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Purpose: The Workplace Dialogue is a digitalized method directed at managers. The purpose of this study was to explore managers’ experiences of using the digital Workplace Dialogue in cases of employee ill-health. Design/methodology/approach: The Workplace Dialogue provides an easy and accessible method for managers, including text, short films, client examples and concrete guides that provides su
Cubosomes are self-assembled lipid nanoparticles with a unique structure that hold significant promise for drug delivery. Cubosomes can encapsulate and transport a wide range of pharmaceuticals and imaging agents, potentially enhancing targeted therapies and medical imaging applications. Although there is growing interest in using cubosomes as drug delivery vehicles, their interactions with biolog
BACKGROUND: Dapagliflozin improved cardiometabolic outcomes following myocardial infarction in patients without prior type-2 diabetes (T2DM) in the DAPA-MI (dapagliflozin in patients with myocardial infarction) trial. The effect of glycemic status and body mass index (BMI) post–myocardial infarction requires elucidation. METHODS: Participants with T2DM diagnosis, without baseline hemoglobin A1c, o
As the impact of climate change intensifies, there is an urge to adapt Swedish residential buildings with a special focus on improving their energy efficiency and resilience. In this study, adaptive strategies through Artificial Intelligence and Reinforcement Learning will be provided for the energy management of different Swedish residential buildings. The aim will be the optimization of energy u
In order for any learning-based model to be considered reliable, it needs a well-behaved uncertainty or confidence estimate. Most modern neural networks do produce a confidence estimate in the form of their softmax output probability. However, the softmax probability is invalid for out-of-distribution data. Gaussian processes are known to produce a well-behaved confidence estimate that is aware of
Introduction: Strengthening Primary Health Care (PHC) is essential for building resilient and equitable health systems, but PHC faces barriers in implementation, resource allocation, and political prioritisation. This study aimed to develop a strategic roadmap to enhance PHC by identifying core values, priorities, and actionable strategies through expert consensus. Methods: A two-round Delphi stud
Objective Type I interferons (IFN) drive systemic lupus erythematosus (SLE) pathogenesis. Some patients develop neutralizing IFN autoantibodies (anti-IFN ab), which theoretically could modify disease activity. We aimed to determine the prevalence of anti-IFN ab in patients with SLE, identify the age and when during the disease course of anti-IFN ab emerge, and assess their association with organ d
Under electrochemical polarization, many electrocatalysts can undergo oxidation that alters their reactivity and can lead to restructuring and dissolution. In this context, the structure-property relationships of electrocatalysts, as well as their kinetics and dynamic behaviour, are still poorly understood. This knowledge gap mainly relies on the limitations of many traditional spectroscopic and s
We present results of Population III (Pop III) formation in the megatron suite of simulations, which self-consistently follows radiation and non-equilibrium chemistry, and resolves gas at near-pc resolution in a Milky Way-mass progenitor at Cosmic Dawn. While the very first Pop III stars form in haloes with masses well below the atomic cooling limit, the majority of Pop III stars form in more mass
Objectives: – To evaluate the prevalence of mood disorder symptoms and measure the quality of life in women with vulvar dermatoses attending a specialized vulvar clinic in southern Sweden. Materials and Methods: – A questionnaire-based study among consecutive women attending the vulvar unit at the Department of Dermatology and Venereology at Skåne University Hospital. Sociodemographic factors were
Background: The variable clinical outcomes of mesenchymal stromal cell (MSC)-based therapy in acute respiratory distress syndrome (ARDS) are attributed to a variety of factors, including host microenvironmental factors. Interleukin-1β (IL-1β) has been linked to the development and progression of ARDS, and we have previously found that IL-1β could be used to predict MSC activation in vitro. However
Standardized Care Pathway (SCP) for patients presenting with macroscopic haematuria was introduced in Sweden in 2015. In contrast to neighbouring countries, the Swedish model includes all patients with macroscopic haematuria above the age of 50, notwithstanding obvious causes. The aim of this study was to characterize the patients referred within the SCP and the presence of acute cystitis.All pati
Postural orthostatic tachycardia syndrome (POTS) as conventionally defined is a chronic condition (typically >3 months duration) incorporating reproducible symptoms of orthostatic intolerance (including dizziness/lightheadedness, and near-syncope) in the absence of orthostatic hypotension (i.e., absence of a sustained systolic blood pressure drop >20mmHg with upright posture). 1-10 More recently
Populärvetenskaplig sammanfattning: Naturbetesmarkerna minskade med 86,7% från 1927 till 1990. Denna minskning är alarmerande eftersom många idag hotade och sällsynta arter är beroende av dessa. En stor del av anledningen till detta är att staten ända in på 1980-talet i sin rådgivning danade för att dessa marker antingen skulle bearbetas med konstgödsel och ogräsbekämpning eller planteras med trädThe rural landscape of Sweden has changed rapidly during the 20:th century. Measurements from 1927 compared to those from 1990 show that the area of non managed pasture in Sweden has declined by 86.7 %. Since a lot of threatened and rare species are dependent of this kind of land, these figures are alarming. During the last 30-40 years non managed pasture has declined due to abandonment, tree plan
Populärvetenskaplig sammanfattning: Målet med studien är att se vilka samband som finns mellan insamlad fältdata och beräknad satellitdata för bokskogsbestånd i södra Sverige (Häckeberga naturreservat och naturområde). Fältdata som använts består av uppskattat bladyteindex, beräknad biomassa samt kategoriserade åldersgrupper av 19 provytor bokskog (Fagus Sylvatica), indelat i tre grupper. ProvytorThe aim of this investigation is to study the relationship between leaf area index, biomass and satellite reflectance data of some beech forests (Fagus Sylvatica) in southern Sweden (Häckeberga nature reserve). In 19 forest stands, measurements of tree structural parameters like tree height and tree diameter at breast height were performed. In addition, the leaf area index was estimated optically
Introduction: Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. Therefore, the aim was to examine the associations of health-related quality of life (HRQoL) and lifestyle habits with chronic pain at a two-year follow-up in individuals with knee pain. Methods:
