Filtyp
Background: Emerging data propose biomarker alteration due to clonal selection between the primary invasive breast cancer and corresponding metastases. In addition, impact on survival has been demonstrated. The present study investigates the relationship between the oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) between primary ductal carcin
Elevated moisture contents due to exposed weather conditions and ageing façade materials can often lead to degradation and increased risks for the building walls, but also affect the insulating properties of the materials, as thermal and hygric behaviour of building materials are closely interconnected. This paper presents the first results from a study of a 1950-ies multi-family building with a p
Trees growing at their altitudinal or latitudinal distribution in Fennoscandia have been widelyused to reconstruct warm season temperatures, and the region hosts some of the world’slongest tree-ring chronologies. These multi-millennial long chronologies have mainly beenbuilt from tree remains found in lakes (subfossil wood from lake-shore trees). We used aunique dataset of Scots pine tree-ring dat
Context: The diagnosis of late-onset hypogonadism (LOH) in older men with age-related declines in testosterone (T) is currently not well characterized. Objective: Our objective was to investigate whether different forms of hypogonadism can be distinguished among aging men. Design: The study was a cross-sectional survey on 3369 community-dwelling men aged 40-79 yr in eight European centers. Methods
Aims: This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or CRS without nasal polyps (CRS-NP), in a prospective multi-centre study. Methodology: Two hundred and seven patients with RARS, CRS+NP or CRS-
Biotic and abiotic elicitors induce biosynthesis of secondary metabolites (phytoalexins) as a defense against pathogenic organisms in plants. The use of cell suspension cultures in combination with elicitors offer excellent experimental model systems for studies on various elicitor-induced responses of plant tissues. Various elicitors were added to cell suspension culture of Eschscholtzia californ
Modern medical implants are of increasing complexity and with that, the need for fast and flexible communication with them grows. A wireless system is preferable and an inductive link is the most commonly used. But it has the drawback of a very short range, essentially limited to having the external transceiver touching the patient. The Medical Implant Communication System, MICS, is a standard aim
Objective In this study we aimed to estimate the effect of diabetes, educational level and income on the risk of mortality and cardiovascular events in primary care patients with hypertension. Methods We followed 62,557 individuals with hypertension diagnosed 2001-2008, in the Swedish Primary Care Cardiovascular Database. Study outcomes were death, myocardial infarction, and ischemic stroke, asses
BACKGROUND: Next of kin participation in care is a cornerstone of palliative care and is thus important in nursing homes, and outcomes following interventions need to be evaluated using robust methods.OBJECTIVE: To use within-group and within-individual analytical approaches to evaluate the participation of next of kin in care following an intervention and to compare the outcome between the interv
A series of iron(IV) oxo complexes, which differ in the donor (CH2py or CH2COO-) cis to the oxo group, three with hemilabile pendant donor/second coordination sphere base/acid arms (pyH/py or ROH), have been prepared in water at pH 2 and 7. The νFe=O values of 832 ± 2 cm-1 indicate similar FeIV=O bond strengths; however, different reactivities toward C-H substrates in water are observed. HAT occur
Purpose: Personalized therapies are leading to an increasing number of marketing authorizations based on single-arm trials, which increases the demand for better post-authorization monitoring strategies. The aim of the present study was to estimate the power over time as data accrue in population-based registries for detecting deviations from the expected efficacy/safety of chimeric antigen recept
