly of these clumps and their relation to molecular clouds in contemporary spiral galaxies are still unknown. Using simulations of isolated disc galaxies, we study how the structure of the interstellar medium and the stability regime of the discs change when varying the

On the steady-state workpiece flow mechanism and force prediction considering piled-up effect and dead metal zone formation

The manufacturing of miniaturized components is indispensable in modern industries, where the uncut chip thickness (UCT) inevitably falls into a comparable magnitude with the tool edge radius. Under such circumstances, the ploughing phenomenon between workpiece and tool becomes predominant, followed by the notable formation of dead metal zone (DMZ) and piled-up chip. Although extensive models have

Exposure to artificial light at night alters innate immune response in wild great tit nestlings

The large-scale impact of urbanization on wildlife is rather well documented; however, the mechanisms underlying the effects of urban environments on animal physiology and behaviour are still poorly understood. Here, we focused on one major urban pollutant – artificial light at night (ALAN) – and its effects on the capacity to mount an innate immune response in wild great tit (Parus major) nestlin

Identification and characterization of the CCoAOMT gene family in apple, Chinese white pear, and peach

Lignin is one of the main components of plant cell walls, which provides mechanical support for plants and also contributes to resisting against plant pathogenic fungi. In the fruit industry, the lignin content can affect the quality of fruit. The biosynthesis of lignin involves a variety of enzymes, of which caffeoyl-CoA 3-O-methyltransferase (CCoAOMT) is a class of methyltransferases that plays

Neutrophil extracellular traps in colorectal cancer progression and metastasis

Neutrophils form sticky web-like structures known as neutrophil extracellular traps (NETs) as part of innate immune response. NETs are decondensed extracellular chromatin filaments comprising nuclear and cytoplasmic proteins. NETs have been implicated in many gastrointestinal diseases including colorectal cancer (CRC). However, the regulatory mechanisms of NET formation and potential pharmacologic

Managing multiple risks in land use planning – a literature review

Many risks addressed in land use planning, such as flooding and accidents involving hazardous materials, have widely different characteristics which makes them difficult to compare. Yet, these risks sometimes need to be considered together in order to support decision-making. Furthermore, risks can sometimes affect each other, which differentiate the land use planning context from situations where

Occupational balance and satisfaction with daily occupations in persons with depression or anxiety disorders

Introduction: Occupational balance and satisfaction with daily occupations are two central concepts in occupational science. The aim of the present study was therefore to explore associations between different aspects of occupational balance and satisfaction with daily occupations. A second aim was to explore whether different aspects of occupational balance predicted satisfaction with daily occup

Three-dimensional coherent x-ray diffraction imaging of ferroelastic domains in single CsPbBr3 perovskite nanoparticles

Metal halide perovskites attract significant interest due to their remarkable performance in optoelectronic devices. However, the gap in understanding the relationship between their nanoscale structure and properties limits their application towards novel devices. In this work, twinned ferroelastic domains in single 500 nm CsPbBr3 particles are studied with 3D Bragg coherent x-ray diffraction imag

The management of women with ductal carcinoma in situ of the breast in Australia and New Zealand between 2007 and 2016

Background: The incidence of detected ductal carcinoma in situ (DCIS) continues to increase and now accounts for 14% of all breast cancer, and 20%–25% of screen-detected cases. Treatment trends of DCIS are important in order to inform the ongoing debate about possible overdiagnosis and overtreatment, but have not been investigated for over a decade in Australia and New Zealand. Against this backgr

Why are our political rivals so blind to the problems facing society? Evidence that political leftists and rightists in Israel mentally construe collective threats differently.

The present research examines the hypothesis that political leftists and rightists mentally construe collective threats differently, such that each political side views the threats that are meaningful to them as close and concrete, whereas other threats are underemphasized and perceived as distant and abstract. In two studies (total N = 796) we show that Israeli-Jewish political leftists perceive

Long- and short-run components of factor betas : Implications for stock pricing

We propose a new model that estimates the long- and short-run components of the variances and covariances. The advantage of our model to the existing DCC-based models is that it uses the same form for both the variances and covariances and estimates these moments simultaneously. We apply this model to obtain long- and short-run factor betas for industry test portfolios. We find that the risk premi

Incidence of tuberculosis and early mortality in a large cohort of HIV infected patients receiving antiretroviral therapy in a tertiary hospital in Addis Ababa, Ethiopia

Preceding studies on morbidities and mortalities associated with TB in a cohort of HIV care indicate high incidence of TB development and premature death among patients on highly active antiretroviral treatment (HAART). This study aims to measure the rate of TB, TB mortality, and associated risk factors following commencement of HAART in a cohort of patients attending HIV care in Ethiopia. Patient

A thermodynamically consistent modelling framework for strongly time-dependent bainitic phase transitions

In this work, a thermodynamically consistent constitutive framework is introduced that is capable of reproducing the significant time-dependent behaviour of austenite-to-bainite phase transformations. In particular, the aim is to incorporate the effect of these diffusion-controlled processes by plasticity-like evolution equations instead of incorporating related global diffusion equations. To this

Justifying interventions-The case of ECOWAS in Liberia

In contrast to the other chapters in Part V, Nina Wilén’s focus is on multilateral military interventions at the regional level: She explores the relationship between sovereignty, intervention, and the international normative order, by examining how ECOWAS, an African regional organization, justified its intervention in Liberia’s civil war referring to international norms. Based on a critical disc

The Intermediality of Performance

This chapter looks at how different kinds of bodies and objects interact in a performance and at how the presence and emergence of an event interact with mediation and transmediation. Our intermedial approach allows us to explore the entanglement of presence and representation, of performance and media products, of performativity and intermediality. Through a combination of the perspectives of per

Sustainable and Resilient Land Use Planning : A Multi-Objective Optimization Approach

Land use allocation (LUA) is of prime importance for the development of urban sustainability and resilience. Since the process of planning and managing land use requires balancing different conflicting social, economic, and environmental factors, it has become a complex and significant issue in urban planning worldwide. LUA is usually regarded as a spatial multi-objective optimization (MOO) proble

Fine tuning of the innate and adaptive immune responses by Interleukin-2

Novel immunotherapies for cancer and other diseases aim to trigger the immune system to produce durable responses, while overcoming the immunosuppression that may contribute to disease severity, and in parallel considering immunosafety aspects. Interleukin-2 (IL-2) was one of the first cytokines that the FDA approved as a cancer-targeting immunotherapy. However, in the past years, IL-2 immunothera

Clarifying the relationship between physical injuries and risk for suicide attempt in a Swedish national sample

Introduction: The Interpersonal-Psychological Theory of Suicide proposes that capability for suicide is acquired through exposure to painful and provocative events (PPEs). Although there is robust evidence for a positive association between aggregate measures of PPEs and risk for suicidal behavior, little is known about the contributions of physical injuries. The present study investigated the rel

An income-distributional analysis of the rent control subsidy

Rent control measures are typically in place to assist low-income households and decrease segregation. Yet, there is little empirical research on the social impact of such policies and specifically the role of how rent-controlled apartments are allocated. This study analyzes the income-distributional effects of rent control with a novel dataset that includes characteristics of those who received r

The Role of Global Actors in Sustainability Transitions – Tracing the Emergence of a Novel Infrastructure Paradigm in the Sanitation Sector

The literature on sustainability transitions increasingly recognizes that sectoral structures transcending national boundaries can both hinder and promote sustainability transitions. Yet there is only limited evidence on the roles of global actors in transforming entrenched socio-technical structures directly at the global scale. To explore the mechanisms of agency at the global scale, we develop