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Epidemiology and outcome of myeloma are mainly reported from large university centers and collaborative groups, and do not represent ‘real-world’ patients. The Swedish Myeloma Registry is a prospective population-based registry documenting characteristics, treatment and outcome in newly diagnosed myeloma, including asymptomatic and localized forms, with the purpose of improving disease management
The structures of Ruddlesden-Popper n = 2 member phases Sr3-xYxFe125Ni0.75O7-δ with 0 ≤ x ≤ 0.75 have been investigated using neutron powder diffraction and K-edge Fe and Ni EXAFS/XANES spectroscopy in order to gain information about the evolution of the oxygen vacancy distribution and Fe/Ni oxidation state with x. Both samples prepared at 1300°C under a flow of N2(g), with δ = 1.41-1.00, and samp
Background: Up-to-date epidemiological stroke studies are important for healthcare planning and evaluating prevention strategies. This population-based study investigates temporal trends in stroke incidence and case-fatality in southern Sweden. Methods: First-ever stroke cases in the local catchment area of Skåne University Hospital in Lund, Sweden, between March, 2015 and February, 2016, were inc
Recent conceptual studies identify gain, normative and hedonic factors as three categories of motivations of consumer proenvironmental behavior. However, empirical understanding of how these motivations interact and affect proenvironmental behavior is limited. This study is based on a survey of car owners in Sweden (N = 573) and uses structural equation modeling to analyze the data. The empirical
This study analysed demand for 12 metals in global climate mitigation scenarios up to 2060 and quantified the impacts on demand of different assumptions on improvements and technological mix. Annual and cumulative demands were compared with reserves and current mining rates. The study results showed that reserves are sufficient to support the total level of solar power, wind power and electric mot
Background. Disease severity and outcome in community-acquired pneumonia (CAP) depend on the host and on the challenge of the causal microorganism(s). We measured levels of immunoglobulins (Igs) and complement in 257 hospitalized adults with CAP and examined the association of low levels of Igs or complement to microbial etiology, disease severity, and short-term and long-term outcome. Methods. Se
Objectives Our aim was to use the opportunity provided by the European Scleroderma Observational Study to (1) identify and describe those patients with early diffuse cutaneous systemic sclerosis (dcSSc) with progressive skin thickness, and (2) derive prediction models for progression over 12 months, to inform future randomised controlled trials (RCTs). Methods The modified Rodnan skin score (mRSS)
This paper reports a detailed study of techniques for identifying boosted, hadronically decaying W bosons using 20.3 fb (Formula presented.) of proton–proton collision data collected by the ATLAS detector at the LHC at a centre-of-mass energy (Formula presented.). A range of techniques for optimising the signal jet mass resolution are combined with various jet substructure variables. The results o
A search for the associated production of the Higgs boson with a top quark pair (ttH) is reported. The search is performed in multilepton final states using a data set corresponding to an integrated luminosity of 36.1 fb-1 of proton-proton collision data recorded by the ATLAS experiment at a center-of-mass energy s=13 TeV at the Large Hadron Collider. Higgs boson decays to WW∗, ττ, and ZZ∗ are tar
Aims Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. The aims of this study were to determine the expression profile of 5HT receptors in murine MIN6 β-cells and to examine the effects of pharmacological activation of 5
Lignocellulosic biomass is a promising alternative fuel source which can promote energy security, reduce greenhouse gas emissions, and minimize fuel consumption when paired with advanced combustion strategies. Pyrolysis is used to convert lignocellulosic biomass into a complex mixture of phenolic-rich species that can be used in a transportation fuel. Anisole (or methoxybenzene) can be used as a s
Whether hydroxyapatite (HA) orientation in fossilised bone samples can be non-destructively retrieved and used to determine the arrangement of the bone matrix and the location of muscle attachments (entheses), is a question of high relevance to palaeontology, as it facilitates a detailed understanding of the (micro-)anatomy of extinct species with no damage to the precious fossil specimens. Here,
A numerical and experimental study on the devolatilization of a large biomass particle is carried out to quantify the effect of homogeneous volatile combustion on the conversion of the particle and on the temperature and species distribution at the particle vicinity. A global chemical kinetic mechanism and a detailed reaction mechanism are considered in a one dimensional numerical model that takes
Differences in the elemental abundances of planet-hosting stars in binary systems can give important clues and constraints about planet formation and evolution. In this study we performed a high-precision, differential elemental abundance analysis of a wide binary system, HD 80606/80607, based on high-resolution spectra with high signal-to-noise ratio obtained with Keck/HIRES. HD 80606 is known to
The Xga blood group is differentially expressed on erythrocytes from men and women. The underlying gene, PBDX, was identified in 1994, but the molecular background for Xga expression remains undefined. This gene, now designated XG, partly resides in pseudoautosomal region 1 and encodes a protein of unknown function from the X chromosome. By comparing calculated Xga allele frequencies in different
The Amazon Basin is a unique region to study atmospheric aerosols, given their relevance for the regional hydrological cycle and the large uncertainty of their sources. Multi-year datasets are crucial when contrasting periods of natural conditions and periods influenced by anthropogenic emissions. In the wet season, biogenic sources and processes prevail, and the Amazonian atmospheric composition
