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To apply and compare magnetic resonance imaging (MRI) metal artifact reducing sequences (MARS) including subtraction imaging after contrast application in patients with metal-on-metal (MoM) hip prostheses, investigate the prevalence and characteristics of periprosthetic abnormalities, as well as their relation with pain and risk factors.
In this study, a large, farm-based, co-digestion plant in southern Sweden, using manure and various food industry wastes is investigated concerning its use of energy and its emissions of greenhouse gases from a life cycle perspective based on measured, site-specific data. The biogas is upgraded and utilized as a vehicle fuel, distributed via the natural gas grid. The case-study also includes a nov
We present a prospective multicentre cohort of 20 children with acute lymphoblastic leukaemia (ALL) and cerebral sinus venous thrombosis (CSVT). The study covers a period of 5years and comprises 1038 children treated according to the Nordic Society of Paediatric Haematology and Oncology (NOPHO) ALL 2008 protocol. The cumulative incidence of CSVT was 2%. Sixteen of the thromboses were related to as
Resistivity measurements were carried out in order to identify preferential seepage paths in a small dam in central Sweden. Increased seepage flow had been observed at high reservoir levels. Repeated resistivity measurements were performed along the dam crest during 24 hours controlled rising of the reservoir. Each measurement data set was compared to the original reference data set using time-lap
Popular Abstract in Swedish I gröna växters kloroplaster finns ett s.k. sHsp-protein (small Heat shock protein) som betecknas Hsp21. Det tillhör en grupp av hjälpar-protein som kallas molekylära chaperoner. Chaperoner hjälper andra proteiner så att de inte klibbar ihop, aggregerar och blir inaktiva. Två vattenskyende ytor som sammanförs aggregerar. Genom att särskilt aggregerings-benägna (vattenskThe chloroplast-localized small heat shock protein (sHsp) Hsp21 belongs to the family of alpha-crystallin like sHsps which form large oligomeric structures and protect partly unfolded aggregation-prone proteins against aggregation. The main focus for this thesis has been on the highly conserved methionines in Hsp21. These methionine residues are situated on one side of an amphipathic alpha-helix.
In current recommendations from FAO/WHO, foods that elicit low glycaemic responses and thus have low glycaemic indices (GIs) are advocated. The rationale for this recommendation is that low-GI diets have been shown to reduce risk factors for e.g. type II diabetes and cardiovascular disease. A major problem in this context is that most important starch rich staple foods in our diet, such as potato
Popular Abstract in Swedish En populärvetenskaplig sammanfattning Det faktum att vårt minne förändra's med åldern är ett välkänt och väldokumenterat fenomen. Vilka faktorer som bidrar till denna förändring och hur de samverkar för att påverka vårt minne är däremot till stora delar forfarande ett mysterium. Minnesforskare delar vanligtvi's upp vårt minne i flera olika minnessystem. Dessa dela's upThe aim of this thesis was to examine the importance of environmental, non-cognitive, and person-based variables for memory performance in old adults. Study I was conducted in cooperation with the Gerontology Research Centre and the Department of Psychology in Lund. The investigation included 69 people with an age-range from 55-94 years and examined if certain personality factors could explain th
Popular Abstract in Swedish Ökat antal patienter som lider av kärlsjukdomar behandlas idag med interventionella metoder istället för kirurgi. Dessa metoder populärt kallade ballong sprängningar, kombineras numera oftast med inläggande av ett metallnät (stent) som hjälper till med att förstärka kärlväggen, så den inte skall falla ihop efter ballong vidgningen. Oavsett vilken metod som används, kompBackground: Restenosis is the most frequently occurring adverse event after percutaneous intravascular treatment of atherosclerotic lesions, which limits long-term patency of the intervention. Objective: The aim of the study was to evaluate if minimizing vascular injury during treatment by insertion of self-expanding stents or modifying the reparative mechanisms by local drug delivery can reduce r
In reviews regarding the management of patients with functional gastrointestinal disorders and motility disturbances within the gut nutritional aspects and dietary advice is often put forward as being of great importance. However, there are relatively few high-quality, interventional studies in the literature supporting an important role for general dietary advice to improve symptoms in these pati
High prolactin levels have been associated with increased breast cancer risk. Prolactin is essential for breast-feeding. Prolactin is lowered primarily by the first full-term pregnancy and not by subsequent pregnancies. The protection from breast cancer conferred by a long breast-feeding duration (>1 year) seems to be much greater for women with BRCA1 mutations (45%) than for women in the general
Deficiency of mannan-binding lectin (MBL) has been reported to impact susceptibility to severe nfections and atherosclerosis in systemic lupus erythematosus (SLE). In this study, MBL gene polymorphisms were analysed in 143 SLE patients and the frequency of severe infections and organ damage according to SLICC/ACR Damage Index regarding cerebrovascular accidents, angina pectoris, coronary by-pass s
It has been suggested that plasma-derived factor VIII products induce fewer inhibitors than recombinant factor VIII products. We investigated the relationship of factor VIII product type and switching between factor VIII products with the risk to develop inhibitors. This multicenter retrospective cohort study included 316 patients with severe hemophilia A born between 1990 and 2000. The outcome wa
Purpose: Several scoring systems have been developed to distinguish between benign and malignant adnexal tumors. However, few of them have been externally validated in new populations. Our aim was to compare their performance on a prospectively collected large multicenter data set. Experimental Design: In phase I of the International Ovarian Tumor Analysis multicenter study, patients with a persis
