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Background: No targeted drugs are currently available against small cell lung cancer (SCLC). BCL-2 family members are involved in apoptosis regulation and represent therapeutic targets in many malignancies. Methods: Expression of BCL-2 family members in 27 SCLC cell lines representing all known four SCLC molecular subtypes was assessed by qPCR, Western blot and mass spectrometry-based proteomics.
Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are closely related diseases associated with smoking history and dysregulated immune response. However, not all smokers develop the disease, indicating that genetic susceptibility could be important. Therefore, the aim of this study was to search for the potential overlapping genetic biomarkers, with a focus on single nucleotide pol
Previous reports showed that nontypeable Haemophilus influenzae (NTHi) reside in macrophage-like cells in human adenoid tissue. This study investigated the ability of nonopsonized NTHi and encapsulated H. influenzae type b (Hib) to enter human monocytic and epithelial cells. The number of intracellular bacteria was determined by a viability assay and flow cytometry. To characterize the mechanisms
We have imaged the emissions from excitons and free charges in a methylammonium lead bromide perovskite (MAPbBr3) crystal. In a direct band gap semiconductor, dynamics of excited electrons and holes in hybrid lead-halide perovskites is rather complex because of the formation of excitons and the presence of traps and structural inhomogeneities. A recent report by Nah et al. (Nah, S.; Spokoyny, B.;
Objectives: We conducted a large cohort study to investigate the association between work-related wrist movements and carpal tunnel syndrome (CTS). Methods: Electro-goniometric measurements of wrist movements were performed for 30 jobs (eg, office work, child care, laundry work and slaughterhouse work). We measured wrist angular velocity, mean power frequency (MPF) and range of motion (ROM). We es
Aim: To evaluate the impact of initial mono- versus multitherapy on the ocular surface and related quality of life after 5 years follow-up in the Glaucoma Intensive Treatment Study (GITS). Method: The study included patients with primary open-angle glaucoma and pseudoexfoliation glaucoma who completed 5-year follow-up in GITS. Assessment of ocular surface disease (OSD) symptoms was done using a Sw
This study investigates whether a genderless second language (L2; English) reshapes grammatical gender (GG) effects derived from two gendered first languages (L1s; Ukrainian and Russian) in multilinguals. Previous work showed that when GG aligns across these L1s, it influences categorisation and recall of multilinguals, whereas mismatching L1s yield effects from the more proficient L1 only on cate
As gene therapy for haemophilia is now licensed in Europe, and the hub and spoke approach is widely promoted for its delivery and follow-up, it is essential that people with haemophilia (PwH) who are eligible and opt to have this treatment are enabled to obtain the maximum benefit. Ensuring the pathway that makes up the patient gene therapy journey is effective is key to achieving this. EAHAD and
OBJECTIVES: Most patients with pancreatic cancer who have undergone surgical resection eventually develop disease recurrence. This study aimed to investigate whether there is evidence to support routine surveillance after pancreatic cancer surgery, with a secondary aim of analyzing the implementation of surveillance strategies in the Nordic countries.MATERIALS AND METHODS: A scoping review was co
Allt om bröllop är en av Sveriges största bröllopstidningar vari läsaren förväntas inspireras till sin kommande bröllopsdag, bland annat genom att se andra läsares bröllopsfotografier. Syftet med den här studien är att med Allt om bröllop som fall granska vad bröllopsfotografier kan säga om det nutida bröllopet samt vad bröllopsfotografens uppdrag egentligen är. Genom att utföra en komparativ visu
The High Arctic Large Igneous Province (HALIP) formed in the circum-Arctic during the Cretaceous. The timing and duration of emplacement of these mafic magmas are important for understanding the climatic and environmental effects, yet many uncertainties remain. The dating methods used vary greatly between different regions. For example, the mafic intrusions in Svalbard have mainly been dated using
Extrapolation in Time in Thermal Fluid Structure Interaction Philipp Birken, Tobias Gleim, Detlef Kuhl and Andreas Meister Abstract We consider time dependent thermal fluid structure interaction. The re- spective models are the compressible Navier-Stokes equations and the nonlinear heat equation. A partitioned coupling approach via a Dirichlet-Neumann method and a fixed point iteration is employed
https://www.maths.lu.se/fileadmin/maths/personal_staff/Philipp_Birken/BirkenGleimKuhlMeisterCE14.pdf - 2026-07-21
Olika socialgrupper drabbas olika av artros och sjukskrivning – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Olika socialgrupper drabbas olika av artros och sjukskrivning 2012-04-19 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. En tred
https://www.vetenskaphalsa.se/olika-socialgrupper-drabbas-olika-av-artros-och-sjukskrivning/ - 2026-07-21
Orsaker till tumörsjukdomen hibernom klarlagda – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Orsaker till tumörsjukdomen hibernom klarlagda 2011-01-03 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Skador på kromosom 11 vid hibernom. B
https://www.vetenskaphalsa.se/orsaker-till-tumorsjukdomen-hibernom-klarlagda/ - 2026-07-21
Sarkom – vilka provtagningsmetoder fungerar bäst? – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Sarkom – vilka provtagningsmetoder fungerar bäst? 2016-02-03 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Sarkom är ett gemensamt namn fö
https://www.vetenskaphalsa.se/sarkom-vilka-provtagningsmetoder-fungerar-bast/ - 2026-07-21
Membrane fouling, particularly by soft, deformable particles, is a significant challenge in microfiltration (MF) processes, leading to reduced efficiency and increased operational costs. This thesis investigates the formation of filter cake layers by numerically simulating fluid flow through microfluidic membranes designed with random, non-overlapping cylindrical micropillar arrays. The study aims
