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Pancreas-derived islet amyloid polypeptide (IAPP) aggregates and deposits in the pancreas and periphery of Type 2 Diabetes (T2D) patients, contributing to diabetic complications. The excess IAPP can be removed by autoantibodies, and increased levels of immunoglobulin (Ig) G against IAPP have been reported in T2D patients. However, whether other Ig classes are also affected and if the levels can be
The purpose of this study is to identify potential factors impacting the internationalization process of a small- or medium sized fashion company. We aim to shed light on potential key factors that can provide an understanding of a successful internationalization process and illustrate our findings in a model applicable to firms with similar characteristics. The study is conducted through a qualit
This thesis examines whether the transfer of a company containing accumulated retained earnings to a shareholder benefiting from a more favourable dividend tax regime can constitute a form of structural dividend stripping under EU law. Unlike traditional dividend stripping arrangements, such as cum-ex and cum-cum transactions, these structures rely on intra-group corporate restructurings through w
BACKGROUND: Due to increasing older populations worldwide, injuries, disabilities and deaths caused by falls among the elderly represent a growing human and societal problem. We aimed to improve health among men of at least 70 years of age with low-normal to low testosterone and mobility problems by using testosterone undecanoate (TU) injections, progressive strength training, and oral supplements
The aim was to describe hematopoietic stem cell (HSC) donors' experiences focusing on information and side effects during the first year after donation. Our prospective Swedish cohort study with adult HSC donors was performed from 2019 to 2022, with questionnaires at four time points from before until 12 months after donation. 173 unrelated and 68 related donors participated, and the majority dona
In the effort to obtain a precise measurement of leptonic CP-violation with the ESSνSB experiment, accurate and fast reconstruction of detector events plays a pivotal role. In this work, we examine the possibility of replacing the currently proposed likelihood-based reconstruction method with an approach based on Graph Neural Networks (GNNs). As the likelihood-based reconstruction method is reason
National hydrogen strategies are emerging as a critical pillar of climate change policy. For homes connected to the gas grid, hydrogen may offer an alternative decarbonisation pathway to electrification. Hydrogen production pathways in countries such as the UK will involve both the gas network and the electricity grid, with related policy choices and investment decisions impacting the potential co
It is a well-established fact that the use of gestures is a ubiquitous feature of communication with language. This is true for both spoken and signed languages. However, while in spoken languages, gestures are produced in a different modality than speech (visual versus vocal/auditory, respectively), gestural elements in sign languages are produced in the same modality as sign (both are visual). T
Population growth and climate change have accelerated groundwater depletion globally. Interferometric synthetic aperture radar (InSAR) is a fairly new satellite remote sensing technique based on SAR images that offers a high-accuracy monitoring system of land surface motion driven by groundwater level changes in time and space that can never be achieved with point-in-situ measurements. In producti
Background and aims: Gallstone disease during pregnancy can have varying consequences, from mild to severe and even life-threatening. The aim was to investigate how gallstone intervention during pregnancy impacts pregnancy, delivery and the newborn child. Methods: Pregnant patients 18–45 years identified from the Swedish National Register for Gallstone Surgery and Endoscopic Retrograde Cholangiopa
Objective. In patients with axial spondyloarthritis (axSpA) initiating secukinumab (SEC), we aimed to identify baseline (treatment start) predictors of achieving low disease activity (LDA) after 6 months, as measured by the Axial Spondyloarthritis Disease Activity Score using C-reactive protein (ASDAS-CRP) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), as well as treatment contin
Much scholarship has critiqued the fact that non-governmental organisations (NGOs), as a result of global neoliberalism and consequential state retreat, have become private service providers of children’s protection rights. But how can we explain the situation when neoliberal states also undergo autocratisation and take back service provision from NGOs, while at the same time preserving the privat
Pediatric cancers exhibit complex evolutionary dynamics driven by genetic instability, clonal selection, epigenetic reprogramming, and microenvironmental interactions. Tumor evolution is typically characterized by branching phylogenies, where subclones with unique genetic profiles emerge at different locations and time points. Partly as a result of this diversity, advanced cancers often develop re
Small angle X-ray diffraction (SAXD), resonance Raman (RR) spectroscopy with 413 nm excitation, and non-resonance Raman technique with 785 nm excitation were used to probe the influence of entrapped cytochrome c (Cyt c) on the structure of hydrated phytantriol (Phyt) liquid-crystalline phases as well as conformational changes of heme group and secondary structure of the protein. SAXD measurements
Ahlgren AR, Cinthio M, Steen S, Nilsson T, Sjoberg T, Persson HW, Lindstrom K. Longitudinal displacement and intramural shear strain of the porcine carotid artery undergo profound changes in response to catecholamines. Am J Physiol Heart Circ Physiol 302: H1102-H1115, 2012. First published December 23, 2011; doi:10.1152/ajpheart.00470.2011.-The effects of catecholamines on longitudinal displacemen
OBJECTIVE: To evaluate compliance with screening and prevalence of abdominal aortic aneurysm (AAA) in relation to background data regarding area-based socioeconomic status. METHODS: Our department annually invites 4300 65-year-old men from the city of Malmö and 15 neighboring municipalities to ultrasound AAA screening. In a cross-sectional cohort study, compliance and AAA prevalence among 8269 men
Recent studies have shown that activation of the complement and contact systems results in the generation of antibacterial peptides. Streptococcus pyogenes, a major bacterial pathogen in humans, exists in more than one hundred different serotypes due to sequence variation in the surface-associated M protein. Cases of invasive and life-threatening S. pyogenes infections are commonly associated with
On 2 November 1994, the Human Rights Committee adopted General Comment No. 24 (52), which was clearly provoked by the great number of reservations deposited by States to the International Covenant on Civil and Political Rights (ICCPR) and its two Optional Protocols. In this decision, the Committee states its opinion on a variety of matters. All relate to the permissibility and effect of reservatio
Popular Abstract in Swedish Amerikanska krigare i Vietnam: Krigarvärderingar och myten om krigserfarenheten under Vietnamkriget, 1965-1973.In the Western world there has been a general consensus that in the aftermath of Auschwitz and Hiroshima, romanticized masculine images of war and soldiering have reached a turning point. This book challenges the view that the post- 1945 era has to a great extent been without romantizations of warriorhood. In the thesis I show that the American combat soldiers in Vietnam were not beyond the influe
