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Digital Transformations of Illicit Drug Markets: Reconfiguration and Continuity is authored by leading experts in the field of illicit drug sourcing, who draw on their interdisciplinary backgrounds to illustrate how modern technologies are embedded within our social structures. Since the digital (r)evolution, the sourcing of illicit drugs now takes place through smartphones, encryption, social med

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Diffusion magnetic resonance imaging (dMRI) is an important technique used in neuroimaging. It features a relatively low signal-to-noise ratio (SNR) which poses a challenge, especially at stronger diffusion weighting. A common solution to the resulting poor precision is to average signal from multiple identical measurements. Indeed, averaging the magnitude signal is sufficient if the noise is samp

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Objective: To determine whether a gout polygenic risk score (PRS) is associated with age at gout onset and tophaceous disease in European, East Polynesian, and West Polynesian men and women with gout. Methods: A 19-variant gout PRS was produced in 7 European gout cohorts (N = 4,016), 2 East Polynesian gout cohorts (N = 682), and 1 West Polynesian gout cohort (N = 490). Sex-stratified regression mo

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The operation of a froth flotation column can be described by a nonlinear convection–diffusion partial differential equation that incorporates the solids–flux and drift–flux theories as well as a model of foam drainage. The resulting model predicts the bubble and (gangue) particle volume fractions as functions of height and time. The steady-state (time-independent) version of the model defines so-

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We study the long-time behavior of solutions to quasilinear doubly degenerate parabolic problems of fourth order. The equations model, for instance, the dynamic behavior of a non-Newtonian thin-film flow on a flat impermeable bottom and with zero contact angle. We consider a shear-rate dependent fluid the rheology of which is described by a constitutive power law or Ellis law for the fluid viscosi

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Purpose: To evaluate the neurophenomenology of automatic writing (AW) in a spontaneous automatic writer (NN) and four high hypnotizables (HH). Methods: During fMRI, NN and the HH were cued to perform sponta- neous (NN) or induced (HH) AW, and a comparison task of copying complex symbols, and to rate their expe- rience of control and agency. Results: Compared to copying, for all participants AW was

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Academic research increasingly focuses on environmental sustainability as a specific societal mission to be addressed. However, the effects of the increasing sustainability orientation on output generation in public research organizations are largely unexplored. In this paper, we analyse the effects of the increasing importance of sustainability-oriented research topics on research and teaching ef

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The various structural components of the cortical degeneration of Alzheimer's disease were defined and graded. The severity of the degenerative process was thus mapped in different cortical areas where neuronal numbers and cortical width were also measured and compared with controls. Contrary to the general opinion that the degenerative process is rather uniformly diffuse, though accentuated in th

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Abstract Aim: The aim of this study was to investigate whether adolescents born extremely preterm differ from full-term born regarding mental health, social support and attachment style. Methods: Fifty-one young adults, born before the 29(th) gestational week and 54 born at term were investigated by self-reports. Psychological health was measured by the Beck Youth Inventories of Emotional and Soci

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Popular Abstract in Swedish Trots utvecklingen inom materialvetenskap, datorkapacitet och byggnadsteknik, fortsätter fel relaterade till byggnadsfysik att inträffa i våra byggnader. Dessa byggnadsfel spänner mellan att byggnader inte möter kraven på energianvändning till att byggnader orsakar hälsoproblem hos de människor som vistas i byggnaden till följd av att de utsätts för kemikalier eller bioDespite advances in material science, computers and building technology, building failures related to building physics continue to occur. These failures range from a building not meeting its energy use target to a building causing people to become ill from exposure to various chemicals or biological organisms. These failures cost society considerable amounts of money each year and many of these fa

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Objectives To validate the two recently developed disease activity indexes for assessment of primary Sjogren's syndrome (SS): the European League Against Rheumatism (EULAR) SS Patient Reported Index (ESSPRI) and the EULAR SS Disease Activity Index (ESSDAI). Methods A prospective international 6-month duration validation study was conducted in 15 countries. At each visit, physicians completed ESSDA

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We present an existence and stability theory for gravity-capillary solitary waves with constant vorticity on the surface of a body of water of finite depth. Exploiting a rotational version of the classical variational principle, we prove the existence of a minimizer of the wave energy H subject to the constraint I = 2 mu, where I is the wave momentum and 0 < mu << 1. Since H and I are both conserv

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The objective of this report is to provide an implementation guide to understanding the Energy Efficiency in Buildings (EEB) model as applied to the Swedish Residential sector. The report depicts the work that prepares the ground to use and test the model to evaluate energy efficiency policy instruments targeting the Swedish residential sector during the next phase of the project. It is argued wil

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Knowledge of interrater reliability in the evaluation of perfusion computed tomography (CTP) studies is very limited even though the method is widely used in the workup of acute stroke. The aims of this study were to estimate the inter- and intraolbserver agreement in the evaluation of CTP data and to evaluate the feasibility of the method. The CTP data of 20 consecutive patients (50% were females

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Regulations regarding impact and airborne sound insulation for lightweight timber constructions have become increasingly stringent due in particular to complaints by inhabitants. Accordingly, some building techniques frequently use elastomers at junctions so as to reduce low frequency noise. Development of accurate predictive tools (involving exact material properties) by using numerical methods s

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Using infrared reflection spectroscopy the authors show that the phase transitions from disordered high temperature Β- Zn4 Sb3 into the increasingly higher ordered and complex structured low-temperature phases α and α′ are accompanied by a significant increase in the free charge carrier density and a concomitant increase of the effective scattering rate.

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Single crystals of Nd0.6Gd0.4Se1.85 have been prepared by chemical transport reactions starting from pre-annealed powder samples. Satellite reflections observed in X-ray and electron diffraction experiments indicate the presence of a two-dimensional lattice distortion. The origin of this is a site occupancy wave and, coupled to this, a charge density wave in the planar selenium layer of this compo

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Transposable elements (TEs) are dynamically expressed at high levels in multiple human tissues, but the function of TE-derived transcripts remains largely unknown. In this study, we identify numerous TE-derived microRNAs (miRNAs) by conducting Argonaute2 RNA immunoprecipitation followed by small RNA sequencing (AGO2 RIP-seq) on human brain tissue. Many of these miRNAs originated from LINE-2 (L2) e